Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection
Information obtained from the routine application of hydatid immunodiagnostic techniques in different clinical situations over a seven-year period is presented. The Immunoelectrophoresis test was used until it was replaced by the simpler, more sensitive and equally specific arc 5 double diffusion (D...
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Universidade de São Paulo (USP)
1984
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Online Access: | https://doi.org/10.1590/S0036-46651984000200004 https://doaj.org/article/5b30a7c4d72746489c1502f27f2e4a88 |
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ftdoajarticles:oai:doaj.org/article:5b30a7c4d72746489c1502f27f2e4a88 2024-09-09T19:26:02+00:00 Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection V. M. Varela-diaz E. A. Coltorti 1984-04-01T00:00:00Z https://doi.org/10.1590/S0036-46651984000200004 https://doaj.org/article/5b30a7c4d72746489c1502f27f2e4a88 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651984000200004&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46651984000200004 https://doaj.org/article/5b30a7c4d72746489c1502f27f2e4a88 Revista do Instituto de Medicina Tropical de São Paulo, Vol 26, Iss 2, Pp 87-96 (1984) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1984 ftdoajarticles https://doi.org/10.1590/S0036-46651984000200004 2024-08-05T17:49:30Z Information obtained from the routine application of hydatid immunodiagnostic techniques in different clinical situations over a seven-year period is presented. The Immunoelectrophoresis test was used until it was replaced by the simpler, more sensitive and equally specific arc 5 double diffusion (DD5) test. Examination of sera from 1,888 patients with signs and/or symptoms compatible with hydatid disease revealed that the presurgical confirmation of Echinococcus granulosus infection is only obtained by detection of anti-antigen 5 antibodies. The latter were not found in 1,539 presumptive hydatidosis patients whose definitive diagnoses corresponded to other disease conditions. However, false positive latex agglutination test results were obtained in two cases. In all patients whose preoperative serum showed three or more uncharacteristic bands in the absence of anti-antigen 5 antibodies, hydatid cysts were found sur gically. DD5 testing of a fluid sample collected by puncture established its hydatid etiology. Post-operative monitoring of hydatidosis patients demonstrated that persistence of DD5-positivity two years after surgery established the presence of other cysts. Further evidence was obtained in patients with hydatid cysts in intrathoracic, abdominal or other locations associating cyst membrane integrity, antigen release and immunodiagnostic test positivity. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 26 2 87 96 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 V. M. Varela-diaz E. A. Coltorti Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Information obtained from the routine application of hydatid immunodiagnostic techniques in different clinical situations over a seven-year period is presented. The Immunoelectrophoresis test was used until it was replaced by the simpler, more sensitive and equally specific arc 5 double diffusion (DD5) test. Examination of sera from 1,888 patients with signs and/or symptoms compatible with hydatid disease revealed that the presurgical confirmation of Echinococcus granulosus infection is only obtained by detection of anti-antigen 5 antibodies. The latter were not found in 1,539 presumptive hydatidosis patients whose definitive diagnoses corresponded to other disease conditions. However, false positive latex agglutination test results were obtained in two cases. In all patients whose preoperative serum showed three or more uncharacteristic bands in the absence of anti-antigen 5 antibodies, hydatid cysts were found sur gically. DD5 testing of a fluid sample collected by puncture established its hydatid etiology. Post-operative monitoring of hydatidosis patients demonstrated that persistence of DD5-positivity two years after surgery established the presence of other cysts. Further evidence was obtained in patients with hydatid cysts in intrathoracic, abdominal or other locations associating cyst membrane integrity, antigen release and immunodiagnostic test positivity. |
format |
Article in Journal/Newspaper |
author |
V. M. Varela-diaz E. A. Coltorti |
author_facet |
V. M. Varela-diaz E. A. Coltorti |
author_sort |
V. M. Varela-diaz |
title |
Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
title_short |
Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
title_full |
Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
title_fullStr |
Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
title_full_unstemmed |
Immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
title_sort |
immunodiagnostic confirmation of hydatid disease in patients with a presumptive diagnosis of infection |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1984 |
url |
https://doi.org/10.1590/S0036-46651984000200004 https://doaj.org/article/5b30a7c4d72746489c1502f27f2e4a88 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 26, Iss 2, Pp 87-96 (1984) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651984000200004&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46651984000200004 https://doaj.org/article/5b30a7c4d72746489c1502f27f2e4a88 |
op_doi |
https://doi.org/10.1590/S0036-46651984000200004 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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26 |
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