Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay
OBJECTIVES: To evaluate the economic impact of vaccination with the pneumococcal 7-valent conjugate vaccine (PCV7) in Brazil, Chile, and Uruguay. METHODS: A decision analytic model was constructed to compare pneumococcal vaccination of children 0-5 years old with no vaccination in Brazil, Chile, and...
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Pan American Health Organization
2008
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ftdoajarticles:oai:doaj.org/article:6470844a21f4434fa434c9fb50ea73f0 2023-05-15T15:18:56+02:00 Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay Dagna O. Constenla 2008-08-01T00:00:00Z https://doaj.org/article/6470844a21f4434fa434c9fb50ea73f0 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892008000800004 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 https://doaj.org/article/6470844a21f4434fa434c9fb50ea73f0 Revista Panamericana de Salud Pública, Vol 24, Iss 2, Pp 101-112 (2008) Análisis costo-beneficio vacunación vacunas neumocócicas Brasil Chile Uruguay Cost effectiveness vaccination pneumococcal vaccines Streptococcus pneumoniae Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2008 ftdoajarticles 2022-12-31T00:41:30Z OBJECTIVES: To evaluate the economic impact of vaccination with the pneumococcal 7-valent conjugate vaccine (PCV7) in Brazil, Chile, and Uruguay. METHODS: A decision analytic model was constructed to compare pneumococcal vaccination of children 0-5 years old with no vaccination in Brazil, Chile, and Uruguay. Costs and health outcomes were analyzed from the societal perspective. Vaccine, demographic, epidemiologic, and cost data were incorporated into this economic analysis. RESULTS: At the rate of diphtheria-tetanus-pertussis (DTP) vaccine coverage and a vaccine price of US$ 53 per dose, PCV7 was projected to prevent 23 474 deaths per year in children under 5 years old in the three countries studied, thus averting 884 841 disability-adjusted life years (DALYs) yearly. To vaccinate the entire birth cohort of the three countries, total vaccine costs would be US$ 613.9 million. At US$ 53 per dose, the cost per DALY averted from a societal perspective would range from US$ 664 (Brazil) to US$ 2 019 (Chile). At a cost of US$ 10 per dose, vaccine cost is lower than the overall cost of illness averted (US$ 125 050 497 versus US$ 153 965 333), making it cost effective and cost-saving. CONCLUSIONS: The results of this study demonstrate that the incorporation of PCV7 vaccine at US$ 53 per dose confers health benefits at extra costs. It is unclear whether vaccination at the current price is affordable to these countries. OBJETIVOS: Evaluar el impacto económico de la aplicación de la vacuna antineumocócica conjugada heptavalente (PCV7) en Brasil, Chile y Uruguay. MÉTODOS: Se elaboró un modelo analítico de decisiones para comparar la vacunación antineumocócica de los niños de 0-5 años de edad con la no vacunación, en Brasil, Chile y Uruguay. Los costos y los desenlaces para la salud se analizaron desde el punto de vista de la sociedad. Al análisis económico se incorporaron los costos y los datos demográficos, epidemiológicos y de la vacuna. RESULTADOS: Con una cobertura como la de la vacuna contra la difteria, el tétanos y la ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Uruguay Daly ENVELOPE(63.761,63.761,-67.513,-67.513) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
Análisis costo-beneficio vacunación vacunas neumocócicas Brasil Chile Uruguay Cost effectiveness vaccination pneumococcal vaccines Streptococcus pneumoniae Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Análisis costo-beneficio vacunación vacunas neumocócicas Brasil Chile Uruguay Cost effectiveness vaccination pneumococcal vaccines Streptococcus pneumoniae Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Dagna O. Constenla Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay |
topic_facet |
Análisis costo-beneficio vacunación vacunas neumocócicas Brasil Chile Uruguay Cost effectiveness vaccination pneumococcal vaccines Streptococcus pneumoniae Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
OBJECTIVES: To evaluate the economic impact of vaccination with the pneumococcal 7-valent conjugate vaccine (PCV7) in Brazil, Chile, and Uruguay. METHODS: A decision analytic model was constructed to compare pneumococcal vaccination of children 0-5 years old with no vaccination in Brazil, Chile, and Uruguay. Costs and health outcomes were analyzed from the societal perspective. Vaccine, demographic, epidemiologic, and cost data were incorporated into this economic analysis. RESULTS: At the rate of diphtheria-tetanus-pertussis (DTP) vaccine coverage and a vaccine price of US$ 53 per dose, PCV7 was projected to prevent 23 474 deaths per year in children under 5 years old in the three countries studied, thus averting 884 841 disability-adjusted life years (DALYs) yearly. To vaccinate the entire birth cohort of the three countries, total vaccine costs would be US$ 613.9 million. At US$ 53 per dose, the cost per DALY averted from a societal perspective would range from US$ 664 (Brazil) to US$ 2 019 (Chile). At a cost of US$ 10 per dose, vaccine cost is lower than the overall cost of illness averted (US$ 125 050 497 versus US$ 153 965 333), making it cost effective and cost-saving. CONCLUSIONS: The results of this study demonstrate that the incorporation of PCV7 vaccine at US$ 53 per dose confers health benefits at extra costs. It is unclear whether vaccination at the current price is affordable to these countries. OBJETIVOS: Evaluar el impacto económico de la aplicación de la vacuna antineumocócica conjugada heptavalente (PCV7) en Brasil, Chile y Uruguay. MÉTODOS: Se elaboró un modelo analítico de decisiones para comparar la vacunación antineumocócica de los niños de 0-5 años de edad con la no vacunación, en Brasil, Chile y Uruguay. Los costos y los desenlaces para la salud se analizaron desde el punto de vista de la sociedad. Al análisis económico se incorporaron los costos y los datos demográficos, epidemiológicos y de la vacuna. RESULTADOS: Con una cobertura como la de la vacuna contra la difteria, el tétanos y la ... |
format |
Article in Journal/Newspaper |
author |
Dagna O. Constenla |
author_facet |
Dagna O. Constenla |
author_sort |
Dagna O. Constenla |
title |
Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay |
title_short |
Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay |
title_full |
Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay |
title_fullStr |
Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay |
title_full_unstemmed |
Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay Impacto económico de la vacuna antineumocócica conjugada en Brasil, Chile y Uruguay |
title_sort |
economic impact of pneumococcal conjugate vaccination in brazil, chile, and uruguay impacto económico de la vacuna antineumocócica conjugada en brasil, chile y uruguay |
publisher |
Pan American Health Organization |
publishDate |
2008 |
url |
https://doaj.org/article/6470844a21f4434fa434c9fb50ea73f0 |
long_lat |
ENVELOPE(63.761,63.761,-67.513,-67.513) |
geographic |
Arctic Uruguay Daly |
geographic_facet |
Arctic Uruguay Daly |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 24, Iss 2, Pp 101-112 (2008) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892008000800004 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 https://doaj.org/article/6470844a21f4434fa434c9fb50ea73f0 |
_version_ |
1766349100028002304 |