Source attribution of human echinococcosis: A systematic review and meta-analysis.
Background A substantial proportion of echinococcosis transmission to humans via contamination of food has been assumed. However, the relative importance of food as a transmission vehicle has previously been estimated through expert opinion rather than empirical data. Objective To find and evaluate...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0008382 https://doaj.org/article/59a4e4ba6ece440a9c8e5177cfc95baa |
id |
ftdoajarticles:oai:doaj.org/article:59a4e4ba6ece440a9c8e5177cfc95baa |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:59a4e4ba6ece440a9c8e5177cfc95baa 2023-05-15T15:16:25+02:00 Source attribution of human echinococcosis: A systematic review and meta-analysis. Paul R Torgerson Lucy J Robertson Heidi L Enemark Junwei Foehr Joke W B van der Giessen Christian M O Kapel Ivana Klun Chiara Trevisan 2020-06-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008382 https://doaj.org/article/59a4e4ba6ece440a9c8e5177cfc95baa EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008382 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008382 https://doaj.org/article/59a4e4ba6ece440a9c8e5177cfc95baa PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008382 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008382 2022-12-31T10:07:30Z Background A substantial proportion of echinococcosis transmission to humans via contamination of food has been assumed. However, the relative importance of food as a transmission vehicle has previously been estimated through expert opinion rather than empirical data. Objective To find and evaluate empirical data that could be used to estimate the source attribution of echinococcosis, in particular the proportion that is transmitted through contaminated food. Methods A systematic review was undertaken to identify reports on the risk factors for human cystic (CE) and alveolar (AE) echinococcosis. Data bases searched included PubMed, Scopus, Web of Knowledge, Cab Direct, Science Direct, Google Scholar, eLIBRARY.RU, CyberLeninka, CNKI and VIP. Search terms included Echinococc*, hydatid, epidemiology, logistic regression, risk factors, odds ratio, relative risk, risk factors. Reports, including grey literature where available, that had suitable data were selected and data were extracted. The main pathways of transmission were hypothesised to be contact with the definitive host, contaminated water, contaminated food and contaminated environment (other than food). For each study the attributable fraction for these potential sources of infection was calculated from the data presented. A meta-analysis was then undertaken to obtain pooled estimates for the relative contribution of these transmission pathways. Results Data from 28 cross-sectional studies and 14 case-control studies were extracted. There was strong evidence for transmission by direct contact with dogs for both CE and AE. The estimated attributable fractions were 26.1% (CI 13.8%-39.6%) and 34.4% (CI 20.7% -48.2%) respectively. Transmission through contaminated water was estimated to be responsible for approximately 29.4% (CI 12.1%-51.7%) for CE and 24.8% (CI 10.6% to 42.6%) for AE. Contaminated food may be responsible for approximately 23.4% of CE cases (CI 2.1%-47.3%). Globally, there was insufficient evidence to conclude AE can be transmitted by food, ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 6 e0008382 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Paul R Torgerson Lucy J Robertson Heidi L Enemark Junwei Foehr Joke W B van der Giessen Christian M O Kapel Ivana Klun Chiara Trevisan Source attribution of human echinococcosis: A systematic review and meta-analysis. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background A substantial proportion of echinococcosis transmission to humans via contamination of food has been assumed. However, the relative importance of food as a transmission vehicle has previously been estimated through expert opinion rather than empirical data. Objective To find and evaluate empirical data that could be used to estimate the source attribution of echinococcosis, in particular the proportion that is transmitted through contaminated food. Methods A systematic review was undertaken to identify reports on the risk factors for human cystic (CE) and alveolar (AE) echinococcosis. Data bases searched included PubMed, Scopus, Web of Knowledge, Cab Direct, Science Direct, Google Scholar, eLIBRARY.RU, CyberLeninka, CNKI and VIP. Search terms included Echinococc*, hydatid, epidemiology, logistic regression, risk factors, odds ratio, relative risk, risk factors. Reports, including grey literature where available, that had suitable data were selected and data were extracted. The main pathways of transmission were hypothesised to be contact with the definitive host, contaminated water, contaminated food and contaminated environment (other than food). For each study the attributable fraction for these potential sources of infection was calculated from the data presented. A meta-analysis was then undertaken to obtain pooled estimates for the relative contribution of these transmission pathways. Results Data from 28 cross-sectional studies and 14 case-control studies were extracted. There was strong evidence for transmission by direct contact with dogs for both CE and AE. The estimated attributable fractions were 26.1% (CI 13.8%-39.6%) and 34.4% (CI 20.7% -48.2%) respectively. Transmission through contaminated water was estimated to be responsible for approximately 29.4% (CI 12.1%-51.7%) for CE and 24.8% (CI 10.6% to 42.6%) for AE. Contaminated food may be responsible for approximately 23.4% of CE cases (CI 2.1%-47.3%). Globally, there was insufficient evidence to conclude AE can be transmitted by food, ... |
format |
Article in Journal/Newspaper |
author |
Paul R Torgerson Lucy J Robertson Heidi L Enemark Junwei Foehr Joke W B van der Giessen Christian M O Kapel Ivana Klun Chiara Trevisan |
author_facet |
Paul R Torgerson Lucy J Robertson Heidi L Enemark Junwei Foehr Joke W B van der Giessen Christian M O Kapel Ivana Klun Chiara Trevisan |
author_sort |
Paul R Torgerson |
title |
Source attribution of human echinococcosis: A systematic review and meta-analysis. |
title_short |
Source attribution of human echinococcosis: A systematic review and meta-analysis. |
title_full |
Source attribution of human echinococcosis: A systematic review and meta-analysis. |
title_fullStr |
Source attribution of human echinococcosis: A systematic review and meta-analysis. |
title_full_unstemmed |
Source attribution of human echinococcosis: A systematic review and meta-analysis. |
title_sort |
source attribution of human echinococcosis: a systematic review and meta-analysis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008382 https://doaj.org/article/59a4e4ba6ece440a9c8e5177cfc95baa |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008382 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008382 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008382 https://doaj.org/article/59a4e4ba6ece440a9c8e5177cfc95baa |
op_doi |
https://doi.org/10.1371/journal.pntd.0008382 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
14 |
container_issue |
6 |
container_start_page |
e0008382 |
_version_ |
1766346710095757312 |