Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm
Program Coordinating Committee and OEPA staffOnchocerciasis Elimination Program for the Americas, Guatemala City, GuatemalaAbstract: Control and elimination of human onchocerciasis using mass drug administration of ivermectin (Mectizan®) has proceeded with marked gains over the past 10 years, more s...
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ftdoajarticles:oai:doaj.org/article:604084d6c4614f30a33ae04ab942ddb5 2023-05-15T15:06:25+02:00 Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm Program Coordinating Committee OEPA staff 2012-05-01T00:00:00Z https://doaj.org/article/604084d6c4614f30a33ae04ab942ddb5 EN eng Dove Medical Press http://www.dovepress.com/guide-to-detecting-a-potential-recrudescence-of-onchocerciasis-during--a9929 https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/604084d6c4614f30a33ae04ab942ddb5 Research and Reports in Tropical Medicine, Vol 2012, Iss default, Pp 21-33 (2012) Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles 2022-12-31T09:18:25Z Program Coordinating Committee and OEPA staffOnchocerciasis Elimination Program for the Americas, Guatemala City, GuatemalaAbstract: Control and elimination of human onchocerciasis using mass drug administration of ivermectin (Mectizan®) has proceeded with marked gains over the past 10 years, more so in the Americas than in Africa. In the Americas, the initial focus on elimination of ocular morbidity has shifted to interruption of transmission, and the program has refined both the process leading up to interruption of transmission as well as the critical period following cessation of mass drug administration to document that there is no recrudescence of transmission. This is called the posttreatment surveillance (PTS) period. This report describes the aims, phases, and methodology of PTS as operationalized by the endemic countries and the Onchocerciasis Elimination Program for the Americas. Successful completion of the PTS period without signs of recrudescence leads to a country request for certification of elimination by the World Health Organization. As elimination of onchocerciasis in the Americas proceeds and emphasis in Africa switches from control to elimination, the PTS guide should prove invaluable to those programs going forward.Keywords: Onchocerca volvulus, onchocerciasis, ivermectin, Mectizan®, recrudescence, surveillance Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 Program Coordinating Committee OEPA staff Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Program Coordinating Committee and OEPA staffOnchocerciasis Elimination Program for the Americas, Guatemala City, GuatemalaAbstract: Control and elimination of human onchocerciasis using mass drug administration of ivermectin (Mectizan®) has proceeded with marked gains over the past 10 years, more so in the Americas than in Africa. In the Americas, the initial focus on elimination of ocular morbidity has shifted to interruption of transmission, and the program has refined both the process leading up to interruption of transmission as well as the critical period following cessation of mass drug administration to document that there is no recrudescence of transmission. This is called the posttreatment surveillance (PTS) period. This report describes the aims, phases, and methodology of PTS as operationalized by the endemic countries and the Onchocerciasis Elimination Program for the Americas. Successful completion of the PTS period without signs of recrudescence leads to a country request for certification of elimination by the World Health Organization. As elimination of onchocerciasis in the Americas proceeds and emphasis in Africa switches from control to elimination, the PTS guide should prove invaluable to those programs going forward.Keywords: Onchocerca volvulus, onchocerciasis, ivermectin, Mectizan®, recrudescence, surveillance |
format |
Article in Journal/Newspaper |
author |
Program Coordinating Committee OEPA staff |
author_facet |
Program Coordinating Committee OEPA staff |
author_sort |
Program Coordinating Committee |
title |
Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm |
title_short |
Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm |
title_full |
Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm |
title_fullStr |
Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm |
title_full_unstemmed |
Guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the American paradigm |
title_sort |
guide to detecting a potential recrudescence of onchocerciasis during the posttreatment surveillance period: the american paradigm |
publisher |
Dove Medical Press |
publishDate |
2012 |
url |
https://doaj.org/article/604084d6c4614f30a33ae04ab942ddb5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Research and Reports in Tropical Medicine, Vol 2012, Iss default, Pp 21-33 (2012) |
op_relation |
http://www.dovepress.com/guide-to-detecting-a-potential-recrudescence-of-onchocerciasis-during--a9929 https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/604084d6c4614f30a33ae04ab942ddb5 |
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1766338024191295488 |