Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens
Salmon rickettsial septicaemia (SRS) is the infectious disease that produces the highest losses in the Chilean salmon industry. As a new strategy for the control of SRS outbreaks, in this study we evaluated the effect of alginate-encapsulated Piscirickettsia salmonis antigens (AEPSA) incorporated in...
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ftdoajarticles:oai:doaj.org/article:5f801d28f67c42daa57ef308d3e14178 2023-05-15T15:30:47+02:00 Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens Daniela Sotomayor-Gerding José Miguel Troncoso Alejandro Pino Felipe Almendras Mónica Rubilar Diaz 2020-08-01T00:00:00Z https://doi.org/10.3390/vaccines8030450 https://doaj.org/article/5f801d28f67c42daa57ef308d3e14178 EN eng MDPI AG https://www.mdpi.com/2076-393X/8/3/450 https://doaj.org/toc/2076-393X doi:10.3390/vaccines8030450 2076-393X https://doaj.org/article/5f801d28f67c42daa57ef308d3e14178 Vaccines, Vol 8, Iss 450, p 450 (2020) microencapsulation alginate aerodynamically assisted jetting system Piscirickettsia salmonis antigen oral vaccine Medicine R article 2020 ftdoajarticles https://doi.org/10.3390/vaccines8030450 2023-01-08T01:29:22Z Salmon rickettsial septicaemia (SRS) is the infectious disease that produces the highest losses in the Chilean salmon industry. As a new strategy for the control of SRS outbreaks, in this study we evaluated the effect of alginate-encapsulated Piscirickettsia salmonis antigens (AEPSA) incorporated in the feed as an oral vaccine to induce the immune response in Atlantic salmon ( Salmo salar ). Fish were distributed into three vaccination groups (injectable, oral high dose, oral low dose). Feed intake and fish growth were recorded during the trial. The P. salmonis -specific IgM levels in blood plasma were measured by ELISA. Alginate microparticles containing the antigen were effectively incorporated in fish feed to produce the oral vaccine. Incorporation of AEPSA did not affect the palatability of the feed or the fish appetite. Furthermore, the oral vaccine did not have a negative effect on fish growth. Finally, the oral vaccine (high and low dose) produced an acquired immune response (IgM) similar to the injectable vaccine, generating a statistically significant increase in the IgM levels at 840-degree days for both experimental groups. These findings suggest that AEPSA incorporated in the feed can be an effective alternative to boost the immune response in Atlantic salmon ( S. salar ). Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles Vaccines 8 3 450 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
microencapsulation alginate aerodynamically assisted jetting system Piscirickettsia salmonis antigen oral vaccine Medicine R |
spellingShingle |
microencapsulation alginate aerodynamically assisted jetting system Piscirickettsia salmonis antigen oral vaccine Medicine R Daniela Sotomayor-Gerding José Miguel Troncoso Alejandro Pino Felipe Almendras Mónica Rubilar Diaz Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens |
topic_facet |
microencapsulation alginate aerodynamically assisted jetting system Piscirickettsia salmonis antigen oral vaccine Medicine R |
description |
Salmon rickettsial septicaemia (SRS) is the infectious disease that produces the highest losses in the Chilean salmon industry. As a new strategy for the control of SRS outbreaks, in this study we evaluated the effect of alginate-encapsulated Piscirickettsia salmonis antigens (AEPSA) incorporated in the feed as an oral vaccine to induce the immune response in Atlantic salmon ( Salmo salar ). Fish were distributed into three vaccination groups (injectable, oral high dose, oral low dose). Feed intake and fish growth were recorded during the trial. The P. salmonis -specific IgM levels in blood plasma were measured by ELISA. Alginate microparticles containing the antigen were effectively incorporated in fish feed to produce the oral vaccine. Incorporation of AEPSA did not affect the palatability of the feed or the fish appetite. Furthermore, the oral vaccine did not have a negative effect on fish growth. Finally, the oral vaccine (high and low dose) produced an acquired immune response (IgM) similar to the injectable vaccine, generating a statistically significant increase in the IgM levels at 840-degree days for both experimental groups. These findings suggest that AEPSA incorporated in the feed can be an effective alternative to boost the immune response in Atlantic salmon ( S. salar ). |
format |
Article in Journal/Newspaper |
author |
Daniela Sotomayor-Gerding José Miguel Troncoso Alejandro Pino Felipe Almendras Mónica Rubilar Diaz |
author_facet |
Daniela Sotomayor-Gerding José Miguel Troncoso Alejandro Pino Felipe Almendras Mónica Rubilar Diaz |
author_sort |
Daniela Sotomayor-Gerding |
title |
Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens |
title_short |
Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens |
title_full |
Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens |
title_fullStr |
Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens |
title_full_unstemmed |
Assessing the Immune Response of Atlantic Salmon ( Salmo salar ) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens |
title_sort |
assessing the immune response of atlantic salmon ( salmo salar ) after the oral intake of alginate-encapsulated piscirickettsia salmonis antigens |
publisher |
MDPI AG |
publishDate |
2020 |
url |
https://doi.org/10.3390/vaccines8030450 https://doaj.org/article/5f801d28f67c42daa57ef308d3e14178 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Vaccines, Vol 8, Iss 450, p 450 (2020) |
op_relation |
https://www.mdpi.com/2076-393X/8/3/450 https://doaj.org/toc/2076-393X doi:10.3390/vaccines8030450 2076-393X https://doaj.org/article/5f801d28f67c42daa57ef308d3e14178 |
op_doi |
https://doi.org/10.3390/vaccines8030450 |
container_title |
Vaccines |
container_volume |
8 |
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3 |
container_start_page |
450 |
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1766361233641963520 |