Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018)
Relevance. Annual elevation of enterovirus infection (EVI) incidence in the Russian Federation as well as in the Sakhalin region determine a necessity of continuous surveillance involving molecular-genetic methods and phylogenetic analysis. Objective: to highlight epidemiological and molecular-genet...
Published in: | Epidemiology and Vaccinal Prevention |
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Language: | Russian |
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Numikom LLC
2019
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Online Access: | https://doi.org/10.31631/2073-3046-2019-18-5-33-41 https://doaj.org/article/59dc21d5fae84d6d866a6ee7f5ec779b |
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ftdoajarticles:oai:doaj.org/article:59dc21d5fae84d6d866a6ee7f5ec779b 2023-05-15T18:08:37+02:00 Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) E. Yu. Sapega L. V. Butakova O. E. Trotsenko O. A. Funtusova G. P. Kovtoniuk 2019-11-01T00:00:00Z https://doi.org/10.31631/2073-3046-2019-18-5-33-41 https://doaj.org/article/59dc21d5fae84d6d866a6ee7f5ec779b RU rus Numikom LLC https://www.epidemvac.ru/jour/article/view/833 https://doaj.org/toc/2073-3046 https://doaj.org/toc/2619-0494 2073-3046 2619-0494 doi:10.31631/2073-3046-2019-18-5-33-41 https://doaj.org/article/59dc21d5fae84d6d866a6ee7f5ec779b Эпидемиология и вакцинопрофилактика, Vol 18, Iss 5, Pp 33-41 (2019) энтеровирусная инфекция энтеровирус эпидемиологический анализ групповая заболеваемость молекулярно-генетические исследования сахалинская область Epistemology. Theory of knowledge BD143-237 article 2019 ftdoajarticles https://doi.org/10.31631/2073-3046-2019-18-5-33-41 2023-03-19T01:41:16Z Relevance. Annual elevation of enterovirus infection (EVI) incidence in the Russian Federation as well as in the Sakhalin region determine a necessity of continuous surveillance involving molecular-genetic methods and phylogenetic analysis. Objective: to highlight epidemiological and molecular-genetic peculiarities of EVI in the Sakhalin region during 2016-2018 years. Materials and methods. Analysis of enterovirus incidence were based on official statistical reporting forms. The structure of enterovirus types was evaluated by means of molecular methods and followed by phylogenetic analysis. Results and discussion. A deterioration of epidemic situation concerning EVI that began in 2016 in the Sakhalin region included elevation of incidence and registration of enterovirus outbreaks in childcare facilities triggered by introduction of new enterovirus types or those that were not circulating for a long time suchas Coxsackievirus A-6, Coxsackievirus A-10, Coxsackievirus A-16, ECHO-9. The phylogenetic analysis of Coxsackievirus A-16 detected in the Sakhalin region revealed their similarities with two genovariants of B genogroup (В1а и В1b) that were continuously circulating in Russia and China. In addition, enterovirus ECHO-9 that was also circulating in other constituent entities of the Russian Federation was isolated in Sakhalin region from patients suffering from viral meningitis including two children from two different infection cites of EVI group incidence. Conclusion. An unfavorable epidemic situation concerning EVI was revealed in the Sakhalin region during the last three years of surveillance. It was caused by introduction and further spread among population of Coxsackieviruses A-6, 10, 16 and ECHO-9 that presumably have Russian or foreign origin. Article in Journal/Newspaper Sakhalin Directory of Open Access Journals: DOAJ Articles Epidemiology and Vaccinal Prevention 18 5 33 41 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
Russian |
topic |
энтеровирусная инфекция энтеровирус эпидемиологический анализ групповая заболеваемость молекулярно-генетические исследования сахалинская область Epistemology. Theory of knowledge BD143-237 |
spellingShingle |
энтеровирусная инфекция энтеровирус эпидемиологический анализ групповая заболеваемость молекулярно-генетические исследования сахалинская область Epistemology. Theory of knowledge BD143-237 E. Yu. Sapega L. V. Butakova O. E. Trotsenko O. A. Funtusova G. P. Kovtoniuk Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) |
topic_facet |
энтеровирусная инфекция энтеровирус эпидемиологический анализ групповая заболеваемость молекулярно-генетические исследования сахалинская область Epistemology. Theory of knowledge BD143-237 |
description |
Relevance. Annual elevation of enterovirus infection (EVI) incidence in the Russian Federation as well as in the Sakhalin region determine a necessity of continuous surveillance involving molecular-genetic methods and phylogenetic analysis. Objective: to highlight epidemiological and molecular-genetic peculiarities of EVI in the Sakhalin region during 2016-2018 years. Materials and methods. Analysis of enterovirus incidence were based on official statistical reporting forms. The structure of enterovirus types was evaluated by means of molecular methods and followed by phylogenetic analysis. Results and discussion. A deterioration of epidemic situation concerning EVI that began in 2016 in the Sakhalin region included elevation of incidence and registration of enterovirus outbreaks in childcare facilities triggered by introduction of new enterovirus types or those that were not circulating for a long time suchas Coxsackievirus A-6, Coxsackievirus A-10, Coxsackievirus A-16, ECHO-9. The phylogenetic analysis of Coxsackievirus A-16 detected in the Sakhalin region revealed their similarities with two genovariants of B genogroup (В1а и В1b) that were continuously circulating in Russia and China. In addition, enterovirus ECHO-9 that was also circulating in other constituent entities of the Russian Federation was isolated in Sakhalin region from patients suffering from viral meningitis including two children from two different infection cites of EVI group incidence. Conclusion. An unfavorable epidemic situation concerning EVI was revealed in the Sakhalin region during the last three years of surveillance. It was caused by introduction and further spread among population of Coxsackieviruses A-6, 10, 16 and ECHO-9 that presumably have Russian or foreign origin. |
format |
Article in Journal/Newspaper |
author |
E. Yu. Sapega L. V. Butakova O. E. Trotsenko O. A. Funtusova G. P. Kovtoniuk |
author_facet |
E. Yu. Sapega L. V. Butakova O. E. Trotsenko O. A. Funtusova G. P. Kovtoniuk |
author_sort |
E. Yu. Sapega |
title |
Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) |
title_short |
Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) |
title_full |
Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) |
title_fullStr |
Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) |
title_full_unstemmed |
Aspects of Enterovirus Infection Molecular Epidemiology in Sakhalin Region (during years 2016–2018) |
title_sort |
aspects of enterovirus infection molecular epidemiology in sakhalin region (during years 2016–2018) |
publisher |
Numikom LLC |
publishDate |
2019 |
url |
https://doi.org/10.31631/2073-3046-2019-18-5-33-41 https://doaj.org/article/59dc21d5fae84d6d866a6ee7f5ec779b |
genre |
Sakhalin |
genre_facet |
Sakhalin |
op_source |
Эпидемиология и вакцинопрофилактика, Vol 18, Iss 5, Pp 33-41 (2019) |
op_relation |
https://www.epidemvac.ru/jour/article/view/833 https://doaj.org/toc/2073-3046 https://doaj.org/toc/2619-0494 2073-3046 2619-0494 doi:10.31631/2073-3046-2019-18-5-33-41 https://doaj.org/article/59dc21d5fae84d6d866a6ee7f5ec779b |
op_doi |
https://doi.org/10.31631/2073-3046-2019-18-5-33-41 |
container_title |
Epidemiology and Vaccinal Prevention |
container_volume |
18 |
container_issue |
5 |
container_start_page |
33 |
op_container_end_page |
41 |
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1766180921769197568 |