INTRODUCTION: Sequential antibiotic therapy (SAT) is safe and economical. However, the unnecessary use of intravenous (IV) administration usually occurs. The objective of this work was to get to know the effectiveness of an intervention to implement the SAT in a teaching hospital in Brazil. METHODS:...
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ftdoajarticles:oai:doaj.org/article:547c783c157843d3a6db3e700350b3d2 2023-05-15T15:09:55+02:00 Raquel Melo Rodrigues Astrídia Marília de Souza Fontes Orlando César Mantese Renata Souza Martins Miguel Tanús Jorge 2013-01-01T00:00:00Z https://doaj.org/article/547c783c157843d3a6db3e700350b3d2 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100050 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/547c783c157843d3a6db3e700350b3d2 Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 1, Pp 50-54 (2013) Antibiotics Antimicrobial Antibiotic policy Switch therapy Arctic medicine. Tropical medicine RC955-962 article 2013 ftdoajarticles 2022-12-30T21:38:31Z INTRODUCTION: Sequential antibiotic therapy (SAT) is safe and economical. However, the unnecessary use of intravenous (IV) administration usually occurs. The objective of this work was to get to know the effectiveness of an intervention to implement the SAT in a teaching hospital in Brazil. METHODS: This was a prospective and interventional study, historically controlled, and was conducted in the Hospital de Clínicas, Universidade Federal de Uberlândia, State of Minas Gerais, Brazil, a high complexity teaching hospital having 503 beds. In each of the periods, from 04/04/05 to 07/20/05 (pre-intervention) and from 09/24/07 to 12/20/07 (intervention), 117 patients were evaluated. After the pre-intervention period, guidelines were developed which were implemented during the intervention period along with educational measures and a reminder system added to the patients' prescription. RESULTS: In the pre-intervention and intervention periods, the IV antibiotics were used as treatment for a average time of 14.8 and 11.8 days, respectively. Ceftriaxone was the antibiotic most prescribed in both periods (23.4% and 21.6% respectively). Starting from the first prescription of antibiotics, the average length of hospitalization time was 21.8 and 17.5 days, respectively. The SAT occurred only in 4 and 5 courses of treatment, respectively, and 12.8% and 18.8% of the patients died in the respective periods. CONCLUSIONS: Under the presented conditions, the evaluated intervention strategy is ineffective in promoting the exchange of the antibiotic administration from IV to oral treatment (SAT). Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Antibiotics Antimicrobial Antibiotic policy Switch therapy Arctic medicine. Tropical medicine RC955-962 |
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Antibiotics Antimicrobial Antibiotic policy Switch therapy Arctic medicine. Tropical medicine RC955-962 Raquel Melo Rodrigues Astrídia Marília de Souza Fontes Orlando César Mantese Renata Souza Martins Miguel Tanús Jorge |
topic_facet |
Antibiotics Antimicrobial Antibiotic policy Switch therapy Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Sequential antibiotic therapy (SAT) is safe and economical. However, the unnecessary use of intravenous (IV) administration usually occurs. The objective of this work was to get to know the effectiveness of an intervention to implement the SAT in a teaching hospital in Brazil. METHODS: This was a prospective and interventional study, historically controlled, and was conducted in the Hospital de Clínicas, Universidade Federal de Uberlândia, State of Minas Gerais, Brazil, a high complexity teaching hospital having 503 beds. In each of the periods, from 04/04/05 to 07/20/05 (pre-intervention) and from 09/24/07 to 12/20/07 (intervention), 117 patients were evaluated. After the pre-intervention period, guidelines were developed which were implemented during the intervention period along with educational measures and a reminder system added to the patients' prescription. RESULTS: In the pre-intervention and intervention periods, the IV antibiotics were used as treatment for a average time of 14.8 and 11.8 days, respectively. Ceftriaxone was the antibiotic most prescribed in both periods (23.4% and 21.6% respectively). Starting from the first prescription of antibiotics, the average length of hospitalization time was 21.8 and 17.5 days, respectively. The SAT occurred only in 4 and 5 courses of treatment, respectively, and 12.8% and 18.8% of the patients died in the respective periods. CONCLUSIONS: Under the presented conditions, the evaluated intervention strategy is ineffective in promoting the exchange of the antibiotic administration from IV to oral treatment (SAT). |
format |
Article in Journal/Newspaper |
author |
Raquel Melo Rodrigues Astrídia Marília de Souza Fontes Orlando César Mantese Renata Souza Martins Miguel Tanús Jorge |
author_facet |
Raquel Melo Rodrigues Astrídia Marília de Souza Fontes Orlando César Mantese Renata Souza Martins Miguel Tanús Jorge |
author_sort |
Raquel Melo Rodrigues |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2013 |
url |
https://doaj.org/article/547c783c157843d3a6db3e700350b3d2 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 1, Pp 50-54 (2013) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100050 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/547c783c157843d3a6db3e700350b3d2 |
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1766341016860753920 |