The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India
Objective: To document the various clinical manifestations, lab parameters, complications and outcomes of Falciparum Malaria. The above data would be correlated with the parasitic index to deduce whether it would be an effective measure of the same. Methods: This was a prospective study among 183 in...
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ftdoajarticles:oai:doaj.org/article:5c6259b134574a82ad3a4a5d08263d2c 2023-05-15T15:11:01+02:00 The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India Mary Anne Poovathingal Shivashankara Kaniyoor Nagiri Nagaraja 2014-05-01T00:00:00Z https://doi.org/10.12980/APJTB.4.2014C1139 https://doaj.org/article/5c6259b134574a82ad3a4a5d08263d2c EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115302495 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.2014C1139 https://doaj.org/article/5c6259b134574a82ad3a4a5d08263d2c Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss S1, Pp S81-S86 (2014) Falciparum malaria Severe malaria Parasitic index Complications of malaria ESR and cerebral malaria Renal failure in malaria Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.12980/APJTB.4.2014C1139 2022-12-31T02:53:57Z Objective: To document the various clinical manifestations, lab parameters, complications and outcomes of Falciparum Malaria. The above data would be correlated with the parasitic index to deduce whether it would be an effective measure of the same. Methods: This was a prospective study among 183 inpatients aged above 18 from Kasturba Hospital, Manipal from May 2009 to January 2011. Ethical clearance was taken. Statistical analysis was done with the independent paired t test, linear correlation and Chi square test using SPSS 16. Results: In this study 78% cases were males. Most cases occurred during the monsoons. Fever was the major presentation with others being jaundice, vomiting and head ache. 50.8 % had complications, including hepatic dysfunction (40.9%), renal failure (19.13%), shock (7%), altered sensorium (9%), ARDS (3.27%) and severe anemia (1.63%). Hypoglycemia and gram negative sepsis were rare. Parasitic index, renal parameters and death were correlating positively. ESR was significantly related (P<0.003) to complications and not to cerebral malaria. There were 12 mortalities out of which 9 were due to MODS and 3 due to ARDS. Conclusions: 50.8% cases conformed to the WHO definition of severe malaria indicating most present with complications. High parasite index and abnormal renal function are predictors of mortality and complications. Early diagnosis, anticipation of complications, close monitoring and combination therapy to over come drug resistance helps to contain the extent of mortality. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 S81 S86 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Falciparum malaria Severe malaria Parasitic index Complications of malaria ESR and cerebral malaria Renal failure in malaria Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Falciparum malaria Severe malaria Parasitic index Complications of malaria ESR and cerebral malaria Renal failure in malaria Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Mary Anne Poovathingal Shivashankara Kaniyoor Nagiri Nagaraja The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India |
topic_facet |
Falciparum malaria Severe malaria Parasitic index Complications of malaria ESR and cerebral malaria Renal failure in malaria Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To document the various clinical manifestations, lab parameters, complications and outcomes of Falciparum Malaria. The above data would be correlated with the parasitic index to deduce whether it would be an effective measure of the same. Methods: This was a prospective study among 183 inpatients aged above 18 from Kasturba Hospital, Manipal from May 2009 to January 2011. Ethical clearance was taken. Statistical analysis was done with the independent paired t test, linear correlation and Chi square test using SPSS 16. Results: In this study 78% cases were males. Most cases occurred during the monsoons. Fever was the major presentation with others being jaundice, vomiting and head ache. 50.8 % had complications, including hepatic dysfunction (40.9%), renal failure (19.13%), shock (7%), altered sensorium (9%), ARDS (3.27%) and severe anemia (1.63%). Hypoglycemia and gram negative sepsis were rare. Parasitic index, renal parameters and death were correlating positively. ESR was significantly related (P<0.003) to complications and not to cerebral malaria. There were 12 mortalities out of which 9 were due to MODS and 3 due to ARDS. Conclusions: 50.8% cases conformed to the WHO definition of severe malaria indicating most present with complications. High parasite index and abnormal renal function are predictors of mortality and complications. Early diagnosis, anticipation of complications, close monitoring and combination therapy to over come drug resistance helps to contain the extent of mortality. |
format |
Article in Journal/Newspaper |
author |
Mary Anne Poovathingal Shivashankara Kaniyoor Nagiri Nagaraja |
author_facet |
Mary Anne Poovathingal Shivashankara Kaniyoor Nagiri Nagaraja |
author_sort |
Mary Anne Poovathingal |
title |
The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India |
title_short |
The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India |
title_full |
The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India |
title_fullStr |
The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India |
title_full_unstemmed |
The emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of India |
title_sort |
emerging trends of falciparum malaria: a study from a tertiary centre in an endemic area of india |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.12980/APJTB.4.2014C1139 https://doaj.org/article/5c6259b134574a82ad3a4a5d08263d2c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss S1, Pp S81-S86 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115302495 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.2014C1139 https://doaj.org/article/5c6259b134574a82ad3a4a5d08263d2c |
op_doi |
https://doi.org/10.12980/APJTB.4.2014C1139 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_start_page |
S81 |
op_container_end_page |
S86 |
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1766341934169718784 |