Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri
Harmful algae blooms have expanded greatly in recent decades, and their secreted toxins pose a severe threat to human health and marine ecosystems. Saxitoxin (STX) is a main paralytic shellfish poison naturally produced by marine microalgae of the genus Alexandrium. Despite numerous studies have ass...
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ftdoajarticles:oai:doaj.org/article:587fb1079a7145d89c4f773477a81e08 2023-05-15T15:57:42+02:00 Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri Ruiwen Cao Dan Wang Qianyu Wei Qing Wang Dinglong Yang Hui Liu Zhijun Dong Xiaoli Zhang Qianqian Zhang Jianmin Zhao 2018-08-01T00:00:00Z https://doi.org/10.3389/fphys.2018.01173 https://doaj.org/article/587fb1079a7145d89c4f773477a81e08 EN eng Frontiers Media S.A. https://www.frontiersin.org/article/10.3389/fphys.2018.01173/full https://doaj.org/toc/1664-042X 1664-042X doi:10.3389/fphys.2018.01173 https://doaj.org/article/587fb1079a7145d89c4f773477a81e08 Frontiers in Physiology, Vol 9 (2018) saxitoxin Crassostrea gigas Chlamys farreri oxidative stress immunotoxicity Physiology QP1-981 article 2018 ftdoajarticles https://doi.org/10.3389/fphys.2018.01173 2022-12-31T09:05:34Z Harmful algae blooms have expanded greatly in recent decades, and their secreted toxins pose a severe threat to human health and marine ecosystems. Saxitoxin (STX) is a main paralytic shellfish poison naturally produced by marine microalgae of the genus Alexandrium. Despite numerous studies have assessed the impacts of STX on marine bivalves, comparative in vivo study on the toxicity of STX on bivalves with distinct accumulation ability (such as oysters and scallops) has been seldom investigated. The aim of this study was to identify whether distinct sensitivity exists between oysters, Crassostrea gigas, and scallops, Chlamys farreri under the same amount of STX exposure using multiple biomarker responses. The responses of different biochemical markers including oxidative stress markers (catalase, superoxide dismutase, glutathione S-transferase, and lipid peroxidation) and immunotoxicity biomarkers (hemocyte phagocytosis rate, reactive oxidative species production, and DNA damages) were evaluated in bivalves after 12, 48, and 96 h of exposure to STX. The integrated biomarker responses value combined with two-way ANOVA analysis suggested that STX posed slightly severer stress on scallops than oysters for the extended period of time. This study provided preliminary results on the usefulness of a multi-biomarker approach to assess the toxicity associated with STX exposure in marine bivalves. Article in Journal/Newspaper Crassostrea gigas Directory of Open Access Journals: DOAJ Articles Frontiers in Physiology 9 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
saxitoxin Crassostrea gigas Chlamys farreri oxidative stress immunotoxicity Physiology QP1-981 |
spellingShingle |
saxitoxin Crassostrea gigas Chlamys farreri oxidative stress immunotoxicity Physiology QP1-981 Ruiwen Cao Dan Wang Qianyu Wei Qing Wang Dinglong Yang Hui Liu Zhijun Dong Xiaoli Zhang Qianqian Zhang Jianmin Zhao Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri |
topic_facet |
saxitoxin Crassostrea gigas Chlamys farreri oxidative stress immunotoxicity Physiology QP1-981 |
description |
Harmful algae blooms have expanded greatly in recent decades, and their secreted toxins pose a severe threat to human health and marine ecosystems. Saxitoxin (STX) is a main paralytic shellfish poison naturally produced by marine microalgae of the genus Alexandrium. Despite numerous studies have assessed the impacts of STX on marine bivalves, comparative in vivo study on the toxicity of STX on bivalves with distinct accumulation ability (such as oysters and scallops) has been seldom investigated. The aim of this study was to identify whether distinct sensitivity exists between oysters, Crassostrea gigas, and scallops, Chlamys farreri under the same amount of STX exposure using multiple biomarker responses. The responses of different biochemical markers including oxidative stress markers (catalase, superoxide dismutase, glutathione S-transferase, and lipid peroxidation) and immunotoxicity biomarkers (hemocyte phagocytosis rate, reactive oxidative species production, and DNA damages) were evaluated in bivalves after 12, 48, and 96 h of exposure to STX. The integrated biomarker responses value combined with two-way ANOVA analysis suggested that STX posed slightly severer stress on scallops than oysters for the extended period of time. This study provided preliminary results on the usefulness of a multi-biomarker approach to assess the toxicity associated with STX exposure in marine bivalves. |
format |
Article in Journal/Newspaper |
author |
Ruiwen Cao Dan Wang Qianyu Wei Qing Wang Dinglong Yang Hui Liu Zhijun Dong Xiaoli Zhang Qianqian Zhang Jianmin Zhao |
author_facet |
Ruiwen Cao Dan Wang Qianyu Wei Qing Wang Dinglong Yang Hui Liu Zhijun Dong Xiaoli Zhang Qianqian Zhang Jianmin Zhao |
author_sort |
Ruiwen Cao |
title |
Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri |
title_short |
Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri |
title_full |
Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri |
title_fullStr |
Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri |
title_full_unstemmed |
Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri |
title_sort |
integrative biomarker assessment of the influence of saxitoxin on marine bivalves: a comparative study of the two bivalve species oysters, crassostrea gigas, and scallops, chlamys farreri |
publisher |
Frontiers Media S.A. |
publishDate |
2018 |
url |
https://doi.org/10.3389/fphys.2018.01173 https://doaj.org/article/587fb1079a7145d89c4f773477a81e08 |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_source |
Frontiers in Physiology, Vol 9 (2018) |
op_relation |
https://www.frontiersin.org/article/10.3389/fphys.2018.01173/full https://doaj.org/toc/1664-042X 1664-042X doi:10.3389/fphys.2018.01173 https://doaj.org/article/587fb1079a7145d89c4f773477a81e08 |
op_doi |
https://doi.org/10.3389/fphys.2018.01173 |
container_title |
Frontiers in Physiology |
container_volume |
9 |
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1766393385493463040 |