IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase
Abstract INTRODUCTION: High percentages of structural identity and cross-immunoreactivity have been reported between potato apyrase and Schistosoma mansoni ATP diphosphohydrolase (SmATPDases) isoforms, showing the existence of particular epitopes shared between these proteins. METHODS: Potato apyras...
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Online Access: | https://doi.org/10.1590/0037-8682-0139-2018 https://doaj.org/article/6126f72de2a4441a978886b656437e6d |
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ftdoajarticles:oai:doaj.org/article:6126f72de2a4441a978886b656437e6d 2023-05-15T15:00:12+02:00 IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase Michélia Antônia do Nascimento Gusmão Nayara Braga Emídio Danielle Gomes Marconato Priscila Silva Grijó Farani Luiz Felipe Maniezzi Paulo Marcos Zech Coelho Rodrigo Correa Oliveira Eveline Gomes Vasconcelos Priscila de Faria-Pinto 2019-03-01T00:00:00Z https://doi.org/10.1590/0037-8682-0139-2018 https://doaj.org/article/6126f72de2a4441a978886b656437e6d EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100625&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0139-2018 https://doaj.org/article/6126f72de2a4441a978886b656437e6d Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss 0 (2019) ATP diphosphohydrolase IgE Potato apyrase Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1590/0037-8682-0139-2018 2022-12-31T02:58:05Z Abstract INTRODUCTION: High percentages of structural identity and cross-immunoreactivity have been reported between potato apyrase and Schistosoma mansoni ATP diphosphohydrolase (SmATPDases) isoforms, showing the existence of particular epitopes shared between these proteins. METHODS: Potato apyrase was employed using ELISA, western blot, and mouse immunization methods to verify IgE reactivity. RESULTS: Most of the schistosomiasis patient’s (75%) serum was seropositive for potato apyrase and this protein was recognized using western blotting, suggesting that parasite and plant proteins share IgE-binding epitopes. C57BL/6 mice immunized with potato apyrase showed increased IgE antibody production. CONCLUSIONS: Potato apyrase and SmATPDases have IgE-binding epitopes. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 52 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
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ATP diphosphohydrolase IgE Potato apyrase Arctic medicine. Tropical medicine RC955-962 |
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ATP diphosphohydrolase IgE Potato apyrase Arctic medicine. Tropical medicine RC955-962 Michélia Antônia do Nascimento Gusmão Nayara Braga Emídio Danielle Gomes Marconato Priscila Silva Grijó Farani Luiz Felipe Maniezzi Paulo Marcos Zech Coelho Rodrigo Correa Oliveira Eveline Gomes Vasconcelos Priscila de Faria-Pinto IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
topic_facet |
ATP diphosphohydrolase IgE Potato apyrase Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: High percentages of structural identity and cross-immunoreactivity have been reported between potato apyrase and Schistosoma mansoni ATP diphosphohydrolase (SmATPDases) isoforms, showing the existence of particular epitopes shared between these proteins. METHODS: Potato apyrase was employed using ELISA, western blot, and mouse immunization methods to verify IgE reactivity. RESULTS: Most of the schistosomiasis patient’s (75%) serum was seropositive for potato apyrase and this protein was recognized using western blotting, suggesting that parasite and plant proteins share IgE-binding epitopes. C57BL/6 mice immunized with potato apyrase showed increased IgE antibody production. CONCLUSIONS: Potato apyrase and SmATPDases have IgE-binding epitopes. |
format |
Article in Journal/Newspaper |
author |
Michélia Antônia do Nascimento Gusmão Nayara Braga Emídio Danielle Gomes Marconato Priscila Silva Grijó Farani Luiz Felipe Maniezzi Paulo Marcos Zech Coelho Rodrigo Correa Oliveira Eveline Gomes Vasconcelos Priscila de Faria-Pinto |
author_facet |
Michélia Antônia do Nascimento Gusmão Nayara Braga Emídio Danielle Gomes Marconato Priscila Silva Grijó Farani Luiz Felipe Maniezzi Paulo Marcos Zech Coelho Rodrigo Correa Oliveira Eveline Gomes Vasconcelos Priscila de Faria-Pinto |
author_sort |
Michélia Antônia do Nascimento Gusmão |
title |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_short |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_full |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_fullStr |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_full_unstemmed |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_sort |
ige antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2019 |
url |
https://doi.org/10.1590/0037-8682-0139-2018 https://doaj.org/article/6126f72de2a4441a978886b656437e6d |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss 0 (2019) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100625&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0139-2018 https://doaj.org/article/6126f72de2a4441a978886b656437e6d |
op_doi |
https://doi.org/10.1590/0037-8682-0139-2018 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
52 |
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