Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia
Streptococcus pneumoniae is one of the principal causal agents of acute respiratory infection (ARI) in children, and its resistance to antibiotics has increased worldwide. This study examined the patterns of susceptibility to antibiotics of S. pneumoniae that had colonized the upper respiratory trac...
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Pan American Health Organization
1997
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ftdoajarticles:oai:doaj.org/article:5bd1850d90534d4ab41e2c3522ff61db 2023-05-15T15:07:01+02:00 Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia Aura Lucía Leal Elizabeth Castañeda 1997-10-01T00:00:00Z https://doi.org/10.1590/s1020-49891997001000005 https://doaj.org/article/5bd1850d90534d4ab41e2c3522ff61db EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49891997001000005&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49891997001000005 https://doaj.org/article/5bd1850d90534d4ab41e2c3522ff61db Revista Panamericana de Salud Pública, Vol 2, Iss 4, Pp 253-259 (1997) Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 1997 ftdoajarticles https://doi.org/10.1590/s1020-49891997001000005 2022-12-31T10:46:33Z Streptococcus pneumoniae is one of the principal causal agents of acute respiratory infection (ARI) in children, and its resistance to antibiotics has increased worldwide. This study examined the patterns of susceptibility to antibiotics of S. pneumoniae that had colonized the upper respiratory tract of 272 children hospitalized for pneumonia in two hospitals in Santafé de Bogotá. S. pneumoniae was isolated from 114 patients (42%). Diminished susceptibility to penicillin was noted in 19 isolates (17%), with 12 (11%) having an intermediate level of sensitivity and 7 (6%) showing outright resistance. Only 1 of the 19 isolates resistant to penicillin also showed resistance to ceftriaxone. There was diminished sensitivity to erythromycin in 3 isolates (3%), to chloramphenicol in 6 (5%), and to co-trimoxazole (trimethoprim + sulfamethoxazole) in 46 (40%). Resistance to multiple drugs was found in 7 isolates (6%). The most commonly encountered penicillin-resistant serotype was 23F (68.4%). An association was observed between age, prior use of antibiotics, and colonization by S. pneumoniae with reduced penicillin sensitivity or multiple-drug resistance. This study confirmed the presence of antibiotic-resistant S. pneumoniae in Colombia and highlights the importance of the rational use of antibiotics and of the implementation of epidemiologic surveillance for this agent. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Ari ENVELOPE(147.813,147.813,59.810,59.810) Revista Panamericana de Salud Pública 2 4 253 259 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English Spanish Portuguese |
topic |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Aura Lucía Leal Elizabeth Castañeda Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia |
topic_facet |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Streptococcus pneumoniae is one of the principal causal agents of acute respiratory infection (ARI) in children, and its resistance to antibiotics has increased worldwide. This study examined the patterns of susceptibility to antibiotics of S. pneumoniae that had colonized the upper respiratory tract of 272 children hospitalized for pneumonia in two hospitals in Santafé de Bogotá. S. pneumoniae was isolated from 114 patients (42%). Diminished susceptibility to penicillin was noted in 19 isolates (17%), with 12 (11%) having an intermediate level of sensitivity and 7 (6%) showing outright resistance. Only 1 of the 19 isolates resistant to penicillin also showed resistance to ceftriaxone. There was diminished sensitivity to erythromycin in 3 isolates (3%), to chloramphenicol in 6 (5%), and to co-trimoxazole (trimethoprim + sulfamethoxazole) in 46 (40%). Resistance to multiple drugs was found in 7 isolates (6%). The most commonly encountered penicillin-resistant serotype was 23F (68.4%). An association was observed between age, prior use of antibiotics, and colonization by S. pneumoniae with reduced penicillin sensitivity or multiple-drug resistance. This study confirmed the presence of antibiotic-resistant S. pneumoniae in Colombia and highlights the importance of the rational use of antibiotics and of the implementation of epidemiologic surveillance for this agent. |
format |
Article in Journal/Newspaper |
author |
Aura Lucía Leal Elizabeth Castañeda |
author_facet |
Aura Lucía Leal Elizabeth Castañeda |
author_sort |
Aura Lucía Leal |
title |
Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia |
title_short |
Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia |
title_full |
Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia |
title_fullStr |
Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia |
title_full_unstemmed |
Antibiotic susceptibility of Streptococcus pneumoniae colonizing the nasopharynx of Colombian children with pneumonia |
title_sort |
antibiotic susceptibility of streptococcus pneumoniae colonizing the nasopharynx of colombian children with pneumonia |
publisher |
Pan American Health Organization |
publishDate |
1997 |
url |
https://doi.org/10.1590/s1020-49891997001000005 https://doaj.org/article/5bd1850d90534d4ab41e2c3522ff61db |
long_lat |
ENVELOPE(147.813,147.813,59.810,59.810) |
geographic |
Arctic Ari |
geographic_facet |
Arctic Ari |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 2, Iss 4, Pp 253-259 (1997) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49891997001000005&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49891997001000005 https://doaj.org/article/5bd1850d90534d4ab41e2c3522ff61db |
op_doi |
https://doi.org/10.1590/s1020-49891997001000005 |
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Revista Panamericana de Salud Pública |
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2 |
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253 |
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259 |
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