Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects
Abstract INTRODUCTION: Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate the incidence of and risk factors associated with central venous catheter-related infections in patients undergoing hemodialysis, and to identify and c...
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ftdoajarticles:oai:doaj.org/article:5c45fd891a38489eb6323053abdb4a47 2023-05-15T15:10:27+02:00 Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects Mayra Gonçalves Menegueti Natália Cristina Betoni Fernando Bellissimo-Rodrigues Elen Almeida Romão https://doi.org/10.1590/0037-8682-0438-2017 https://doaj.org/article/5c45fd891a38489eb6323053abdb4a47 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000600783&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0438-2017 https://doaj.org/article/5c45fd891a38489eb6323053abdb4a47 Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 6, Pp 783-787 Bloodstream infection Hemodialysis Resistant microorganisms Arctic medicine. Tropical medicine RC955-962 article ftdoajarticles https://doi.org/10.1590/0037-8682-0438-2017 2022-12-30T21:27:18Z Abstract INTRODUCTION: Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate the incidence of and risk factors associated with central venous catheter-related infections in patients undergoing hemodialysis, and to identify and characterize the type and antimicrobial susceptibility profiles of the primary microorganisms isolated during one year of follow-up. METHODS: A prospective cohort study was conducted in 2014 in a hemodialysis referral center. We included 200 outpatients with acute kidney injury who had no permanent venous access. A nurse assessed the patients for signs of infection three times per week during dressing changes. The clinicopathologic characteristics of patients with and without local or systemic infection were compared. RESULTS: Fifty-five episodes of catheter-related infections occurred in 43 (22%) patients; 38 (69%) were bloodstream infections and 17 (31%) were local infections. Thirty-two (75%) patients with infection had femoral vein catheter placement. In total, 6,240 hemodialysis sessions were performed; the rates of primary bloodstream and local infection were 6.1 and 2.7 episodes per 1,000 patients on daily dialysis, respectively. In the univariate analysis, diabetes was significantly associated with the development of infection, while level of education, ethnicity, age, and sex were not. Gram-negative bacteria were primarily isolated from blood culture specimens (55% of samples). Of the Gram-negative isolates, 56% were resistant to the carbapenems. CONCLUSIONS: We identified a high incidence of catheter-related infections caused by resistant microorganisms in patients undergoing hemodialysis via central venous catheters. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 50 6 783 787 |
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Directory of Open Access Journals: DOAJ Articles |
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Bloodstream infection Hemodialysis Resistant microorganisms Arctic medicine. Tropical medicine RC955-962 |
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Bloodstream infection Hemodialysis Resistant microorganisms Arctic medicine. Tropical medicine RC955-962 Mayra Gonçalves Menegueti Natália Cristina Betoni Fernando Bellissimo-Rodrigues Elen Almeida Romão Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
topic_facet |
Bloodstream infection Hemodialysis Resistant microorganisms Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate the incidence of and risk factors associated with central venous catheter-related infections in patients undergoing hemodialysis, and to identify and characterize the type and antimicrobial susceptibility profiles of the primary microorganisms isolated during one year of follow-up. METHODS: A prospective cohort study was conducted in 2014 in a hemodialysis referral center. We included 200 outpatients with acute kidney injury who had no permanent venous access. A nurse assessed the patients for signs of infection three times per week during dressing changes. The clinicopathologic characteristics of patients with and without local or systemic infection were compared. RESULTS: Fifty-five episodes of catheter-related infections occurred in 43 (22%) patients; 38 (69%) were bloodstream infections and 17 (31%) were local infections. Thirty-two (75%) patients with infection had femoral vein catheter placement. In total, 6,240 hemodialysis sessions were performed; the rates of primary bloodstream and local infection were 6.1 and 2.7 episodes per 1,000 patients on daily dialysis, respectively. In the univariate analysis, diabetes was significantly associated with the development of infection, while level of education, ethnicity, age, and sex were not. Gram-negative bacteria were primarily isolated from blood culture specimens (55% of samples). Of the Gram-negative isolates, 56% were resistant to the carbapenems. CONCLUSIONS: We identified a high incidence of catheter-related infections caused by resistant microorganisms in patients undergoing hemodialysis via central venous catheters. |
format |
Article in Journal/Newspaper |
author |
Mayra Gonçalves Menegueti Natália Cristina Betoni Fernando Bellissimo-Rodrigues Elen Almeida Romão |
author_facet |
Mayra Gonçalves Menegueti Natália Cristina Betoni Fernando Bellissimo-Rodrigues Elen Almeida Romão |
author_sort |
Mayra Gonçalves Menegueti |
title |
Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
title_short |
Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
title_full |
Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
title_fullStr |
Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
title_full_unstemmed |
Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
title_sort |
central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
url |
https://doi.org/10.1590/0037-8682-0438-2017 https://doaj.org/article/5c45fd891a38489eb6323053abdb4a47 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 6, Pp 783-787 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000600783&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0438-2017 https://doaj.org/article/5c45fd891a38489eb6323053abdb4a47 |
op_doi |
https://doi.org/10.1590/0037-8682-0438-2017 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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