Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis.
Background The novel coronavirus (COVID-19), caused by SARS-CoV-2, showed various prevalence and case-fatality rates (CFR) among patients with different pre-existing chronic conditions. End-stage renal disease (ESRD) patients with renal replacement therapy (RRT) might have a higher prevalence and CF...
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ftdoajarticles:oai:doaj.org/article:58375d84600b4854aed1276c34eac7ea 2023-05-15T15:12:48+02:00 Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. Tanawin Nopsopon Jathurong Kittrakulrat Kullaya Takkavatakarn Thanee Eiamsitrakoon Talerngsak Kanjanabuch Krit Pongpirul 2021-06-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0009156 https://doaj.org/article/58375d84600b4854aed1276c34eac7ea EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0009156 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009156 https://doaj.org/article/58375d84600b4854aed1276c34eac7ea PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009156 (2021) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles https://doi.org/10.1371/journal.pntd.0009156 2022-12-31T11:55:03Z Background The novel coronavirus (COVID-19), caused by SARS-CoV-2, showed various prevalence and case-fatality rates (CFR) among patients with different pre-existing chronic conditions. End-stage renal disease (ESRD) patients with renal replacement therapy (RRT) might have a higher prevalence and CFR due to reduced immune function from uremia and kidney tropism of SARS-CoV-2, but there was a lack of systematic study on the infection and mortality of the SARS-CoV-2 infection in ESRD patients with various RRT. Methodology/principal findings We searched five electronic databases and performed a systematic review and meta-analysis up to June 30, 2020, to evaluate the prevalence and case fatality rate (CFR) of the COVID-19 infection among ESRD patients with RRT. The global COVID-19 data were retrieved from the international database on June 30, 2020, for estimating the prevalence and CFR of the general population as referencing points. Of 3,272 potential studies, 34 were eligible studies consisted of 1,944 COVID-19 confirmed cases in 21,873 ESRD patients with RRT from 12 countries in four WHO regions. The overall pooled prevalence in ESRD patients with RRT was 3.10% [95% confidence interval (CI) 1.25-5.72] which was higher than referencing 0.14% global average prevalence. The overall estimated CFR of COVID-19 in ESRD patients with RRT was 18.06% (95% CI 14.09-22.32) which was higher than the global average at 4.98%. Conclusions This meta-analysis suggested high COVID-19 prevalence and CFR in ESRD patients with RRT. ESRD patients with RRT should have their specific protocol of COVID-19 prevention and treatment to mitigate excess cases and deaths. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 15 6 e0009156 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Tanawin Nopsopon Jathurong Kittrakulrat Kullaya Takkavatakarn Thanee Eiamsitrakoon Talerngsak Kanjanabuch Krit Pongpirul Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background The novel coronavirus (COVID-19), caused by SARS-CoV-2, showed various prevalence and case-fatality rates (CFR) among patients with different pre-existing chronic conditions. End-stage renal disease (ESRD) patients with renal replacement therapy (RRT) might have a higher prevalence and CFR due to reduced immune function from uremia and kidney tropism of SARS-CoV-2, but there was a lack of systematic study on the infection and mortality of the SARS-CoV-2 infection in ESRD patients with various RRT. Methodology/principal findings We searched five electronic databases and performed a systematic review and meta-analysis up to June 30, 2020, to evaluate the prevalence and case fatality rate (CFR) of the COVID-19 infection among ESRD patients with RRT. The global COVID-19 data were retrieved from the international database on June 30, 2020, for estimating the prevalence and CFR of the general population as referencing points. Of 3,272 potential studies, 34 were eligible studies consisted of 1,944 COVID-19 confirmed cases in 21,873 ESRD patients with RRT from 12 countries in four WHO regions. The overall pooled prevalence in ESRD patients with RRT was 3.10% [95% confidence interval (CI) 1.25-5.72] which was higher than referencing 0.14% global average prevalence. The overall estimated CFR of COVID-19 in ESRD patients with RRT was 18.06% (95% CI 14.09-22.32) which was higher than the global average at 4.98%. Conclusions This meta-analysis suggested high COVID-19 prevalence and CFR in ESRD patients with RRT. ESRD patients with RRT should have their specific protocol of COVID-19 prevention and treatment to mitigate excess cases and deaths. |
format |
Article in Journal/Newspaper |
author |
Tanawin Nopsopon Jathurong Kittrakulrat Kullaya Takkavatakarn Thanee Eiamsitrakoon Talerngsak Kanjanabuch Krit Pongpirul |
author_facet |
Tanawin Nopsopon Jathurong Kittrakulrat Kullaya Takkavatakarn Thanee Eiamsitrakoon Talerngsak Kanjanabuch Krit Pongpirul |
author_sort |
Tanawin Nopsopon |
title |
Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. |
title_short |
Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. |
title_full |
Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. |
title_fullStr |
Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. |
title_full_unstemmed |
Covid-19 in end-stage renal disease patients with renal replacement therapies: A systematic review and meta-analysis. |
title_sort |
covid-19 in end-stage renal disease patients with renal replacement therapies: a systematic review and meta-analysis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doi.org/10.1371/journal.pntd.0009156 https://doaj.org/article/58375d84600b4854aed1276c34eac7ea |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009156 (2021) |
op_relation |
https://doi.org/10.1371/journal.pntd.0009156 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009156 https://doaj.org/article/58375d84600b4854aed1276c34eac7ea |
op_doi |
https://doi.org/10.1371/journal.pntd.0009156 |
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PLOS Neglected Tropical Diseases |
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15 |
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e0009156 |
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