Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia
Abstract Background Loss to follow-up (LTFU) is a major public health problem to antiretroviral therapy (ART) programs in sub-Saharan Africa. Failure to account for patients’ LTFU outcomes (self-transfers and restarts) can result in inaccurate reporting of retention in care. In Ethiopia, specificall...
Published in: | Tropical Medicine and Health |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2019
|
Subjects: | |
Online Access: | https://doi.org/10.1186/s41182-019-0181-6 https://doaj.org/article/5c8e3785104c43f4ac2bc92a55eb6962 |
id |
ftdoajarticles:oai:doaj.org/article:5c8e3785104c43f4ac2bc92a55eb6962 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:5c8e3785104c43f4ac2bc92a55eb6962 2023-05-15T15:16:15+02:00 Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia Moges Agazhe Assemie Cheru Tesema Leshargie Pammla Petrucka 2019-11-01T00:00:00Z https://doi.org/10.1186/s41182-019-0181-6 https://doaj.org/article/5c8e3785104c43f4ac2bc92a55eb6962 EN eng BMC http://link.springer.com/article/10.1186/s41182-019-0181-6 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-019-0181-6 1349-4147 https://doaj.org/article/5c8e3785104c43f4ac2bc92a55eb6962 Tropical Medicine and Health, Vol 47, Iss 1, Pp 1-6 (2019) Antiretroviral therapy Loss to follow-up Mortality ART tracing Cotrimoxazole preventive therapy Ethiopia Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1186/s41182-019-0181-6 2022-12-31T05:39:47Z Abstract Background Loss to follow-up (LTFU) is a major public health problem to antiretroviral therapy (ART) programs in sub-Saharan Africa. Failure to account for patients’ LTFU outcomes (self-transfers and restarts) can result in inaccurate reporting of retention in care. In Ethiopia, specifically in the Benishangule Gumuz region, high LTFU reported patients, who were not assessed for their outcomes, are identified as a gap. Therefore, our objective was to determine the outcomes (alive or dead) of patients lost to follow-up (LTFU) from ART and identify factors associated with successful tracing and mortality of these patients. Results The proportion of successful tracing was 75.5% (249 of 330). Among the traced patients (n = 249), 22.9% were deceased, 47.8% were on ART, and 29.3% had discontinued treatment. However, the remaining untraceable patients were not locatable due to wrong addresses (53.1%), change of residence (29.6%), and/or lack of functional phone contact (17.3%). Some (32.9%) of the patients discontinued because of negative test results, others (21.9%) for spiritual reasons or side effects (28.8%), and the remaining (16.4%) for other reasons. Tracing using phone numbers (AOR = 2.97, 95% CI 1.57–5.59) and existing long-term follow-up period for ART (AOR = 2.13, 95% CI 1.17–3.88) were strong predictors of successful tracing while not receiving cotrimoxazole preventive therapy (CPT) (AOR = 2.59, 95% CI 1.22–5.39) is a predictor for mortality of patients post-LTFU. Conclusion ART programs need to retain current contact information of patients or guardians/friends for tracing. Having phone contact numbers and prolonged lengths of compliance with ART are predictors of successful tracing, while lack of cotrimoxazole preventive therapy is a predictor of mortality. Early tracing of beginners (newly admitted recipients) and updating their detailed information at each follow-up visit is essential. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Medicine and Health 47 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Antiretroviral therapy Loss to follow-up Mortality ART tracing Cotrimoxazole preventive therapy Ethiopia Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Antiretroviral therapy Loss to follow-up Mortality ART tracing Cotrimoxazole preventive therapy Ethiopia Arctic medicine. Tropical medicine RC955-962 Moges Agazhe Assemie Cheru Tesema Leshargie Pammla Petrucka Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia |
topic_facet |
Antiretroviral therapy Loss to follow-up Mortality ART tracing Cotrimoxazole preventive therapy Ethiopia Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Loss to follow-up (LTFU) is a major public health problem to antiretroviral therapy (ART) programs in sub-Saharan Africa. Failure to account for patients’ LTFU outcomes (self-transfers and restarts) can result in inaccurate reporting of retention in care. In Ethiopia, specifically in the Benishangule Gumuz region, high LTFU reported patients, who were not assessed for their outcomes, are identified as a gap. Therefore, our objective was to determine the outcomes (alive or dead) of patients lost to follow-up (LTFU) from ART and identify factors associated with successful tracing and mortality of these patients. Results The proportion of successful tracing was 75.5% (249 of 330). Among the traced patients (n = 249), 22.9% were deceased, 47.8% were on ART, and 29.3% had discontinued treatment. However, the remaining untraceable patients were not locatable due to wrong addresses (53.1%), change of residence (29.6%), and/or lack of functional phone contact (17.3%). Some (32.9%) of the patients discontinued because of negative test results, others (21.9%) for spiritual reasons or side effects (28.8%), and the remaining (16.4%) for other reasons. Tracing using phone numbers (AOR = 2.97, 95% CI 1.57–5.59) and existing long-term follow-up period for ART (AOR = 2.13, 95% CI 1.17–3.88) were strong predictors of successful tracing while not receiving cotrimoxazole preventive therapy (CPT) (AOR = 2.59, 95% CI 1.22–5.39) is a predictor for mortality of patients post-LTFU. Conclusion ART programs need to retain current contact information of patients or guardians/friends for tracing. Having phone contact numbers and prolonged lengths of compliance with ART are predictors of successful tracing, while lack of cotrimoxazole preventive therapy is a predictor of mortality. Early tracing of beginners (newly admitted recipients) and updating their detailed information at each follow-up visit is essential. |
format |
Article in Journal/Newspaper |
author |
Moges Agazhe Assemie Cheru Tesema Leshargie Pammla Petrucka |
author_facet |
Moges Agazhe Assemie Cheru Tesema Leshargie Pammla Petrucka |
author_sort |
Moges Agazhe Assemie |
title |
Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia |
title_short |
Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia |
title_full |
Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia |
title_fullStr |
Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia |
title_full_unstemmed |
Outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in Pawi Hospital, Northwest Ethiopia |
title_sort |
outcomes and factors affecting mortality and successful tracing among patients lost to follow-up from antiretroviral therapy in pawi hospital, northwest ethiopia |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s41182-019-0181-6 https://doaj.org/article/5c8e3785104c43f4ac2bc92a55eb6962 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 47, Iss 1, Pp 1-6 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s41182-019-0181-6 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-019-0181-6 1349-4147 https://doaj.org/article/5c8e3785104c43f4ac2bc92a55eb6962 |
op_doi |
https://doi.org/10.1186/s41182-019-0181-6 |
container_title |
Tropical Medicine and Health |
container_volume |
47 |
container_issue |
1 |
_version_ |
1766346533350932480 |