Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review.
Mycetoma is a devastating, neglected tropical disease characterised by extensive tissue involvement resulting in destruction, deformities and disabilities in the affected patients. The hand is commonly affected by mycetoma thus compromises its functionality and hinder the patient's daily activi...
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ftdoajarticles:oai:doaj.org/article:5752275dee2a44609e845f1d7866d65e 2023-05-15T15:13:18+02:00 Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. Rowa Fathelrahman Omer Nancy Seif El Din Fadwa Awad Abdel Rahim Ahmed Hassan Fahal 2016-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004886 https://doaj.org/article/5752275dee2a44609e845f1d7866d65e EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4970814?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004886 https://doaj.org/article/5752275dee2a44609e845f1d7866d65e PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004886 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004886 2022-12-31T01:28:57Z Mycetoma is a devastating, neglected tropical disease characterised by extensive tissue involvement resulting in destruction, deformities and disabilities in the affected patients. The hand is commonly affected by mycetoma thus compromises its functionality and hinder the patient's daily activities of living. In this communication, we report on 533 patients with hand mycetoma managed over a period of 24 years at the Mycetoma Research Centre, University of Khartoum, Khartoum, Sudan. Eumycetoma was the commonest type of mycetoma (83.3%) encountered. Males were predominately affected (69.2%) with a sex ratio of 2.2:1. The majority of the patients (84%) were young adult below the age of 40 years old at presentation. The generality of patients (86.4%) were from the Sudan mycetoma belt. Children and adolescents (28.1%), farmers (18.2%) and workers (17.4%) were more frequently affected. The majority of patients (67.4%) had disease duration of less than 5 years at presentation. The study, did not document significant history of local trauma, familial tendency, concomitant medical diseases or other predisposing cause for mycetoma in this population. Pain (23.1%) was not a disease feature in this series and 52% of patients had past surgery for mycetoma and recurrence. The right hand was affected most (60.4%), and 64% of them had small lesion at presentation. Conventional x-ray was only helpful in patients with advanced disease and the MRI accurately determined the disease extension. Cytological smears, surgical biopsies histopathological examination and grains culture were the principal diagnostic tools for causative organisms' identification. In the present series it was difficult to determine the treatment outcome due to high patients follow up dropout. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 8 e0004886 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Rowa Fathelrahman Omer Nancy Seif El Din Fadwa Awad Abdel Rahim Ahmed Hassan Fahal Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Mycetoma is a devastating, neglected tropical disease characterised by extensive tissue involvement resulting in destruction, deformities and disabilities in the affected patients. The hand is commonly affected by mycetoma thus compromises its functionality and hinder the patient's daily activities of living. In this communication, we report on 533 patients with hand mycetoma managed over a period of 24 years at the Mycetoma Research Centre, University of Khartoum, Khartoum, Sudan. Eumycetoma was the commonest type of mycetoma (83.3%) encountered. Males were predominately affected (69.2%) with a sex ratio of 2.2:1. The majority of the patients (84%) were young adult below the age of 40 years old at presentation. The generality of patients (86.4%) were from the Sudan mycetoma belt. Children and adolescents (28.1%), farmers (18.2%) and workers (17.4%) were more frequently affected. The majority of patients (67.4%) had disease duration of less than 5 years at presentation. The study, did not document significant history of local trauma, familial tendency, concomitant medical diseases or other predisposing cause for mycetoma in this population. Pain (23.1%) was not a disease feature in this series and 52% of patients had past surgery for mycetoma and recurrence. The right hand was affected most (60.4%), and 64% of them had small lesion at presentation. Conventional x-ray was only helpful in patients with advanced disease and the MRI accurately determined the disease extension. Cytological smears, surgical biopsies histopathological examination and grains culture were the principal diagnostic tools for causative organisms' identification. In the present series it was difficult to determine the treatment outcome due to high patients follow up dropout. |
format |
Article in Journal/Newspaper |
author |
Rowa Fathelrahman Omer Nancy Seif El Din Fadwa Awad Abdel Rahim Ahmed Hassan Fahal |
author_facet |
Rowa Fathelrahman Omer Nancy Seif El Din Fadwa Awad Abdel Rahim Ahmed Hassan Fahal |
author_sort |
Rowa Fathelrahman Omer |
title |
Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. |
title_short |
Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. |
title_full |
Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. |
title_fullStr |
Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. |
title_full_unstemmed |
Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review. |
title_sort |
hand mycetoma: the mycetoma research centre experience and literature review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004886 https://doaj.org/article/5752275dee2a44609e845f1d7866d65e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004886 (2016) |
op_relation |
http://europepmc.org/articles/PMC4970814?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004886 https://doaj.org/article/5752275dee2a44609e845f1d7866d65e |
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https://doi.org/10.1371/journal.pntd.0004886 |
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PLOS Neglected Tropical Diseases |
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e0004886 |
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