Analysis of Opisthorchis felineus infection and liver and intrahepatic bile ducts cancer incidence rate in Russian Federation

• Published in: Bulletin of Siberian Medicine
• Main Authors: O. S. Fedorova, Y. V. Kovshirina, A. E. Kovshirina, M. M. Fedotova, I. A. Deev, F. I. Petrovskiy, A. V. Filimonov, A. I. Dmitrieva, L. A. Kudyakov, I. V. Saltykova, Е. В. Михалев, P. Odermatt, L. M. Ogorodova
• Format: Article in Journal/Newspaper
• Language: English; Russian
• Published: Siberian State Medical University (Tomsk) 2017
• Subjects: инвазия opisthorchis felineus; злокачественные новообразования гепатобилиарной системы; заболеваемость; эпидемиология; Medicine; R; khanty; nenets; Nenets Autonomous Okrug; Yamalo Nenets; Yamalo-Nenets Autonomous Okrug; Siberia
• Online Access: https://doi.org/10.20538/1682-0363-2016-5-147-158; https://doaj.org/article/5aeb5984f667418bbc6a783c344d7f69

The purpose of this paper is to perform the pilot review of the official medical statistics on reported Opisthorchis felineus (O. felineus) infection and liver and intrahepatic bile duct cancer in Russian Federation, covering the period 2011–2013.Materials and methods. Statistical data collected from 81 regions of Russia, reflecting the incidence of opisthorchiasis over a period from the 1st of January 2011 to the 31st of December 2013 was analyzed. The analysis of official health statistics of malignant hepatic lesions and intrahepatic bile duct was conducted in 82 regions of Russia over the same period. The data was obtained from the annual reports of the Russian center of information technologies and epidemiological studies in the field of oncology.Results. The average annual incidence of O. felineus was 24,7 ± 9,0 cases per 100,000 population. The highest incidence was observed in Khanty-Mansiysk Autonomous Okrug, Yamalo-Nenets Autonomous Okrug, Tyumen Oblast, Tomsk Oblast, Omsk Oblast and Novosibirsk Oblast. We did not observe any significant change in O. felineus infection rates within last 20 years. However, we found that infection incidence had increased in some geographical units of Western Siberia. The incidence of liver and intrahepatic bile duct cancers was 4,8 ± 0,2 cases per 100,000 population; the highest rate was reported in Far East regions, Siberia and Volgograd Oblast. This study documents the importance of opisthorchiasis in certain endemic areas and presents the best available data on associations between O. felineus infection and liver/intrahepatic bile duct cancers in endemic areas of Russian Federation.