Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment
ABSTRACTINTRODUCTION:Cryptococcosis is an invasive disease acquired by inhalation of infectious propagules from the environment. Currently, compulsory notification of the spread of this disease is not required in Colombia. However, reporting of human immunodeficiency virus (HIV)/acquired immune defi...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
2015
|
Subjects: | |
Online Access: | https://doi.org/10.1590/0037-8682-0178-2015 https://doaj.org/article/57604dfe15c646e7bed231864d093620 |
id |
ftdoajarticles:oai:doaj.org/article:57604dfe15c646e7bed231864d093620 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:57604dfe15c646e7bed231864d093620 2023-05-15T15:12:06+02:00 Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment María Clara Noguera Patricia Escandón Elizabeth Castañeda 2015-10-01T00:00:00Z https://doi.org/10.1590/0037-8682-0178-2015 https://doaj.org/article/57604dfe15c646e7bed231864d093620 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000500580&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0178-2015 https://doaj.org/article/57604dfe15c646e7bed231864d093620 Revista da Sociedade Brasileira de Medicina Tropical, Vol 48, Iss 5, Pp 580-586 (2015) Cryptococcus neoformans Cryptococcus gattii Cryptococcosis Colombia Environment Arctic medicine. Tropical medicine RC955-962 article 2015 ftdoajarticles https://doi.org/10.1590/0037-8682-0178-2015 2022-12-31T02:52:31Z ABSTRACTINTRODUCTION:Cryptococcosis is an invasive disease acquired by inhalation of infectious propagules from the environment. Currently, compulsory notification of the spread of this disease is not required in Colombia. However, reporting of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome cases to the National Surveillance System has suggested that there is a growing population at risk of contracting cryptococcosis. Few studies have described the occurrence of cryptococcosis in Colombia. Therefore, in this study, we examined the pathology of this disease in Atlántico, Colombia and determined the distributions of Cryptococcus neoformans and Cryptococcus gattii in the environment.METHODS:Clinical samples/isolates were gathered from cases of cryptococcosis previously diagnosed at health institutions in Atlántico, and surveys were completed by clinicians. The environmental study considered 32 sampling points and three tree species, i.e., Quickstick ( Gliricidia sepium ), Almond ( Terminalia catappa ), and Pink trumpet ( Tabebuia rosea ). Environmental and clinical samples/isolates were analyzed for phenotypic and genotypic confirmation.RESULTS:From 1997-2014, 41 cases of cryptococcosis were reported. The mean patient age was 40.5 years (range: 18-63 years); 76% were men, and 78% were HIV positive. Isolation was possible in 38 cases ( C. neoformans , molecular type VNI in 37 cases and C. gattii , molecular type VGI in one case). In 2012-2014, 2,068 environmental samples were analyzed with a positivity of 0.4% ( C. neoformans , molecular type VNI) in Almond and Pink trumpet trees.CONCLUSIONS:Cryptococcus neoformans , molecular type VNI had a higher prevalence than C. gattii and was associated with human exposure and the pathogenesis of cryptococcosis in this geographical region. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Almond ENVELOPE(163.617,163.617,-78.383,-78.383) Arctic Revista da Sociedade Brasileira de Medicina Tropical 48 5 580 586 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Cryptococcus neoformans Cryptococcus gattii Cryptococcosis Colombia Environment Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Cryptococcus neoformans Cryptococcus gattii Cryptococcosis Colombia Environment Arctic medicine. Tropical medicine RC955-962 María Clara Noguera Patricia Escandón Elizabeth Castañeda Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
topic_facet |
Cryptococcus neoformans Cryptococcus gattii Cryptococcosis Colombia Environment Arctic medicine. Tropical medicine RC955-962 |
description |
ABSTRACTINTRODUCTION:Cryptococcosis is an invasive disease acquired by inhalation of infectious propagules from the environment. Currently, compulsory notification of the spread of this disease is not required in Colombia. However, reporting of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome cases to the National Surveillance System has suggested that there is a growing population at risk of contracting cryptococcosis. Few studies have described the occurrence of cryptococcosis in Colombia. Therefore, in this study, we examined the pathology of this disease in Atlántico, Colombia and determined the distributions of Cryptococcus neoformans and Cryptococcus gattii in the environment.METHODS:Clinical samples/isolates were gathered from cases of cryptococcosis previously diagnosed at health institutions in Atlántico, and surveys were completed by clinicians. The environmental study considered 32 sampling points and three tree species, i.e., Quickstick ( Gliricidia sepium ), Almond ( Terminalia catappa ), and Pink trumpet ( Tabebuia rosea ). Environmental and clinical samples/isolates were analyzed for phenotypic and genotypic confirmation.RESULTS:From 1997-2014, 41 cases of cryptococcosis were reported. The mean patient age was 40.5 years (range: 18-63 years); 76% were men, and 78% were HIV positive. Isolation was possible in 38 cases ( C. neoformans , molecular type VNI in 37 cases and C. gattii , molecular type VGI in one case). In 2012-2014, 2,068 environmental samples were analyzed with a positivity of 0.4% ( C. neoformans , molecular type VNI) in Almond and Pink trumpet trees.CONCLUSIONS:Cryptococcus neoformans , molecular type VNI had a higher prevalence than C. gattii and was associated with human exposure and the pathogenesis of cryptococcosis in this geographical region. |
format |
Article in Journal/Newspaper |
author |
María Clara Noguera Patricia Escandón Elizabeth Castañeda |
author_facet |
María Clara Noguera Patricia Escandón Elizabeth Castañeda |
author_sort |
María Clara Noguera |
title |
Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
title_short |
Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
title_full |
Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
title_fullStr |
Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
title_full_unstemmed |
Cryptococcosis in Atlántico, Colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
title_sort |
cryptococcosis in atlántico, colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2015 |
url |
https://doi.org/10.1590/0037-8682-0178-2015 https://doaj.org/article/57604dfe15c646e7bed231864d093620 |
long_lat |
ENVELOPE(163.617,163.617,-78.383,-78.383) |
geographic |
Almond Arctic |
geographic_facet |
Almond Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 48, Iss 5, Pp 580-586 (2015) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000500580&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0178-2015 https://doaj.org/article/57604dfe15c646e7bed231864d093620 |
op_doi |
https://doi.org/10.1590/0037-8682-0178-2015 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
48 |
container_issue |
5 |
container_start_page |
580 |
op_container_end_page |
586 |
_version_ |
1766342831660597248 |