Paracoccidioides brasiliensis: A MYCOLOGIC AND IMMUNOCHEMICAL STUDY OF TWO STRAINS

• Main Authors: Carlos da Silva LACAZ, Mônica Scarpelli Martinelli VIDAL, Elisabeth Maria HEINS-VACCARI, Natalina Takahashi de MELO, Gilda Maria Barbaro DEL NEGRO, Giovana Letícia Hernandez ARRIAGADA, Roseli dos Santos FREITAS
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1999
• Subjects: Paracoccidioides brasiliensis; Paracoccidioidomycosis; Immunochemical study; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doaj.org/article/5e6c9617fd284ad180aa0c331fda8470

The authors conducted a mycologic, immunochemical and molecular biology study on two strains of Paracoccidioides brasiliensis, one of them, called IBIÁ, isolated from soil in the municipality of IBIÁ (Minas Gerais) by Silva-Vergara et al. (l996,1998)20,21, and the other, BAT, cultivated from a human case of paracoccidioidomycosis in Ribeirão Preto (São Paulo/Brazil) by Freitas da Silva (l996)6. Both strains showed cotton-like (M) and yeast-like (Y) forms and were pathogenic for testicularly inoculated guinea pigs, producing granulomatous and/or suppurative orchitis. Immunochemically was demonstrated the presence of gp43 by double immunodiffusion, immunoelectrophoresis and immunoblotting.