Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae
Abstract INTRODUCTION: Aedes aegypti (L.) is the major vector of arboviruses that causes serious public health concerns in tropical and subtropical countries. METHODS: We examined the larvicidal activity of 1,2-diphenyldiselenide [(PhSe)2] and 1,2-bis(4-chlorophenyl) diselenide [(p-ClPhSe)2] and det...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
2020
|
Subjects: | |
Online Access: | https://doi.org/10.1590/0037-8682-0146-2020 https://doaj.org/article/5f4258663e0a44dd9326a953008b8238 |
id |
ftdoajarticles:oai:doaj.org/article:5f4258663e0a44dd9326a953008b8238 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:5f4258663e0a44dd9326a953008b8238 2023-05-15T15:02:35+02:00 Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae Sabrina Ketrin Targanski Janaina Rosa Sousa André Luiz Agnes Stein Marcos Antônio Soares 2020-12-01T00:00:00Z https://doi.org/10.1590/0037-8682-0146-2020 https://doaj.org/article/5f4258663e0a44dd9326a953008b8238 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100613&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0146-2020 https://doaj.org/article/5f4258663e0a44dd9326a953008b8238 Revista da Sociedade Brasileira de Medicina Tropical, Vol 54 (2020) Selenium 1,2-diphenyldiselenide 1,2-bis(4-chlorophenyl) diselenide Caenorhabditis elegans Chlorella vulgaris Galleria mellonela Arctic medicine. Tropical medicine RC955-962 article 2020 ftdoajarticles https://doi.org/10.1590/0037-8682-0146-2020 2022-12-30T23:24:25Z Abstract INTRODUCTION: Aedes aegypti (L.) is the major vector of arboviruses that causes serious public health concerns in tropical and subtropical countries. METHODS: We examined the larvicidal activity of 1,2-diphenyldiselenide [(PhSe)2] and 1,2-bis(4-chlorophenyl) diselenide [(p-ClPhSe)2] and determine its toxicity to different non-target organisms. RESULTS: (PhSe)2 and (p-ClPhSe)2 killed Ae. aegypti L3 larvae with LC50/24h values of 65.63 µM (20.48 mg/L) and 355.19 µM (135.33 mg/L), respectively. (PhSe)2 was not toxic to the four model organisms. CONCLUSIONS: (PhSe)2 is a larvicidal compound with selective action against Ae. aegypti larvae. The mechanisms of action of (PhSe)2 under field conditions remain to be investigated. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 54 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Selenium 1,2-diphenyldiselenide 1,2-bis(4-chlorophenyl) diselenide Caenorhabditis elegans Chlorella vulgaris Galleria mellonela Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Selenium 1,2-diphenyldiselenide 1,2-bis(4-chlorophenyl) diselenide Caenorhabditis elegans Chlorella vulgaris Galleria mellonela Arctic medicine. Tropical medicine RC955-962 Sabrina Ketrin Targanski Janaina Rosa Sousa André Luiz Agnes Stein Marcos Antônio Soares Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae |
topic_facet |
Selenium 1,2-diphenyldiselenide 1,2-bis(4-chlorophenyl) diselenide Caenorhabditis elegans Chlorella vulgaris Galleria mellonela Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: Aedes aegypti (L.) is the major vector of arboviruses that causes serious public health concerns in tropical and subtropical countries. METHODS: We examined the larvicidal activity of 1,2-diphenyldiselenide [(PhSe)2] and 1,2-bis(4-chlorophenyl) diselenide [(p-ClPhSe)2] and determine its toxicity to different non-target organisms. RESULTS: (PhSe)2 and (p-ClPhSe)2 killed Ae. aegypti L3 larvae with LC50/24h values of 65.63 µM (20.48 mg/L) and 355.19 µM (135.33 mg/L), respectively. (PhSe)2 was not toxic to the four model organisms. CONCLUSIONS: (PhSe)2 is a larvicidal compound with selective action against Ae. aegypti larvae. The mechanisms of action of (PhSe)2 under field conditions remain to be investigated. |
format |
Article in Journal/Newspaper |
author |
Sabrina Ketrin Targanski Janaina Rosa Sousa André Luiz Agnes Stein Marcos Antônio Soares |
author_facet |
Sabrina Ketrin Targanski Janaina Rosa Sousa André Luiz Agnes Stein Marcos Antônio Soares |
author_sort |
Sabrina Ketrin Targanski |
title |
Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae |
title_short |
Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae |
title_full |
Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae |
title_fullStr |
Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae |
title_full_unstemmed |
Selective activity of diselenides against Aedes aegypti (Diptera: Culicidae) larvae |
title_sort |
selective activity of diselenides against aedes aegypti (diptera: culicidae) larvae |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2020 |
url |
https://doi.org/10.1590/0037-8682-0146-2020 https://doaj.org/article/5f4258663e0a44dd9326a953008b8238 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 54 (2020) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100613&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0146-2020 https://doaj.org/article/5f4258663e0a44dd9326a953008b8238 |
op_doi |
https://doi.org/10.1590/0037-8682-0146-2020 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
54 |
_version_ |
1766334518507077632 |