Patterns of homozygosity in insular and continental goat breeds
Abstract Background Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and Africa...
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ftdoajarticles:oai:doaj.org/article:5c5f02f079d244c4b3a85dd94d236715 2023-05-15T16:48:48+02:00 Patterns of homozygosity in insular and continental goat breeds Taina F. Cardoso Marcel Amills Francesca Bertolini Max Rothschild Gabriele Marras Geert Boink Jordi Jordana Juan Capote Sean Carolan Jón H. Hallsson Juha Kantanen Agueda Pons Johannes A. Lenstra The AdaptMap Consortium 2018-11-01T00:00:00Z https://doi.org/10.1186/s12711-018-0425-7 https://doaj.org/article/5c5f02f079d244c4b3a85dd94d236715 DE EN FR ger eng fre BMC http://link.springer.com/article/10.1186/s12711-018-0425-7 https://doaj.org/toc/1297-9686 doi:10.1186/s12711-018-0425-7 1297-9686 https://doaj.org/article/5c5f02f079d244c4b3a85dd94d236715 Genetics Selection Evolution, Vol 50, Iss 1, Pp 1-11 (2018) Animal culture SF1-1100 Genetics QH426-470 article 2018 ftdoajarticles https://doi.org/10.1186/s12711-018-0425-7 2022-12-31T14:30:33Z Abstract Background Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. Results Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and F ROH values (P value < 0.05). Goats from Mediterranean islands represent a more complex case because certain populations displayed a significantly increased level of homozygosity (e.g. Girgentana) and others did not (e.g. Corse and Sarda). Correlations of number and total length of ROH for insular goat populations with the distance between islands and the nearest continental locations revealed an effect of extremely long distances on the patterns of homozygosity. Conclusions These results indicate that the effects of insularization on the patterns of homozygosity are variable. Goats raised in Madagascar, Iceland, Ireland (Bilberry and Arran) and La Palma, show high levels of homozygosity, whereas those bred in Mediterranean islands display patterns of homozygosity that are similar to those found in continental populations. These results indicate that the diversity of insular goat populations is modulated by multiple factors such as geographic distribution, population size, demographic history, trading and breed management. Article in Journal/Newspaper Iceland Directory of Open Access Journals: DOAJ Articles Genetics Selection Evolution 50 1 |
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German English French |
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Animal culture SF1-1100 Genetics QH426-470 |
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Animal culture SF1-1100 Genetics QH426-470 Taina F. Cardoso Marcel Amills Francesca Bertolini Max Rothschild Gabriele Marras Geert Boink Jordi Jordana Juan Capote Sean Carolan Jón H. Hallsson Juha Kantanen Agueda Pons Johannes A. Lenstra The AdaptMap Consortium Patterns of homozygosity in insular and continental goat breeds |
topic_facet |
Animal culture SF1-1100 Genetics QH426-470 |
description |
Abstract Background Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. Results Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and F ROH values (P value < 0.05). Goats from Mediterranean islands represent a more complex case because certain populations displayed a significantly increased level of homozygosity (e.g. Girgentana) and others did not (e.g. Corse and Sarda). Correlations of number and total length of ROH for insular goat populations with the distance between islands and the nearest continental locations revealed an effect of extremely long distances on the patterns of homozygosity. Conclusions These results indicate that the effects of insularization on the patterns of homozygosity are variable. Goats raised in Madagascar, Iceland, Ireland (Bilberry and Arran) and La Palma, show high levels of homozygosity, whereas those bred in Mediterranean islands display patterns of homozygosity that are similar to those found in continental populations. These results indicate that the diversity of insular goat populations is modulated by multiple factors such as geographic distribution, population size, demographic history, trading and breed management. |
format |
Article in Journal/Newspaper |
author |
Taina F. Cardoso Marcel Amills Francesca Bertolini Max Rothschild Gabriele Marras Geert Boink Jordi Jordana Juan Capote Sean Carolan Jón H. Hallsson Juha Kantanen Agueda Pons Johannes A. Lenstra The AdaptMap Consortium |
author_facet |
Taina F. Cardoso Marcel Amills Francesca Bertolini Max Rothschild Gabriele Marras Geert Boink Jordi Jordana Juan Capote Sean Carolan Jón H. Hallsson Juha Kantanen Agueda Pons Johannes A. Lenstra The AdaptMap Consortium |
author_sort |
Taina F. Cardoso |
title |
Patterns of homozygosity in insular and continental goat breeds |
title_short |
Patterns of homozygosity in insular and continental goat breeds |
title_full |
Patterns of homozygosity in insular and continental goat breeds |
title_fullStr |
Patterns of homozygosity in insular and continental goat breeds |
title_full_unstemmed |
Patterns of homozygosity in insular and continental goat breeds |
title_sort |
patterns of homozygosity in insular and continental goat breeds |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s12711-018-0425-7 https://doaj.org/article/5c5f02f079d244c4b3a85dd94d236715 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Genetics Selection Evolution, Vol 50, Iss 1, Pp 1-11 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s12711-018-0425-7 https://doaj.org/toc/1297-9686 doi:10.1186/s12711-018-0425-7 1297-9686 https://doaj.org/article/5c5f02f079d244c4b3a85dd94d236715 |
op_doi |
https://doi.org/10.1186/s12711-018-0425-7 |
container_title |
Genetics Selection Evolution |
container_volume |
50 |
container_issue |
1 |
_version_ |
1766038897319477248 |