Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar).
Salmonids (e.g. Atlantic salmon, Pacific salmon, and trouts) have a long legacy of genome duplication. In addition to three ancient genome duplications that all teleosts are thought to share, salmonids have had one additional genome duplication. We explored a methodology for untangling these duplica...
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ftdoajarticles:oai:doaj.org/article:5d72bcf6903642d9a97defa7538d5bef 2023-05-15T15:29:09+02:00 Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). Kris A Christensen William S Davidson 2017-01-01T00:00:00Z https://doi.org/10.1371/journal.pone.0173053 https://doaj.org/article/5d72bcf6903642d9a97defa7538d5bef EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5328387?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0173053 https://doaj.org/article/5d72bcf6903642d9a97defa7538d5bef PLoS ONE, Vol 12, Iss 2, p e0173053 (2017) Medicine R Science Q article 2017 ftdoajarticles https://doi.org/10.1371/journal.pone.0173053 2022-12-31T13:29:20Z Salmonids (e.g. Atlantic salmon, Pacific salmon, and trouts) have a long legacy of genome duplication. In addition to three ancient genome duplications that all teleosts are thought to share, salmonids have had one additional genome duplication. We explored a methodology for untangling these duplications from each other to better understand them in Atlantic salmon. In this methodology, homeologous regions (paralogous/duplicated genomic regions originating from a whole genome duplication) from the most recent genome duplication were assumed to have duplicated genes at greater density and have greater sequence similarity. This assumption was used to differentiate duplicated gene pairs in Atlantic salmon that are either from the most recent genome duplication or from earlier duplications. From a comparison with multiple vertebrate species, it is clear that Atlantic salmon have retained more duplicated genes from ancient genome duplications than other vertebrates--often at higher density in the genome and containing fewer synonymous mutations. It may be that polysomic inheritance is the mechanism responsible for maintaining ancient gene duplicates in salmonids. Polysomic inheritance (when multiple chromosomes pair during meiosis) is thought to be relatively common in salmonids compared to other vertebrate species. These findings illuminate how genome duplications may not only increase the number of duplicated genes, but may also be involved in the maintenance of them from previous genome duplications as well. Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles Pacific PLOS ONE 12 2 e0173053 |
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Medicine R Science Q |
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Medicine R Science Q Kris A Christensen William S Davidson Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). |
topic_facet |
Medicine R Science Q |
description |
Salmonids (e.g. Atlantic salmon, Pacific salmon, and trouts) have a long legacy of genome duplication. In addition to three ancient genome duplications that all teleosts are thought to share, salmonids have had one additional genome duplication. We explored a methodology for untangling these duplications from each other to better understand them in Atlantic salmon. In this methodology, homeologous regions (paralogous/duplicated genomic regions originating from a whole genome duplication) from the most recent genome duplication were assumed to have duplicated genes at greater density and have greater sequence similarity. This assumption was used to differentiate duplicated gene pairs in Atlantic salmon that are either from the most recent genome duplication or from earlier duplications. From a comparison with multiple vertebrate species, it is clear that Atlantic salmon have retained more duplicated genes from ancient genome duplications than other vertebrates--often at higher density in the genome and containing fewer synonymous mutations. It may be that polysomic inheritance is the mechanism responsible for maintaining ancient gene duplicates in salmonids. Polysomic inheritance (when multiple chromosomes pair during meiosis) is thought to be relatively common in salmonids compared to other vertebrate species. These findings illuminate how genome duplications may not only increase the number of duplicated genes, but may also be involved in the maintenance of them from previous genome duplications as well. |
format |
Article in Journal/Newspaper |
author |
Kris A Christensen William S Davidson |
author_facet |
Kris A Christensen William S Davidson |
author_sort |
Kris A Christensen |
title |
Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). |
title_short |
Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). |
title_full |
Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). |
title_fullStr |
Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). |
title_full_unstemmed |
Autopolyploidy genome duplication preserves other ancient genome duplications in Atlantic salmon (Salmo salar). |
title_sort |
autopolyploidy genome duplication preserves other ancient genome duplications in atlantic salmon (salmo salar). |
publisher |
Public Library of Science (PLoS) |
publishDate |
2017 |
url |
https://doi.org/10.1371/journal.pone.0173053 https://doaj.org/article/5d72bcf6903642d9a97defa7538d5bef |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
PLoS ONE, Vol 12, Iss 2, p e0173053 (2017) |
op_relation |
http://europepmc.org/articles/PMC5328387?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0173053 https://doaj.org/article/5d72bcf6903642d9a97defa7538d5bef |
op_doi |
https://doi.org/10.1371/journal.pone.0173053 |
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PLOS ONE |
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12 |
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2 |
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e0173053 |
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