Health-related quality of life in patients with Chagas disease
INTRODUCTION: Chagas disease (ChD) is a chronic illness related to significant morbidity and mortality that can affect the quality of life (QoL) of infected patients. However, there are few studies regarding QoL in ChD. The objectives of this study are to construct a health-related QoL (HRQoL) profi...
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ftdoajarticles:oai:doaj.org/article:55397f16c0604a979b33698ae45ce7d9 2023-05-15T15:10:34+02:00 Health-related quality of life in patients with Chagas disease Bruna Guimarães Oliveira Mery Natali Silva Abreu Claudia Drummond Guimarães Abreu Manoel Otavio da Costa Rocha Antonio Luiz Ribeiro 2011-04-01T00:00:00Z https://doi.org/10.1590/s0037-86822011005000002 https://doaj.org/article/55397f16c0604a979b33698ae45ce7d9 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000200005&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/s0037-86822011005000002 https://doaj.org/article/55397f16c0604a979b33698ae45ce7d9 Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 2, Pp 150-156 (2011) Qualidade de vida Doença de Chagas SF-36 Minnesota Living with Heart Failure Questionnaire Arctic medicine. Tropical medicine RC955-962 article 2011 ftdoajarticles https://doi.org/10.1590/s0037-86822011005000002 2022-12-31T03:00:17Z INTRODUCTION: Chagas disease (ChD) is a chronic illness related to significant morbidity and mortality that can affect the quality of life (QoL) of infected patients. However, there are few studies regarding QoL in ChD. The objectives of this study are to construct a health-related QoL (HRQoL) profile of ChD patients and compare this with a non-ChD (NChD) group to identify factors associated with the worst HRQoL scores in ChD patients. METHODS: HRQoL was investigated in 125 patients with ChD and 21 NChD individuals using the Medical Outcomes Study 36-item Short-Form (SF-36) and the Minnesota Living with Heart Failure Questionnaire (MLWHFQ). Patients were submitted to a standard protocol that included clinical examination, ECG, Holter monitoring, Doppler echocardiogram and autonomic function tests. RESULTS: HRQoL scores were significantly worse among the ChD group compared to the NChD group in the SF-36 domains of physical functioning and role-emotional and in the MLWHFQ scale. For the ChD group, univariate analysis showed that HRQoL score quartiles were associated with level of education, sex, marital status, use of medication, functional classification and cardiovascular and gastrointestinal symptoms. In the multivariate analysis, female sex, fewer years of education, single status, worst functional classification, presence of cardiovascular and gastrointestinal symptoms, associated illnesses, Doppler echocardiographic abnormalities and ventricular arrhythmia detected during Holter monitoring were predictors of lower HRQoL scores. CONCLUSIONS: ChD patients showed worse HRQoL scores compared to NChD. For the ChD group, sociodemographic and clinical variables were associated with worst scores. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 44 2 150 156 |
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op_collection_id |
ftdoajarticles |
language |
English |
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Qualidade de vida Doença de Chagas SF-36 Minnesota Living with Heart Failure Questionnaire Arctic medicine. Tropical medicine RC955-962 |
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Qualidade de vida Doença de Chagas SF-36 Minnesota Living with Heart Failure Questionnaire Arctic medicine. Tropical medicine RC955-962 Bruna Guimarães Oliveira Mery Natali Silva Abreu Claudia Drummond Guimarães Abreu Manoel Otavio da Costa Rocha Antonio Luiz Ribeiro Health-related quality of life in patients with Chagas disease |
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Qualidade de vida Doença de Chagas SF-36 Minnesota Living with Heart Failure Questionnaire Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Chagas disease (ChD) is a chronic illness related to significant morbidity and mortality that can affect the quality of life (QoL) of infected patients. However, there are few studies regarding QoL in ChD. The objectives of this study are to construct a health-related QoL (HRQoL) profile of ChD patients and compare this with a non-ChD (NChD) group to identify factors associated with the worst HRQoL scores in ChD patients. METHODS: HRQoL was investigated in 125 patients with ChD and 21 NChD individuals using the Medical Outcomes Study 36-item Short-Form (SF-36) and the Minnesota Living with Heart Failure Questionnaire (MLWHFQ). Patients were submitted to a standard protocol that included clinical examination, ECG, Holter monitoring, Doppler echocardiogram and autonomic function tests. RESULTS: HRQoL scores were significantly worse among the ChD group compared to the NChD group in the SF-36 domains of physical functioning and role-emotional and in the MLWHFQ scale. For the ChD group, univariate analysis showed that HRQoL score quartiles were associated with level of education, sex, marital status, use of medication, functional classification and cardiovascular and gastrointestinal symptoms. In the multivariate analysis, female sex, fewer years of education, single status, worst functional classification, presence of cardiovascular and gastrointestinal symptoms, associated illnesses, Doppler echocardiographic abnormalities and ventricular arrhythmia detected during Holter monitoring were predictors of lower HRQoL scores. CONCLUSIONS: ChD patients showed worse HRQoL scores compared to NChD. For the ChD group, sociodemographic and clinical variables were associated with worst scores. |
format |
Article in Journal/Newspaper |
author |
Bruna Guimarães Oliveira Mery Natali Silva Abreu Claudia Drummond Guimarães Abreu Manoel Otavio da Costa Rocha Antonio Luiz Ribeiro |
author_facet |
Bruna Guimarães Oliveira Mery Natali Silva Abreu Claudia Drummond Guimarães Abreu Manoel Otavio da Costa Rocha Antonio Luiz Ribeiro |
author_sort |
Bruna Guimarães Oliveira |
title |
Health-related quality of life in patients with Chagas disease |
title_short |
Health-related quality of life in patients with Chagas disease |
title_full |
Health-related quality of life in patients with Chagas disease |
title_fullStr |
Health-related quality of life in patients with Chagas disease |
title_full_unstemmed |
Health-related quality of life in patients with Chagas disease |
title_sort |
health-related quality of life in patients with chagas disease |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2011 |
url |
https://doi.org/10.1590/s0037-86822011005000002 https://doaj.org/article/55397f16c0604a979b33698ae45ce7d9 |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 2, Pp 150-156 (2011) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000200005&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/s0037-86822011005000002 https://doaj.org/article/55397f16c0604a979b33698ae45ce7d9 |
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https://doi.org/10.1590/s0037-86822011005000002 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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44 |
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150 |
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156 |
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