Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism
Scorpions are venomous arthropods of the Arachnida class and are considered relatives of spiders, ticks and mites. There is not any study about the biochemical effects of Androctonus crassicauda (Olivier, 1807) venom. Therefore, in the present study, we aimed at evaluating the toxicity of the venom...
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ftdoajarticles:oai:doaj.org/article:5f867ecbd42a4a0ba4ac20c356a3d913 2023-05-15T15:06:19+02:00 Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism O. Ozkan F. Bakir S. Adiguzel 2008-01-01T00:00:00Z https://doi.org/10.1590/S1678-91992008000100004 https://doaj.org/article/5f867ecbd42a4a0ba4ac20c356a3d913 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000100004 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992008000100004 1678-9199 https://doaj.org/article/5f867ecbd42a4a0ba4ac20c356a3d913 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 1, Pp 45-57 (2008) scorpions Androctonus crassicauda venom rats biochemical parameters Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2008 ftdoajarticles https://doi.org/10.1590/S1678-91992008000100004 2022-12-31T11:13:05Z Scorpions are venomous arthropods of the Arachnida class and are considered relatives of spiders, ticks and mites. There is not any study about the biochemical effects of Androctonus crassicauda (Olivier, 1807) venom. Therefore, in the present study, we aimed at evaluating the toxicity of the venom from A. crassicauda, which is responsible for a number of deaths of infants, children and adults in tropical and subtropical countries. For this purpose, rats (n=35) were divided into seven groups of five animals each; venom solutions (250µg/kg) were subcutaneously injected into rats; blood samples were taken from each animal at various times; and serum biochemical parameters were measured (levels of total proteins, total bilirubin, albumin, globulin, urea, creatinine, uric acid, glucose, cholesterol, triglycerides, sodium, chlorine, potassium and calcium, and the activity of the enzymes alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase). Serum levels of glucose, cholesterol, aspartate aminotransferase, alanine aminotransferase and uric acid increased in envenomed animals, compared to controls. There was a statistically positive correlation between Na+ and Cl- ions. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 14 1 |
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op_collection_id |
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language |
English |
topic |
scorpions Androctonus crassicauda venom rats biochemical parameters Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
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scorpions Androctonus crassicauda venom rats biochemical parameters Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 O. Ozkan F. Bakir S. Adiguzel Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
topic_facet |
scorpions Androctonus crassicauda venom rats biochemical parameters Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Scorpions are venomous arthropods of the Arachnida class and are considered relatives of spiders, ticks and mites. There is not any study about the biochemical effects of Androctonus crassicauda (Olivier, 1807) venom. Therefore, in the present study, we aimed at evaluating the toxicity of the venom from A. crassicauda, which is responsible for a number of deaths of infants, children and adults in tropical and subtropical countries. For this purpose, rats (n=35) were divided into seven groups of five animals each; venom solutions (250µg/kg) were subcutaneously injected into rats; blood samples were taken from each animal at various times; and serum biochemical parameters were measured (levels of total proteins, total bilirubin, albumin, globulin, urea, creatinine, uric acid, glucose, cholesterol, triglycerides, sodium, chlorine, potassium and calcium, and the activity of the enzymes alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase). Serum levels of glucose, cholesterol, aspartate aminotransferase, alanine aminotransferase and uric acid increased in envenomed animals, compared to controls. There was a statistically positive correlation between Na+ and Cl- ions. |
format |
Article in Journal/Newspaper |
author |
O. Ozkan F. Bakir S. Adiguzel |
author_facet |
O. Ozkan F. Bakir S. Adiguzel |
author_sort |
O. Ozkan |
title |
Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
title_short |
Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
title_full |
Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
title_fullStr |
Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
title_full_unstemmed |
Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism |
title_sort |
effects of androctonus crassicauda (olivier, 1807) (scorpiones: buthidae) venom on rat metabolism |
publisher |
SciELO |
publishDate |
2008 |
url |
https://doi.org/10.1590/S1678-91992008000100004 https://doaj.org/article/5f867ecbd42a4a0ba4ac20c356a3d913 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 1, Pp 45-57 (2008) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000100004 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992008000100004 1678-9199 https://doaj.org/article/5f867ecbd42a4a0ba4ac20c356a3d913 |
op_doi |
https://doi.org/10.1590/S1678-91992008000100004 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
14 |
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1 |
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1766337953136640000 |