Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts
Abstract Background In this study, the efficacy of insecticide-treated nets was evaluated in terms of deterrence, blood-feeding inhibition, induced exophily and mortality on a wild resistant population of Anopheles epiroticus in southern Vietnam, in order to gain insight into the operational consequ...
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ftdoajarticles:oai:doaj.org/article:567d11a8fa774204862bbb8c5a5340be 2023-05-15T15:12:37+02:00 Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc 2009-10-01T00:00:00Z https://doi.org/10.1186/1475-2875-8-248 https://doaj.org/article/567d11a8fa774204862bbb8c5a5340be EN eng BMC http://www.malariajournal.com/content/8/1/248 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-8-248 1475-2875 https://doaj.org/article/567d11a8fa774204862bbb8c5a5340be Malaria Journal, Vol 8, Iss 1, p 248 (2009) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2009 ftdoajarticles https://doi.org/10.1186/1475-2875-8-248 2022-12-31T08:19:52Z Abstract Background In this study, the efficacy of insecticide-treated nets was evaluated in terms of deterrence, blood-feeding inhibition, induced exophily and mortality on a wild resistant population of Anopheles epiroticus in southern Vietnam, in order to gain insight into the operational consequences of the insecticide resistance observed in this malaria vector in the Mekong delta. Method An experimental station, based on the model of West Africa and adapted to the behaviour of the target species, was built in southern Vietnam. The study design was adapted from the WHO phase 2 guidelines. The study arms included a conventionally treated polyester net (CTN) with deltamethrin washed just before exhaustion, the WHO recommended long-lasting insecticidal net (LLIN) PermaNet 2.0 ® unwashed and 20 times washed and PermaNet 3.0 ® , designed for the control of pyrethroid resistant vectors, unwashed and 20 times washed. Results The nets still provided personal protection against the resistant An. epiroticus population. The personal protection ranged from 67% for deltamethrin CTN to 85% for unwashed PermaNet 3.0. Insecticide resistance in the An. epiroticus mosquitoes did not seem to alter the deterrent effect of pyrethroids. A significant higher mortality was still observed among the treatment arms despite the fact that the An. epiroticus population is resistant against the tested insecticides. Conclusion This study shows that CTN and LLINs still protect individuals against a pyrethroid resistant malaria vector from the Mekong region, where insecticide resistance is caused by a metabolic mechanism. In the light of a possible elimination of malaria from the Mekong region these insights in operational consequences of the insecticide resistance on control tools is of upmost importance. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 8 1 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background In this study, the efficacy of insecticide-treated nets was evaluated in terms of deterrence, blood-feeding inhibition, induced exophily and mortality on a wild resistant population of Anopheles epiroticus in southern Vietnam, in order to gain insight into the operational consequences of the insecticide resistance observed in this malaria vector in the Mekong delta. Method An experimental station, based on the model of West Africa and adapted to the behaviour of the target species, was built in southern Vietnam. The study design was adapted from the WHO phase 2 guidelines. The study arms included a conventionally treated polyester net (CTN) with deltamethrin washed just before exhaustion, the WHO recommended long-lasting insecticidal net (LLIN) PermaNet 2.0 ® unwashed and 20 times washed and PermaNet 3.0 ® , designed for the control of pyrethroid resistant vectors, unwashed and 20 times washed. Results The nets still provided personal protection against the resistant An. epiroticus population. The personal protection ranged from 67% for deltamethrin CTN to 85% for unwashed PermaNet 3.0. Insecticide resistance in the An. epiroticus mosquitoes did not seem to alter the deterrent effect of pyrethroids. A significant higher mortality was still observed among the treatment arms despite the fact that the An. epiroticus population is resistant against the tested insecticides. Conclusion This study shows that CTN and LLINs still protect individuals against a pyrethroid resistant malaria vector from the Mekong region, where insecticide resistance is caused by a metabolic mechanism. In the light of a possible elimination of malaria from the Mekong region these insights in operational consequences of the insecticide resistance on control tools is of upmost importance. |
format |
Article in Journal/Newspaper |
author |
Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc |
author_facet |
Trung Ho Speybroeck Niko Berkvens Dirk Chinh Vu Van Bortel Wim Coosemans Marc |
author_sort |
Trung Ho |
title |
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts |
title_short |
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts |
title_full |
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts |
title_fullStr |
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts |
title_full_unstemmed |
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts |
title_sort |
impact of insecticide-treated nets on wild pyrethroid resistant anopheles epiroticus population from southern vietnam tested in experimental huts |
publisher |
BMC |
publishDate |
2009 |
url |
https://doi.org/10.1186/1475-2875-8-248 https://doaj.org/article/567d11a8fa774204862bbb8c5a5340be |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 8, Iss 1, p 248 (2009) |
op_relation |
http://www.malariajournal.com/content/8/1/248 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-8-248 1475-2875 https://doaj.org/article/567d11a8fa774204862bbb8c5a5340be |
op_doi |
https://doi.org/10.1186/1475-2875-8-248 |
container_title |
Malaria Journal |
container_volume |
8 |
container_issue |
1 |
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1766343281995677696 |