Screening and antibacterial efficacy of selected Indian medicinal plants
Objective: To evaluate the antibacterial efficacy of five Indian medicinal plants such as Acalypha indica L. (A. indica), Aerva lanata (L.) Juss. ex Schult. (A. lanata), Clerodendrum inerme (L.) Gaertn., Pergularia daemia (Forsk.) Chiov. and Solanum surattense Burm. f. against opportunistic bacteria...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
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ftdoajarticles:oai:doaj.org/article:55c10996400240f5932821dbba450dd2 2023-05-15T15:13:47+02:00 Screening and antibacterial efficacy of selected Indian medicinal plants Suresh Mickymaray Mohammad Saleh Al Aboody Pradipta Kumar Rath Panneerselvam Annamalai Thajuddin Nooruddin 2016-03-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2015.12.005 https://doaj.org/article/55c10996400240f5932821dbba450dd2 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115308649 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2015.12.005 https://doaj.org/article/55c10996400240f5932821dbba450dd2 Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 3, Pp 185-191 (2016) Antibacterial efficacy Medicinal plants Bacterial pathogens Phytoconstituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2016 ftdoajarticles https://doi.org/10.1016/j.apjtb.2015.12.005 2022-12-31T00:52:12Z Objective: To evaluate the antibacterial efficacy of five Indian medicinal plants such as Acalypha indica L. (A. indica), Aerva lanata (L.) Juss. ex Schult. (A. lanata), Clerodendrum inerme (L.) Gaertn., Pergularia daemia (Forsk.) Chiov. and Solanum surattense Burm. f. against opportunistic bacterial pathogens isolated from HIV infected patients for the potential phytoconstituents in plant extracts. Methods: The opportunistic bacterial pathogens such as Escherichia coli (E. coli), Pseudomonas aeruginosa, Salmonella typhi and Serratia marcescens from Gram-negative group and Staphylococcus aureus from Gram-positive group were isolated from HIV infected patients. The antibacterial efficacy of ethanolic extracts of selected medicinal plants was carried out by disc diffusion method. The potential phytoconstituents of medicinal plant extracts were identified by gas chromatography and mass spectrometry (GC–MS) analysis. Results: Among the five medicinal plants tested, A. indica and A. lanata showed the significant antibacterial activity. A. indica showed potential activity against Staphylococcus aureus and E. coli. A. lanata significantly exhibited antibacterial activity against E. coli, Salmonella typhi and Pseudomonas aeruginosa. A total of 19 phytoconstituents were identified in the ethanolic extract of A. indica and A. lanata by GC–MS analysis respectively. Conclusions: The results of the present investigation revealed that A. indica and A. lanata, possessed significant antibacterial activity when compared with the other plant extracts tested. The presence of 3-O-methyl-d-glucose by GC–MS analysis in both A. indica and A. lanata extracts has not been reported elsewhere in the literature and the findings in this study could be the first one to report. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Indian Asian Pacific Journal of Tropical Biomedicine 6 3 185 191 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Antibacterial efficacy Medicinal plants Bacterial pathogens Phytoconstituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Antibacterial efficacy Medicinal plants Bacterial pathogens Phytoconstituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Suresh Mickymaray Mohammad Saleh Al Aboody Pradipta Kumar Rath Panneerselvam Annamalai Thajuddin Nooruddin Screening and antibacterial efficacy of selected Indian medicinal plants |
topic_facet |
Antibacterial efficacy Medicinal plants Bacterial pathogens Phytoconstituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the antibacterial efficacy of five Indian medicinal plants such as Acalypha indica L. (A. indica), Aerva lanata (L.) Juss. ex Schult. (A. lanata), Clerodendrum inerme (L.) Gaertn., Pergularia daemia (Forsk.) Chiov. and Solanum surattense Burm. f. against opportunistic bacterial pathogens isolated from HIV infected patients for the potential phytoconstituents in plant extracts. Methods: The opportunistic bacterial pathogens such as Escherichia coli (E. coli), Pseudomonas aeruginosa, Salmonella typhi and Serratia marcescens from Gram-negative group and Staphylococcus aureus from Gram-positive group were isolated from HIV infected patients. The antibacterial efficacy of ethanolic extracts of selected medicinal plants was carried out by disc diffusion method. The potential phytoconstituents of medicinal plant extracts were identified by gas chromatography and mass spectrometry (GC–MS) analysis. Results: Among the five medicinal plants tested, A. indica and A. lanata showed the significant antibacterial activity. A. indica showed potential activity against Staphylococcus aureus and E. coli. A. lanata significantly exhibited antibacterial activity against E. coli, Salmonella typhi and Pseudomonas aeruginosa. A total of 19 phytoconstituents were identified in the ethanolic extract of A. indica and A. lanata by GC–MS analysis respectively. Conclusions: The results of the present investigation revealed that A. indica and A. lanata, possessed significant antibacterial activity when compared with the other plant extracts tested. The presence of 3-O-methyl-d-glucose by GC–MS analysis in both A. indica and A. lanata extracts has not been reported elsewhere in the literature and the findings in this study could be the first one to report. |
format |
Article in Journal/Newspaper |
author |
Suresh Mickymaray Mohammad Saleh Al Aboody Pradipta Kumar Rath Panneerselvam Annamalai Thajuddin Nooruddin |
author_facet |
Suresh Mickymaray Mohammad Saleh Al Aboody Pradipta Kumar Rath Panneerselvam Annamalai Thajuddin Nooruddin |
author_sort |
Suresh Mickymaray |
title |
Screening and antibacterial efficacy of selected Indian medicinal plants |
title_short |
Screening and antibacterial efficacy of selected Indian medicinal plants |
title_full |
Screening and antibacterial efficacy of selected Indian medicinal plants |
title_fullStr |
Screening and antibacterial efficacy of selected Indian medicinal plants |
title_full_unstemmed |
Screening and antibacterial efficacy of selected Indian medicinal plants |
title_sort |
screening and antibacterial efficacy of selected indian medicinal plants |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2016 |
url |
https://doi.org/10.1016/j.apjtb.2015.12.005 https://doaj.org/article/55c10996400240f5932821dbba450dd2 |
geographic |
Arctic Indian |
geographic_facet |
Arctic Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 3, Pp 185-191 (2016) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115308649 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2015.12.005 https://doaj.org/article/55c10996400240f5932821dbba450dd2 |
op_doi |
https://doi.org/10.1016/j.apjtb.2015.12.005 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
6 |
container_issue |
3 |
container_start_page |
185 |
op_container_end_page |
191 |
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1766344311961550848 |