Leishmania donovani infection enhances lateral mobility of macrophage membrane protein which is reversed by liposomal cholesterol.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Moumita Ghosh, Koushik Roy, Dipanwita Das Mukherjee, Gopal Chakrabarti, Kingshuk Roy Choudhury, Syamal Roy
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2014
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Lent
• Online Access: https://doi.org/10.1371/journal.pntd.0003367; https://doaj.org/article/60d2544b1ca94fd6ad38fb778d8bb8e0

The protozoan parasite Leishmania donovani (LD) reduces cellular cholesterol of the host possibly for its own benefit. Cholesterol is mostly present in the specialized compartment of the plasma membrane. The relation between mobility of membrane proteins and cholesterol depletion from membrane conti...