Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis
Abstract INTRODUCTION In patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) gait disturbance is a predominant feature that leads to falls and fractures, which can further aggravate disability. We sought to evaluate the impact of fractures and orthopedic surgeries in pa...
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ftdoajarticles:oai:doaj.org/article:5fe7fe8534314e70b5248ab88e2fb828 2023-05-15T15:08:44+02:00 Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis Pablo Julca-Copello Alvaro Schwalb Rodrigo Cachay Martín Tipismana Carolina Alvarez Fernando Mejía Elsa González-Lagos Eduardo Gotuzzo 2020-09-01T00:00:00Z https://doi.org/10.1590/0037-8682-0101-2020 https://doaj.org/article/5fe7fe8534314e70b5248ab88e2fb828 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100342&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0101-2020 https://doaj.org/article/5fe7fe8534314e70b5248ab88e2fb828 Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2020) HTLV-1 HAM/TSP Fractures Arctic medicine. Tropical medicine RC955-962 article 2020 ftdoajarticles https://doi.org/10.1590/0037-8682-0101-2020 2022-12-30T21:38:58Z Abstract INTRODUCTION In patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) gait disturbance is a predominant feature that leads to falls and fractures, which can further aggravate disability. We sought to evaluate the impact of fractures and orthopedic surgeries in patients with HAM/TSP. METHODS: We retrieved the medical records of HAM/TSP patients enrolled in our study center’s HTLV-1 clinical cohort between 1989-2018. The selection criteria included: (1) diagnosis of HTLV-1 infection using two enzyme-linked immunosorbent assays and/or a confirmatory test, (2) clinical diagnosis of HAM/TSP by neurological assessment, and (3) fractures associated with HAM/TSP. RESULTS: We identified 24 cases of fractures, 70% of which were females. The median age at the time of fracture was 60 years (IQR=24). Six cases reported fractures in patients under 45 years old. Ten patients (42%) had hip/coccyx fractures, seven (29%) were in the lower extremities, and four (17%) in the upper extremities. Half of these patients reported the use of wheelchairs. Five patients who had previously used canes required the use of wheelchairs after the reported fracture. Eight patients underwent corrective orthopedic surgery as a result of the fracture. CONCLUSIONS: For HAM/TSP patients, fractures are a complication that can exacerbate their severe impairment. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 53 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
HTLV-1 HAM/TSP Fractures Arctic medicine. Tropical medicine RC955-962 |
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HTLV-1 HAM/TSP Fractures Arctic medicine. Tropical medicine RC955-962 Pablo Julca-Copello Alvaro Schwalb Rodrigo Cachay Martín Tipismana Carolina Alvarez Fernando Mejía Elsa González-Lagos Eduardo Gotuzzo Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis |
topic_facet |
HTLV-1 HAM/TSP Fractures Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION In patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) gait disturbance is a predominant feature that leads to falls and fractures, which can further aggravate disability. We sought to evaluate the impact of fractures and orthopedic surgeries in patients with HAM/TSP. METHODS: We retrieved the medical records of HAM/TSP patients enrolled in our study center’s HTLV-1 clinical cohort between 1989-2018. The selection criteria included: (1) diagnosis of HTLV-1 infection using two enzyme-linked immunosorbent assays and/or a confirmatory test, (2) clinical diagnosis of HAM/TSP by neurological assessment, and (3) fractures associated with HAM/TSP. RESULTS: We identified 24 cases of fractures, 70% of which were females. The median age at the time of fracture was 60 years (IQR=24). Six cases reported fractures in patients under 45 years old. Ten patients (42%) had hip/coccyx fractures, seven (29%) were in the lower extremities, and four (17%) in the upper extremities. Half of these patients reported the use of wheelchairs. Five patients who had previously used canes required the use of wheelchairs after the reported fracture. Eight patients underwent corrective orthopedic surgery as a result of the fracture. CONCLUSIONS: For HAM/TSP patients, fractures are a complication that can exacerbate their severe impairment. |
format |
Article in Journal/Newspaper |
author |
Pablo Julca-Copello Alvaro Schwalb Rodrigo Cachay Martín Tipismana Carolina Alvarez Fernando Mejía Elsa González-Lagos Eduardo Gotuzzo |
author_facet |
Pablo Julca-Copello Alvaro Schwalb Rodrigo Cachay Martín Tipismana Carolina Alvarez Fernando Mejía Elsa González-Lagos Eduardo Gotuzzo |
author_sort |
Pablo Julca-Copello |
title |
Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis |
title_short |
Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis |
title_full |
Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis |
title_fullStr |
Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis |
title_full_unstemmed |
Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis |
title_sort |
impact of fractures and orthopedic surgeries in patients with htlv-1 associated myelopathy/tropical spastic paraparesis |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2020 |
url |
https://doi.org/10.1590/0037-8682-0101-2020 https://doaj.org/article/5fe7fe8534314e70b5248ab88e2fb828 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2020) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100342&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0101-2020 https://doaj.org/article/5fe7fe8534314e70b5248ab88e2fb828 |
op_doi |
https://doi.org/10.1590/0037-8682-0101-2020 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
53 |
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