Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014
Introduction: The Colombian National Antimicrobial Resistance Monitoring System for the surveillance of healthcare-associated infections was set up to meet this problem in the third quarter of 2012. Objective: To describe resistance profiles and laboratory-based surveillance based on the information...
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ftdoajarticles:oai:doaj.org/article:61850d3f1e214cfe9f44c46c929a16bf 2023-05-15T15:12:15+02:00 Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 María Victoria Ovalle Sandra Yamile Saavedra María Nilse González Andrea Melissa Hidalgo Carolina Duarte Mauricio Beltrán 2017-12-01T00:00:00Z https://doi.org/10.7705/biomedica.v37i4.3432 https://doaj.org/article/61850d3f1e214cfe9f44c46c929a16bf EN ES eng spa Instituto Nacional de Salud https://www.revistabiomedica.org/index.php/biomedica/article/view/3432 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v37i4.3432 https://doaj.org/article/61850d3f1e214cfe9f44c46c929a16bf Biomédica: revista del Instituto Nacional de Salud, Vol 37, Iss 4, Pp 473-485 (2017) Drug resistance microbial bacterial infections surveillance carbapenems Enterobacteriaceae Acinetobacter Pseudomonas Medicine R Arctic medicine. Tropical medicine RC955-962 article 2017 ftdoajarticles https://doi.org/10.7705/biomedica.v37i4.3432 2022-12-30T23:59:13Z Introduction: The Colombian National Antimicrobial Resistance Monitoring System for the surveillance of healthcare-associated infections was set up to meet this problem in the third quarter of 2012. Objective: To describe resistance profiles and laboratory-based surveillance based on the information collected by the System. Materials and methods: We conducted a retrospective and descriptive study of the information notified to the Colombian Public Health Surveillance System (Sivigila), and in the Whonet databases covering the period from July 2012 to December 2014 provided by the primary data-generating units in the country, as well as laboratory surveillance results from 1,642 phenotypic and genotypic tests on carbapenemase isolates (927 from Enterobacteriaceae, 614 from Pseudomonas spp. and 101 from Acinetobacter spp.). Results: There was a significant increase in Escherichia coli resistance to third-generation cephalosporins (reaching 26.3% in ICUs and 22.5% in other hospital wards), and Klebsiella pneumoniae resistance to ertapenem also increased (reaching 14.6% in ICUs). Acinetobacter baumannii carbapenem resistance exceeded 50% in ICUs whereas Pseudomonas aeruginosa had lower carbapenem resistance (38.8%). KPC (n = 574) and NDM (n=57) were the most frequently occurring carbapenemases in Enterobacteriaceae, VIM (n=229) and KPC (n=114) in P. aeruginosa, and OXA-23 in A. baumannii (n=87); several carbapenemase combinations were identified, KPC + VIM being the most common in Pseudomonas spp. and Enterobacteriaceae. Conclusion: The data from the surveillance of healthcare-associated infections revealed significant carbapenem resistance profiles and antimicrobial resistance mechanisms circulating in Colombian healthcare institutions. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Biomédica 37 4 473 |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English Spanish |
topic |
Drug resistance microbial bacterial infections surveillance carbapenems Enterobacteriaceae Acinetobacter Pseudomonas Medicine R Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Drug resistance microbial bacterial infections surveillance carbapenems Enterobacteriaceae Acinetobacter Pseudomonas Medicine R Arctic medicine. Tropical medicine RC955-962 María Victoria Ovalle Sandra Yamile Saavedra María Nilse González Andrea Melissa Hidalgo Carolina Duarte Mauricio Beltrán Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 |
topic_facet |
Drug resistance microbial bacterial infections surveillance carbapenems Enterobacteriaceae Acinetobacter Pseudomonas Medicine R Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction: The Colombian National Antimicrobial Resistance Monitoring System for the surveillance of healthcare-associated infections was set up to meet this problem in the third quarter of 2012. Objective: To describe resistance profiles and laboratory-based surveillance based on the information collected by the System. Materials and methods: We conducted a retrospective and descriptive study of the information notified to the Colombian Public Health Surveillance System (Sivigila), and in the Whonet databases covering the period from July 2012 to December 2014 provided by the primary data-generating units in the country, as well as laboratory surveillance results from 1,642 phenotypic and genotypic tests on carbapenemase isolates (927 from Enterobacteriaceae, 614 from Pseudomonas spp. and 101 from Acinetobacter spp.). Results: There was a significant increase in Escherichia coli resistance to third-generation cephalosporins (reaching 26.3% in ICUs and 22.5% in other hospital wards), and Klebsiella pneumoniae resistance to ertapenem also increased (reaching 14.6% in ICUs). Acinetobacter baumannii carbapenem resistance exceeded 50% in ICUs whereas Pseudomonas aeruginosa had lower carbapenem resistance (38.8%). KPC (n = 574) and NDM (n=57) were the most frequently occurring carbapenemases in Enterobacteriaceae, VIM (n=229) and KPC (n=114) in P. aeruginosa, and OXA-23 in A. baumannii (n=87); several carbapenemase combinations were identified, KPC + VIM being the most common in Pseudomonas spp. and Enterobacteriaceae. Conclusion: The data from the surveillance of healthcare-associated infections revealed significant carbapenem resistance profiles and antimicrobial resistance mechanisms circulating in Colombian healthcare institutions. |
format |
Article in Journal/Newspaper |
author |
María Victoria Ovalle Sandra Yamile Saavedra María Nilse González Andrea Melissa Hidalgo Carolina Duarte Mauricio Beltrán |
author_facet |
María Victoria Ovalle Sandra Yamile Saavedra María Nilse González Andrea Melissa Hidalgo Carolina Duarte Mauricio Beltrán |
author_sort |
María Victoria Ovalle |
title |
Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 |
title_short |
Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 |
title_full |
Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 |
title_fullStr |
Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 |
title_full_unstemmed |
Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014 |
title_sort |
results of the national surveillance of antimicrobial resistance of enterobacteriaceae and gram negative bacilli in health care-associated infections in colombia, 2012-2014 |
publisher |
Instituto Nacional de Salud |
publishDate |
2017 |
url |
https://doi.org/10.7705/biomedica.v37i4.3432 https://doaj.org/article/61850d3f1e214cfe9f44c46c929a16bf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Biomédica: revista del Instituto Nacional de Salud, Vol 37, Iss 4, Pp 473-485 (2017) |
op_relation |
https://www.revistabiomedica.org/index.php/biomedica/article/view/3432 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v37i4.3432 https://doaj.org/article/61850d3f1e214cfe9f44c46c929a16bf |
op_doi |
https://doi.org/10.7705/biomedica.v37i4.3432 |
container_title |
Biomédica |
container_volume |
37 |
container_issue |
4 |
container_start_page |
473 |
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1766342962908758016 |