Missed, Not Missing: Phylogenomic Evidence for the Existence of Avian FoxP3.

• Published in: PLOS ONE
• Main Authors: Michael P Denyer, Dammy Y Pinheiro, Oliver A Garden, Adrian J Shepherd
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2016
• Subjects: Medicine; R; Science; Q; Parus; Falco peregrinus; peregrine falcon
• Online Access: https://doi.org/10.1371/journal.pone.0150988; https://doaj.org/article/5fcc784223b44c9ba30b386e0b0cc806

The Forkhead box transcription factor FoxP3 is pivotal to the development and function of regulatory T cells (Tregs), which make a major contribution to peripheral tolerance. FoxP3 is believed to perform a regulatory role in all the vertebrate species in which it has been detected. The prevailing vi...