Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome
A prospective study was carried out to determine if hyperferritinemia is a predictive factor for immunosuppression in patients with acquired immunodeficiency syndrome (AIDS). The population consisted of 40 patients hospitalized at the University Hospital of Maracaibo (Hospital Universitario de Marac...
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Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2011
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ftdoajarticles:oai:doaj.org/article:5734cbbc78d241ffac1ee271112459e8 2023-10-01T03:54:06+02:00 Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome Laura Palencia Rafael Villalobos Perozo 2011-02-01T00:00:00Z https://doaj.org/article/5734cbbc78d241ffac1ee271112459e8 EN ES eng spa Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales https://produccioncientificaluz.org/index.php/kasmera/article/view/4883 https://doaj.org/toc/0075-5222 https://doaj.org/toc/2477-9628 0075-5222 2477-9628 https://doaj.org/article/5734cbbc78d241ffac1ee271112459e8 Kasmera, Vol 39, Iss 2, Pp 130-139 (2011) sida hiperferritinemia factor pronóstico Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2011 ftdoajarticles 2023-09-03T00:43:37Z A prospective study was carried out to determine if hyperferritinemia is a predictive factor for immunosuppression in patients with acquired immunodeficiency syndrome (AIDS). The population consisted of 40 patients hospitalized at the University Hospital of Maracaibo (Hospital Universitario de Maracaibo), from January to October, 2010. Twenty-seven (67.50%) patients were male and 13 (32.50%) were female. 22.50% had a T CD4+ lymphocyte count between 200-400 cells/mm3 with a mean ferritin of 144.2 ± 127.1 ng/mL; 77.50% had a T CD4+ lymphocyte count of <200 cells/mm3 and a ferritin average of 1100.0 ± 984.7 ng/mL (p = 0.01). An inverse negative correlation was found between high ferritin levels and low T CD4+ lymphocyte count (r = 0.3135, p= 0.030), low numbers of leukocytes (r = 0, 7458 p = 0.012), low levels of protein (r = 0.5814, p =0.01), and a directly proportional relation with the increase of ESR (r = 0.7422, p = 0.001). In patients who died, the mean ferritin level (1180.0 ± 1,072) statistically (p = 0.018) was higher compared with the average ferritin level (474 ± 440.2) of patients who survived. Conclusions are that these results are sufficiently relevant to take hyperferritinemia into account as a prognostic factor for the immunosuppression of diagnosed AIDS patients. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Sida ENVELOPE(101.683,101.683,67.800,67.800) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish |
topic |
sida hiperferritinemia factor pronóstico Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
sida hiperferritinemia factor pronóstico Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Laura Palencia Rafael Villalobos Perozo Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome |
topic_facet |
sida hiperferritinemia factor pronóstico Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
A prospective study was carried out to determine if hyperferritinemia is a predictive factor for immunosuppression in patients with acquired immunodeficiency syndrome (AIDS). The population consisted of 40 patients hospitalized at the University Hospital of Maracaibo (Hospital Universitario de Maracaibo), from January to October, 2010. Twenty-seven (67.50%) patients were male and 13 (32.50%) were female. 22.50% had a T CD4+ lymphocyte count between 200-400 cells/mm3 with a mean ferritin of 144.2 ± 127.1 ng/mL; 77.50% had a T CD4+ lymphocyte count of <200 cells/mm3 and a ferritin average of 1100.0 ± 984.7 ng/mL (p = 0.01). An inverse negative correlation was found between high ferritin levels and low T CD4+ lymphocyte count (r = 0.3135, p= 0.030), low numbers of leukocytes (r = 0, 7458 p = 0.012), low levels of protein (r = 0.5814, p =0.01), and a directly proportional relation with the increase of ESR (r = 0.7422, p = 0.001). In patients who died, the mean ferritin level (1180.0 ± 1,072) statistically (p = 0.018) was higher compared with the average ferritin level (474 ± 440.2) of patients who survived. Conclusions are that these results are sufficiently relevant to take hyperferritinemia into account as a prognostic factor for the immunosuppression of diagnosed AIDS patients. |
format |
Article in Journal/Newspaper |
author |
Laura Palencia Rafael Villalobos Perozo |
author_facet |
Laura Palencia Rafael Villalobos Perozo |
author_sort |
Laura Palencia |
title |
Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome |
title_short |
Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome |
title_full |
Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome |
title_fullStr |
Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome |
title_full_unstemmed |
Hyperferritinemia as a Prognostic Factor for Immunosuppression in Patients with Acquired Immunodeficiency Syndrome |
title_sort |
hyperferritinemia as a prognostic factor for immunosuppression in patients with acquired immunodeficiency syndrome |
publisher |
Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales |
publishDate |
2011 |
url |
https://doaj.org/article/5734cbbc78d241ffac1ee271112459e8 |
long_lat |
ENVELOPE(101.683,101.683,67.800,67.800) |
geographic |
Arctic Sida |
geographic_facet |
Arctic Sida |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Kasmera, Vol 39, Iss 2, Pp 130-139 (2011) |
op_relation |
https://produccioncientificaluz.org/index.php/kasmera/article/view/4883 https://doaj.org/toc/0075-5222 https://doaj.org/toc/2477-9628 0075-5222 2477-9628 https://doaj.org/article/5734cbbc78d241ffac1ee271112459e8 |
_version_ |
1778521447807844352 |