Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023
In December 2022 and January 2023, we isolated clade 2.3.4.4b H5N1 high-pathogenicity avian influenza (HPAI) viruses from six American crows ( Corvus brachyrhynchos ) from Prince Edward Island and a red fox ( Vulpes vulpes ) from Newfoundland, Canada. Using full-genome sequencing and phylogenetic an...
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MDPI AG
2023
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Online Access: | https://doi.org/10.3390/v15091836 https://doaj.org/article/61d3ebc9003447b2b3336500af025dbd |
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ftdoajarticles:oai:doaj.org/article:61d3ebc9003447b2b3336500af025dbd 2023-10-29T02:38:01+01:00 Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 Tamiru N. Alkie Alexander M. P. Byrne Megan E. B. Jones Benjamin C. Mollett Laura Bourque Oliver Lung Joe James Carmencita Yason Ashley C. Banyard Daniel Sullivan Anthony V. Signore Andrew S. Lang Meghan Baker Beverly Dawe Ian H. Brown Yohannes Berhane 2023-08-01T00:00:00Z https://doi.org/10.3390/v15091836 https://doaj.org/article/61d3ebc9003447b2b3336500af025dbd EN eng MDPI AG https://www.mdpi.com/1999-4915/15/9/1836 https://doaj.org/toc/1999-4915 doi:10.3390/v15091836 1999-4915 https://doaj.org/article/61d3ebc9003447b2b3336500af025dbd Viruses, Vol 15, Iss 1836, p 1836 (2023) H5N1 clade 2.3.4.4b American crow red fox Canada re-introduction Microbiology QR1-502 article 2023 ftdoajarticles https://doi.org/10.3390/v15091836 2023-10-01T00:36:39Z In December 2022 and January 2023, we isolated clade 2.3.4.4b H5N1 high-pathogenicity avian influenza (HPAI) viruses from six American crows ( Corvus brachyrhynchos ) from Prince Edward Island and a red fox ( Vulpes vulpes ) from Newfoundland, Canada. Using full-genome sequencing and phylogenetic analysis, these viruses were found to fall into two distinct phylogenetic clusters: one group containing H5N1 viruses that had been circulating in North and South America since late 2021, and the other one containing European H5N1 viruses reported in late 2022. The transatlantic re-introduction for the second time by pelagic/Icelandic bird migration via the same route used during the 2021 incursion of Eurasian origin H5N1 viruses into North America demonstrates that migratory birds continue to be the driving force for transcontinental dissemination of the virus. This new detection further demonstrates the continual long-term threat of H5N1 viruses for poultry and mammals and the subsequent impact on various wild bird populations wherever these viruses emerge. The continual emergence of clade 2.3.4.4b H5Nx viruses requires vigilant surveillance in wild birds, particularly in areas of the Americas, which lie within the migratory corridors for long-distance migratory birds originating from Europe and Asia. Although H5Nx viruses have been detected at higher rates in North America since 2021, a bidirectional flow of H5Nx genes of American origin viruses to Europe has never been reported. In the future, coordinated and systematic surveillance programs for HPAI viruses need to be launched between European and North American agencies. Article in Journal/Newspaper Newfoundland Prince Edward Island Directory of Open Access Journals: DOAJ Articles Viruses 15 9 1836 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
H5N1 clade 2.3.4.4b American crow red fox Canada re-introduction Microbiology QR1-502 |
spellingShingle |
H5N1 clade 2.3.4.4b American crow red fox Canada re-introduction Microbiology QR1-502 Tamiru N. Alkie Alexander M. P. Byrne Megan E. B. Jones Benjamin C. Mollett Laura Bourque Oliver Lung Joe James Carmencita Yason Ashley C. Banyard Daniel Sullivan Anthony V. Signore Andrew S. Lang Meghan Baker Beverly Dawe Ian H. Brown Yohannes Berhane Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 |
topic_facet |
H5N1 clade 2.3.4.4b American crow red fox Canada re-introduction Microbiology QR1-502 |
description |
In December 2022 and January 2023, we isolated clade 2.3.4.4b H5N1 high-pathogenicity avian influenza (HPAI) viruses from six American crows ( Corvus brachyrhynchos ) from Prince Edward Island and a red fox ( Vulpes vulpes ) from Newfoundland, Canada. Using full-genome sequencing and phylogenetic analysis, these viruses were found to fall into two distinct phylogenetic clusters: one group containing H5N1 viruses that had been circulating in North and South America since late 2021, and the other one containing European H5N1 viruses reported in late 2022. The transatlantic re-introduction for the second time by pelagic/Icelandic bird migration via the same route used during the 2021 incursion of Eurasian origin H5N1 viruses into North America demonstrates that migratory birds continue to be the driving force for transcontinental dissemination of the virus. This new detection further demonstrates the continual long-term threat of H5N1 viruses for poultry and mammals and the subsequent impact on various wild bird populations wherever these viruses emerge. The continual emergence of clade 2.3.4.4b H5Nx viruses requires vigilant surveillance in wild birds, particularly in areas of the Americas, which lie within the migratory corridors for long-distance migratory birds originating from Europe and Asia. Although H5Nx viruses have been detected at higher rates in North America since 2021, a bidirectional flow of H5Nx genes of American origin viruses to Europe has never been reported. In the future, coordinated and systematic surveillance programs for HPAI viruses need to be launched between European and North American agencies. |
format |
Article in Journal/Newspaper |
author |
Tamiru N. Alkie Alexander M. P. Byrne Megan E. B. Jones Benjamin C. Mollett Laura Bourque Oliver Lung Joe James Carmencita Yason Ashley C. Banyard Daniel Sullivan Anthony V. Signore Andrew S. Lang Meghan Baker Beverly Dawe Ian H. Brown Yohannes Berhane |
author_facet |
Tamiru N. Alkie Alexander M. P. Byrne Megan E. B. Jones Benjamin C. Mollett Laura Bourque Oliver Lung Joe James Carmencita Yason Ashley C. Banyard Daniel Sullivan Anthony V. Signore Andrew S. Lang Meghan Baker Beverly Dawe Ian H. Brown Yohannes Berhane |
author_sort |
Tamiru N. Alkie |
title |
Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 |
title_short |
Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 |
title_full |
Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 |
title_fullStr |
Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 |
title_full_unstemmed |
Recurring Trans-Atlantic Incursion of Clade 2.3.4.4b H5N1 Viruses by Long Distance Migratory Birds from Northern Europe to Canada in 2022/2023 |
title_sort |
recurring trans-atlantic incursion of clade 2.3.4.4b h5n1 viruses by long distance migratory birds from northern europe to canada in 2022/2023 |
publisher |
MDPI AG |
publishDate |
2023 |
url |
https://doi.org/10.3390/v15091836 https://doaj.org/article/61d3ebc9003447b2b3336500af025dbd |
genre |
Newfoundland Prince Edward Island |
genre_facet |
Newfoundland Prince Edward Island |
op_source |
Viruses, Vol 15, Iss 1836, p 1836 (2023) |
op_relation |
https://www.mdpi.com/1999-4915/15/9/1836 https://doaj.org/toc/1999-4915 doi:10.3390/v15091836 1999-4915 https://doaj.org/article/61d3ebc9003447b2b3336500af025dbd |
op_doi |
https://doi.org/10.3390/v15091836 |
container_title |
Viruses |
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15 |
container_issue |
9 |
container_start_page |
1836 |
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1781063639836393472 |