Distinction of Plasmodium falciparum recrudescence and re-infection by MSP2 genotyping: A caution about unstandardized classification criteria

• Published in: Malaria Journal
• Main Authors: Thuma Philip E, Mkulama Mtawa AP, Rouse Petrica, Mharakurwa Sungano
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2008
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Lanes
• Online Access: https://doi.org/10.1186/1475-2875-7-185; https://doaj.org/article/638894a993d44696a6a4fe80a0937376

Abstract Background Plasmodium falciparum genotyping with molecular polymorphic markers is widely employed to distinguish recrudescence from re-infection in antimalarial drug efficacy monitoring programmes. However, limitations occur on agarose gel DNA measurements used to resolve the polymorphisms....