Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

• Published in: Malaria Journal
• Main Author: The WorldWide Antimalarial Resistance Network Methodology Study Group
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2019
• Subjects: Plasmodium falciparum; Treatment efficacy study; Competing risk event; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Meier
• Online Access: https://doi.org/10.1186/s12936-019-2837-4; https://doaj.org/article/642f3910338e40b0959dbe16b0a0d838

Abstract Background Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potentially preclude/pre-empt the detection of subsequent recrudescence of persistent, sub-microscopic primary infec...