Co-infection and risk factors of tuberculosis in a Mexican HIV+ population Coinfecção e fatores de risco de tuberculose em uma população Mexicana com HIV+

• Main Authors: Roberto Zenteno-Cuevas, Evangelina Montes-Villaseñor, Jaime Morales-Romero, Gastón Coronel-Martín del Campo, Betzaida Cuevas
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2011
• Subjects: Tuberculose; HIV; Fatores de risco; Coinfecção; Tuberculosis; Risk factors; Co-infection; Arctic medicine. Tropical medicine; RC955-962; Arctic; Droga
• Online Access: https://doaj.org/article/60e5a1b6b9fa410c8aa7dea5bcef0845

INTRODUCTION: The situation of tuberculosis (TB) is being modified by the human immunodeficiency virus (HIV), which is increasing the occurrence of new cases and the generation of drug resistant strains, affecting not only the people infected with HIV, but also their close contacts and the general population, conforming a serious public health concern. However, the magnitudes of the factors associated to this co-infection differ considerably in relation to the population groups and geographical areas. METHODS: In order to evaluate the prevalence and risk factors for the co-infection of tuberculosis (TB) in a population with human immunodeficiency virus (HIV+) in the Southeast of Mexico, we made the analysis of clinical and epidemiological variables and the diagnosis of tuberculosis by isolation of mycobacteria from respiratory samples. RESULTS: From the 147 HIV+ individuals analyzed, 12 were culture positive; this shows a prevalence of 8% for the co-infection. The only variable found with statistical significance for the co-infection was the number of CD4-T < 200 cells/mm³, OR 13 (95%, CI 2-106 vs 12-109). CONCLUSIONS: To our knowledge this is the first report describing the factors associated with tuberculosis co -infection with HIV in a population from Southern Mexico. The low number of CD4 T-cells was the only variable associated with the TB co-infection and the rest of the variables provide scenarios that require specific and particular interventions for this population group. INTRODUÇÃO: A situação da tuberculose (TB) foi modificada pelo vírus da imunodeficiência humana (HIV). Com isso, aumentou-se a ocorrência de novos casos de TB e a geração de cepas resistentes à droga, afetando não só as pessoas infectadas com HIV, mas também seus contatos próximos e da população em geral, gerando um sério problema de saúde pública. No entanto, a magnitude dos fatores associados à esta coinfecção diferem consideravelmente em relação aos grupos populacionais e áreas geográficas. MÉTODOS: Para avaliar a prevalência da ...