The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance
Abstract Background A clear understanding of mosquito biology is fundamental to the control efforts of mosquito-borne diseases such as malaria. Mosquito mark-release-recapture (MMRR) experiments are a popular method of measuring the survival and dispersal of disease vectors; however, examples with A...
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ftdoajarticles:oai:doaj.org/article:63225c2d7d344a87ae01a725065e34d0 2023-05-15T15:15:23+02:00 The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance Adam Saddler Katharina S. Kreppel Nakul Chitnis Thomas A. Smith Adrian Denz Jason D. Moore Mgeni M. Tambwe Sarah J. Moore 2019-12-01T00:00:00Z https://doi.org/10.1186/s12936-019-3077-3 https://doaj.org/article/63225c2d7d344a87ae01a725065e34d0 EN eng BMC https://doi.org/10.1186/s12936-019-3077-3 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-3077-3 1475-2875 https://doaj.org/article/63225c2d7d344a87ae01a725065e34d0 Malaria Journal, Vol 18, Iss 1, Pp 1-14 (2019) Mark-release-recapture Anopheles Mosquito Vector MMRR Release-recapture Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2019 ftdoajarticles https://doi.org/10.1186/s12936-019-3077-3 2022-12-31T06:14:43Z Abstract Background A clear understanding of mosquito biology is fundamental to the control efforts of mosquito-borne diseases such as malaria. Mosquito mark-release-recapture (MMRR) experiments are a popular method of measuring the survival and dispersal of disease vectors; however, examples with African malaria vectors are limited. Ethical and technical difficulties involved in carrying out MMRR studies may have held back research in this area and, therefore, a device that marks mosquitoes as they emerge from breeding sites was developed and evaluated to overcome the problems of MMRR. Methods A modified self-marking unit that marks mosquitoes with fluorescent pigment as they emerge from their breeding site was developed based on a previous design for Culex mosquitoes. The self-marking unit was first evaluated under semi-field conditions with laboratory-reared Anopheles arabiensis to determine the marking success and impact on mosquito survival. Subsequently, a field evaluation of MMRR was conducted in Yombo village, Tanzania, to examine the feasibility of the system. Results During the semi-field evaluation the self-marking units successfully marked 86% of emerging mosquitoes and there was no effect of fluorescent marker on mosquito survival. The unit successfully marked wild male and female Anopheles gambiae sensu lato (s.l.) in sufficiently large numbers to justify its use in MMRR studies. The estimated daily survival probability of An. gambiae s.l. was 0.87 (95% CI 0.69–1.10) and mean dispersal distance was 579 m (95% CI 521–636 m). Conclusions This study demonstrates the successful use of a self-marking device in an MMRR study with African malaria vectors. This method may be useful in investigating population structure and dispersal of mosquitoes for deployment and evaluation of future vector control tools, such as gene drive, and to better parameterize mathematical models. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 18 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Mark-release-recapture Anopheles Mosquito Vector MMRR Release-recapture Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Mark-release-recapture Anopheles Mosquito Vector MMRR Release-recapture Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Adam Saddler Katharina S. Kreppel Nakul Chitnis Thomas A. Smith Adrian Denz Jason D. Moore Mgeni M. Tambwe Sarah J. Moore The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
topic_facet |
Mark-release-recapture Anopheles Mosquito Vector MMRR Release-recapture Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background A clear understanding of mosquito biology is fundamental to the control efforts of mosquito-borne diseases such as malaria. Mosquito mark-release-recapture (MMRR) experiments are a popular method of measuring the survival and dispersal of disease vectors; however, examples with African malaria vectors are limited. Ethical and technical difficulties involved in carrying out MMRR studies may have held back research in this area and, therefore, a device that marks mosquitoes as they emerge from breeding sites was developed and evaluated to overcome the problems of MMRR. Methods A modified self-marking unit that marks mosquitoes with fluorescent pigment as they emerge from their breeding site was developed based on a previous design for Culex mosquitoes. The self-marking unit was first evaluated under semi-field conditions with laboratory-reared Anopheles arabiensis to determine the marking success and impact on mosquito survival. Subsequently, a field evaluation of MMRR was conducted in Yombo village, Tanzania, to examine the feasibility of the system. Results During the semi-field evaluation the self-marking units successfully marked 86% of emerging mosquitoes and there was no effect of fluorescent marker on mosquito survival. The unit successfully marked wild male and female Anopheles gambiae sensu lato (s.l.) in sufficiently large numbers to justify its use in MMRR studies. The estimated daily survival probability of An. gambiae s.l. was 0.87 (95% CI 0.69–1.10) and mean dispersal distance was 579 m (95% CI 521–636 m). Conclusions This study demonstrates the successful use of a self-marking device in an MMRR study with African malaria vectors. This method may be useful in investigating population structure and dispersal of mosquitoes for deployment and evaluation of future vector control tools, such as gene drive, and to better parameterize mathematical models. |
format |
Article in Journal/Newspaper |
author |
Adam Saddler Katharina S. Kreppel Nakul Chitnis Thomas A. Smith Adrian Denz Jason D. Moore Mgeni M. Tambwe Sarah J. Moore |
author_facet |
Adam Saddler Katharina S. Kreppel Nakul Chitnis Thomas A. Smith Adrian Denz Jason D. Moore Mgeni M. Tambwe Sarah J. Moore |
author_sort |
Adam Saddler |
title |
The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
title_short |
The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
title_full |
The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
title_fullStr |
The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
title_full_unstemmed |
The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
title_sort |
development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12936-019-3077-3 https://doaj.org/article/63225c2d7d344a87ae01a725065e34d0 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 18, Iss 1, Pp 1-14 (2019) |
op_relation |
https://doi.org/10.1186/s12936-019-3077-3 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-3077-3 1475-2875 https://doaj.org/article/63225c2d7d344a87ae01a725065e34d0 |
op_doi |
https://doi.org/10.1186/s12936-019-3077-3 |
container_title |
Malaria Journal |
container_volume |
18 |
container_issue |
1 |
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1766345745108041728 |