Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study
Objective: To determine Toxoplasma gondii (T. gondii) as a cause of morbidity and mortality in human immunodeficiency virus (HIV) infected patients by ELISA method and to investigate toxoplasmosis-associated risk factors. Methods: This cross sectional study was conducted with 385 patients with HIV/A...
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ftdoajarticles:oai:doaj.org/article:5721d7bd523643ffb785c6a940a96219 2023-05-15T15:09:40+02:00 Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study Naser Nazari Arezoo Bozorgomid Alireza Janbakhsh Farshid Bashiri 2018-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.223562 https://doaj.org/article/5721d7bd523643ffb785c6a940a96219 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=1;spage=58;epage=62;aulast=Nazari https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.223562 https://doaj.org/article/5721d7bd523643ffb785c6a940a96219 Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 1, Pp 58-62 (2018) seroepidemiology toxoplasmosis hiv iran Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.4103/1995-7645.223562 2022-12-31T01:35:30Z Objective: To determine Toxoplasma gondii (T. gondii) as a cause of morbidity and mortality in human immunodeficiency virus (HIV) infected patients by ELISA method and to investigate toxoplasmosis-associated risk factors. Methods: This cross sectional study was conducted with 385 patients with HIV/AIDS referred to the behavior disease consultation center in Kermanshah, Iran between May 2012 and June 2013. Anti-Toxoplasma IgG and IgM antibodies were measured by using the ELISA method. Also, the relationship between the infection and age, gender, education, occupation, antiretroviral status, CD4+ cell counts and some other factors of the patients were assessed. P<0.05 was considered statistically significant. Results: Among the HIV-positive patients, 40.8% (157/358) and 2.6% (10/358) patients were positive for anti-T. gondii IgG and IgM antibodies, respectively. The mean CD4+ count in the patients with HIV was 327 cells/μL. A significant correlation was observed between the toxoplasmosis infections with the age group (P<0.05). Nevertheless, no statistically significant difference was found between gender, living area, educational level, occupational, marital status, antiretroviral status, prophylaxis, CD4+ cell count and toxoplasmosis. Conclusions: This study revealed that the patients with HIV infection were at the high risk of developing toxoplasmosis disease especially those patients who do not receive antiretroviral therapy and prophylaxis. The development and use of the effectiveness-based guidelines for controlling and the prevention reactivation of the latent T. gondii infection is required. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Medicine 11 1 58 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
seroepidemiology toxoplasmosis hiv iran Arctic medicine. Tropical medicine RC955-962 |
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seroepidemiology toxoplasmosis hiv iran Arctic medicine. Tropical medicine RC955-962 Naser Nazari Arezoo Bozorgomid Alireza Janbakhsh Farshid Bashiri Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study |
topic_facet |
seroepidemiology toxoplasmosis hiv iran Arctic medicine. Tropical medicine RC955-962 |
description |
Objective: To determine Toxoplasma gondii (T. gondii) as a cause of morbidity and mortality in human immunodeficiency virus (HIV) infected patients by ELISA method and to investigate toxoplasmosis-associated risk factors. Methods: This cross sectional study was conducted with 385 patients with HIV/AIDS referred to the behavior disease consultation center in Kermanshah, Iran between May 2012 and June 2013. Anti-Toxoplasma IgG and IgM antibodies were measured by using the ELISA method. Also, the relationship between the infection and age, gender, education, occupation, antiretroviral status, CD4+ cell counts and some other factors of the patients were assessed. P<0.05 was considered statistically significant. Results: Among the HIV-positive patients, 40.8% (157/358) and 2.6% (10/358) patients were positive for anti-T. gondii IgG and IgM antibodies, respectively. The mean CD4+ count in the patients with HIV was 327 cells/μL. A significant correlation was observed between the toxoplasmosis infections with the age group (P<0.05). Nevertheless, no statistically significant difference was found between gender, living area, educational level, occupational, marital status, antiretroviral status, prophylaxis, CD4+ cell count and toxoplasmosis. Conclusions: This study revealed that the patients with HIV infection were at the high risk of developing toxoplasmosis disease especially those patients who do not receive antiretroviral therapy and prophylaxis. The development and use of the effectiveness-based guidelines for controlling and the prevention reactivation of the latent T. gondii infection is required. |
format |
Article in Journal/Newspaper |
author |
Naser Nazari Arezoo Bozorgomid Alireza Janbakhsh Farshid Bashiri |
author_facet |
Naser Nazari Arezoo Bozorgomid Alireza Janbakhsh Farshid Bashiri |
author_sort |
Naser Nazari |
title |
Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study |
title_short |
Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study |
title_full |
Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study |
title_fullStr |
Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study |
title_full_unstemmed |
Toxoplasma gondii and human immunodeficiency virus co-infection in western Iran: A cross sectional study |
title_sort |
toxoplasma gondii and human immunodeficiency virus co-infection in western iran: a cross sectional study |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2018 |
url |
https://doi.org/10.4103/1995-7645.223562 https://doaj.org/article/5721d7bd523643ffb785c6a940a96219 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 1, Pp 58-62 (2018) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=1;spage=58;epage=62;aulast=Nazari https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.223562 https://doaj.org/article/5721d7bd523643ffb785c6a940a96219 |
op_doi |
https://doi.org/10.4103/1995-7645.223562 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
11 |
container_issue |
1 |
container_start_page |
58 |
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1766340816311156736 |