Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015
Meningococcal meningitis is a public health concern in Africa. Conjugated vaccine against serogroup A Neisseria meningitidis (MenAfriVac) was used in mass vaccination and was proved to have a good impact in the meningitis belt. There is a lack of information about the impact of this intervention in...
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ftdoajarticles:oai:doaj.org/article:586d74e38475409b941d53a1b90e5ae4 2023-05-15T15:09:52+02:00 Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 Bouba Gake Bonaventure Babinne Graobe Bouba Abdouraman Crescence Satou Ngah Ahmadou Aissatou Nelly-Michèle Gake Elise Claudine Seukap Elias Nchiwan Nukenine Alain G. Etoundi Mballa Marie-Christine Fonkoua Jean-Pierre Lombart 2021-01-01T00:00:00Z https://doi.org/10.1155/2021/4314892 https://doaj.org/article/586d74e38475409b941d53a1b90e5ae4 EN eng Hindawi Limited http://dx.doi.org/10.1155/2021/4314892 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2021/4314892 https://doaj.org/article/586d74e38475409b941d53a1b90e5ae4 Journal of Tropical Medicine, Vol 2021 (2021) Arctic medicine. Tropical medicine RC955-962 article 2021 ftdoajarticles https://doi.org/10.1155/2021/4314892 2022-12-31T16:34:55Z Meningococcal meningitis is a public health concern in Africa. Conjugated vaccine against serogroup A Neisseria meningitidis (MenAfriVac) was used in mass vaccination and was proved to have a good impact in the meningitis belt. There is a lack of information about the impact of this intervention in Cameroon after mass vaccination was undertaken. This study aimed at filling the gap in its unknown impact in Cameroon. A retrospective longitudinal study using biological monitoring data of case-by-case-based surveillance for meningitis was obtained from the National Reference Laboratories from 1 January 2009 to 20 September 2015. Immunization coverage data were obtained from Regional Public Health Delegations where immunizations took place. We compared the risks of vaccine serogroup occurrence before and after vaccinations and calculated the global impact using Halloran’s formula. Annual cases of meningitis A decreased gradually from 92 in 2011 to 34 in 2012 and then to 1 case in 2013, and since 2014, no cases have been detected. The impact was estimated at 14.48% (p=0.41) in 2012 and then at 98.63% (p<0.0001) after the end of vaccinations in 2013. This survey confirms the effectiveness of the MenAfriVac vaccine in Cameroon as expected by the WHO. The surveillance must be pursued and enhanced to monitor coming immunizations measures with multivalent conjugated vaccines for this changing threat. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2021 1 8 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Bouba Gake Bonaventure Babinne Graobe Bouba Abdouraman Crescence Satou Ngah Ahmadou Aissatou Nelly-Michèle Gake Elise Claudine Seukap Elias Nchiwan Nukenine Alain G. Etoundi Mballa Marie-Christine Fonkoua Jean-Pierre Lombart Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Meningococcal meningitis is a public health concern in Africa. Conjugated vaccine against serogroup A Neisseria meningitidis (MenAfriVac) was used in mass vaccination and was proved to have a good impact in the meningitis belt. There is a lack of information about the impact of this intervention in Cameroon after mass vaccination was undertaken. This study aimed at filling the gap in its unknown impact in Cameroon. A retrospective longitudinal study using biological monitoring data of case-by-case-based surveillance for meningitis was obtained from the National Reference Laboratories from 1 January 2009 to 20 September 2015. Immunization coverage data were obtained from Regional Public Health Delegations where immunizations took place. We compared the risks of vaccine serogroup occurrence before and after vaccinations and calculated the global impact using Halloran’s formula. Annual cases of meningitis A decreased gradually from 92 in 2011 to 34 in 2012 and then to 1 case in 2013, and since 2014, no cases have been detected. The impact was estimated at 14.48% (p=0.41) in 2012 and then at 98.63% (p<0.0001) after the end of vaccinations in 2013. This survey confirms the effectiveness of the MenAfriVac vaccine in Cameroon as expected by the WHO. The surveillance must be pursued and enhanced to monitor coming immunizations measures with multivalent conjugated vaccines for this changing threat. |
format |
Article in Journal/Newspaper |
author |
Bouba Gake Bonaventure Babinne Graobe Bouba Abdouraman Crescence Satou Ngah Ahmadou Aissatou Nelly-Michèle Gake Elise Claudine Seukap Elias Nchiwan Nukenine Alain G. Etoundi Mballa Marie-Christine Fonkoua Jean-Pierre Lombart |
author_facet |
Bouba Gake Bonaventure Babinne Graobe Bouba Abdouraman Crescence Satou Ngah Ahmadou Aissatou Nelly-Michèle Gake Elise Claudine Seukap Elias Nchiwan Nukenine Alain G. Etoundi Mballa Marie-Christine Fonkoua Jean-Pierre Lombart |
author_sort |
Bouba Gake |
title |
Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 |
title_short |
Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 |
title_full |
Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 |
title_fullStr |
Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 |
title_full_unstemmed |
Impact of MenAfriVac on Meningococcal A Meningitis in Cameroon: A Retrospective Study Using Case-by-Case-Based Surveillance Data from 2009 to 2015 |
title_sort |
impact of menafrivac on meningococcal a meningitis in cameroon: a retrospective study using case-by-case-based surveillance data from 2009 to 2015 |
publisher |
Hindawi Limited |
publishDate |
2021 |
url |
https://doi.org/10.1155/2021/4314892 https://doaj.org/article/586d74e38475409b941d53a1b90e5ae4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2021 (2021) |
op_relation |
http://dx.doi.org/10.1155/2021/4314892 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2021/4314892 https://doaj.org/article/586d74e38475409b941d53a1b90e5ae4 |
op_doi |
https://doi.org/10.1155/2021/4314892 |
container_title |
Journal of Tropical Medicine |
container_volume |
2021 |
container_start_page |
1 |
op_container_end_page |
8 |
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1766340969892937728 |