High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study.
Background Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, usi...
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ftdoajarticles:oai:doaj.org/article:57dbaa67e8af4f35a77215be54a07e87 2023-05-15T15:07:25+02:00 High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. Joan Gómez-Junyent David Paredes Juan Carlos Hurtado Ana Requena-Méndez Angel Ruiz Maria Eugenia Valls Jordi Vila Jose Muñoz 2018-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007010 https://doaj.org/article/57dbaa67e8af4f35a77215be54a07e87 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0007010 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007010 https://doaj.org/article/57dbaa67e8af4f35a77215be54a07e87 PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0007010 (2018) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007010 2022-12-31T07:36:44Z Background Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Methodology Retrospective study including all deceased potential donors from endemic areas of strongyloidiasis considered for SOT between January 2004 and December 2014 in a tertiary care hospital. The commercial serological test IVD-Elisa was used to determine the serological prevalence of S. stercoralis. Principal findings Among 1025 deceased individuals during the study period, 90 were from endemic areas of strongyloidiasis. There were available serum samples for 65 patients and 6 of them tested positive for S. stercoralis (9.23%). Only one of the deceased candidates was finally a donor, without transmitting the infection. Conclusions Among deceased individuals from endemic areas considered for SOT donation, seroprevalence of strongyloidiasis was high. This highlights the importance of adhering to current recommendations on screening for S. stercoralis among potential SOT donors at high risk of the infection, together with the need of developing a rapid diagnostic test to fully implement these screening strategies. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 12 11 e0007010 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Joan Gómez-Junyent David Paredes Juan Carlos Hurtado Ana Requena-Méndez Angel Ruiz Maria Eugenia Valls Jordi Vila Jose Muñoz High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Methodology Retrospective study including all deceased potential donors from endemic areas of strongyloidiasis considered for SOT between January 2004 and December 2014 in a tertiary care hospital. The commercial serological test IVD-Elisa was used to determine the serological prevalence of S. stercoralis. Principal findings Among 1025 deceased individuals during the study period, 90 were from endemic areas of strongyloidiasis. There were available serum samples for 65 patients and 6 of them tested positive for S. stercoralis (9.23%). Only one of the deceased candidates was finally a donor, without transmitting the infection. Conclusions Among deceased individuals from endemic areas considered for SOT donation, seroprevalence of strongyloidiasis was high. This highlights the importance of adhering to current recommendations on screening for S. stercoralis among potential SOT donors at high risk of the infection, together with the need of developing a rapid diagnostic test to fully implement these screening strategies. |
format |
Article in Journal/Newspaper |
author |
Joan Gómez-Junyent David Paredes Juan Carlos Hurtado Ana Requena-Méndez Angel Ruiz Maria Eugenia Valls Jordi Vila Jose Muñoz |
author_facet |
Joan Gómez-Junyent David Paredes Juan Carlos Hurtado Ana Requena-Méndez Angel Ruiz Maria Eugenia Valls Jordi Vila Jose Muñoz |
author_sort |
Joan Gómez-Junyent |
title |
High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. |
title_short |
High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. |
title_full |
High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. |
title_fullStr |
High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. |
title_full_unstemmed |
High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study. |
title_sort |
high seroprevalence of strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: a retrospective serum-bank based study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2018 |
url |
https://doi.org/10.1371/journal.pntd.0007010 https://doaj.org/article/57dbaa67e8af4f35a77215be54a07e87 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0007010 (2018) |
op_relation |
https://doi.org/10.1371/journal.pntd.0007010 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007010 https://doaj.org/article/57dbaa67e8af4f35a77215be54a07e87 |
op_doi |
https://doi.org/10.1371/journal.pntd.0007010 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
12 |
container_issue |
11 |
container_start_page |
e0007010 |
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