Anti-inflammatory activities of arthropod peptides: a systematic review
Abstract Peptides obtained from different animal species have gained importance recently due to research that aims to develop biopharmaceuticals with therapeutic potential. In this sense, arthropod venoms have drawn attention, not only because of their toxicity but mainly for the search for molecule...
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ftdoajarticles:oai:doaj.org/article:589df01d44154639bbda50b7ae164273 2023-05-15T15:12:45+02:00 Anti-inflammatory activities of arthropod peptides: a systematic review Ariane Teixeira dos Santos Gabriela Silva Cruz Gandhi Rádis Baptista 2021-10-01T00:00:00Z https://doi.org/10.1590/1678-9199-jvatitd-2020-0152 https://doaj.org/article/589df01d44154639bbda50b7ae164273 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992021000100212&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1590/1678-9199-jvatitd-2020-0152 https://doaj.org/article/589df01d44154639bbda50b7ae164273 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021) Venom Peptides Anti-inflammatory Arthropods Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2021 ftdoajarticles https://doi.org/10.1590/1678-9199-jvatitd-2020-0152 2022-12-31T16:27:37Z Abstract Peptides obtained from different animal species have gained importance recently due to research that aims to develop biopharmaceuticals with therapeutic potential. In this sense, arthropod venoms have drawn attention, not only because of their toxicity but mainly for the search for molecules with various bioactivities, including anti-inflammatory activity. The purpose of the present study is to gather data available in the literature on new peptides derived from arthropod species with anti-inflammatory potential. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Studies on peptides from arthropods that display anti-inflammatory activity were retrieved from PubMed, Scopus, Web of Science, and Google Scholar databases. The bibliographic research started in 2020 and searched papers without a limit on the publication date. The articles were analyzed using a search string containing the following terms: “Peptides” and “Anti-inflammatory”, in combinations such as “Ant”, “Bee”, “Wasp”, “Crab”, “Shrimp”, “Scorpion”, “Spider”, “Tick” and “Centipedes”. Besides, a search was carried out in the databases with the terms: “Peptides”, “Antitumor”, or “Anticancer”, and “Arthropods”. Articles that met the inclusion and exclusion criteria totalized 171, and these served for data extraction. Additionally, the present review included anti-inflammatory peptides with anticancer properties. Peptides with confirmed anti-inflammatory activity were from insects (ants, bees, and wasps), crustaceans (shrimp and crabs), arachnids (scorpions, spiders, and ticks), and centipedes. These arthropod peptides act mainly by decreasing pro-inflammatory cytokines as analyzed in vitro and in vivo. Some showed significant antineoplastic activity, working in essential cellular pathways against malignant neoplasms. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Prisma ENVELOPE(-58.767,-58.767,-69.200,-69.200) Journal of Venomous Animals and Toxins including Tropical Diseases 27 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Venom Peptides Anti-inflammatory Arthropods Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Venom Peptides Anti-inflammatory Arthropods Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Ariane Teixeira dos Santos Gabriela Silva Cruz Gandhi Rádis Baptista Anti-inflammatory activities of arthropod peptides: a systematic review |
topic_facet |
Venom Peptides Anti-inflammatory Arthropods Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Abstract Peptides obtained from different animal species have gained importance recently due to research that aims to develop biopharmaceuticals with therapeutic potential. In this sense, arthropod venoms have drawn attention, not only because of their toxicity but mainly for the search for molecules with various bioactivities, including anti-inflammatory activity. The purpose of the present study is to gather data available in the literature on new peptides derived from arthropod species with anti-inflammatory potential. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Studies on peptides from arthropods that display anti-inflammatory activity were retrieved from PubMed, Scopus, Web of Science, and Google Scholar databases. The bibliographic research started in 2020 and searched papers without a limit on the publication date. The articles were analyzed using a search string containing the following terms: “Peptides” and “Anti-inflammatory”, in combinations such as “Ant”, “Bee”, “Wasp”, “Crab”, “Shrimp”, “Scorpion”, “Spider”, “Tick” and “Centipedes”. Besides, a search was carried out in the databases with the terms: “Peptides”, “Antitumor”, or “Anticancer”, and “Arthropods”. Articles that met the inclusion and exclusion criteria totalized 171, and these served for data extraction. Additionally, the present review included anti-inflammatory peptides with anticancer properties. Peptides with confirmed anti-inflammatory activity were from insects (ants, bees, and wasps), crustaceans (shrimp and crabs), arachnids (scorpions, spiders, and ticks), and centipedes. These arthropod peptides act mainly by decreasing pro-inflammatory cytokines as analyzed in vitro and in vivo. Some showed significant antineoplastic activity, working in essential cellular pathways against malignant neoplasms. |
format |
Article in Journal/Newspaper |
author |
Ariane Teixeira dos Santos Gabriela Silva Cruz Gandhi Rádis Baptista |
author_facet |
Ariane Teixeira dos Santos Gabriela Silva Cruz Gandhi Rádis Baptista |
author_sort |
Ariane Teixeira dos Santos |
title |
Anti-inflammatory activities of arthropod peptides: a systematic review |
title_short |
Anti-inflammatory activities of arthropod peptides: a systematic review |
title_full |
Anti-inflammatory activities of arthropod peptides: a systematic review |
title_fullStr |
Anti-inflammatory activities of arthropod peptides: a systematic review |
title_full_unstemmed |
Anti-inflammatory activities of arthropod peptides: a systematic review |
title_sort |
anti-inflammatory activities of arthropod peptides: a systematic review |
publisher |
SciELO |
publishDate |
2021 |
url |
https://doi.org/10.1590/1678-9199-jvatitd-2020-0152 https://doaj.org/article/589df01d44154639bbda50b7ae164273 |
long_lat |
ENVELOPE(-58.767,-58.767,-69.200,-69.200) |
geographic |
Arctic Prisma |
geographic_facet |
Arctic Prisma |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992021000100212&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1590/1678-9199-jvatitd-2020-0152 https://doaj.org/article/589df01d44154639bbda50b7ae164273 |
op_doi |
https://doi.org/10.1590/1678-9199-jvatitd-2020-0152 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
27 |
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