Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo-β-lactamase detection on multidrug-resistant Acinetobacter baumannii

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Letícia Eichstaedt Mayer, Rosmari Hörner, Maisa Kräulich Tizotti, Rosiéli Martini, Magda Cristina Souza Marques Roehrs, Cláudia Barbisan Kempfer
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2012
• Subjects: Resistência a medicamentos; Acinetobacter baumannii; Testes de sensibilidade microbiana; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/S0037-86822012000200021; https://doaj.org/article/5406babf98074e8ba6eed67c76fca97d

INTRODUCTION: Metallo-β-lactamase (MBL) has been reported all over the world. METHODS: The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concentration (MIC) for multidrug-resistant Acinetobacter baumanni strains. RESULTS: MPA significantly inhibited growth of the strains. CONCLUSIONS: The use of MPA can affect the results in phenotypic methods of MBL detection.