The disease burden of Taenia solium cysticercosis in Cameroon.
Background Taenia solium cysticercosis is an important zoonosis in many developing countries. Human neurocysticercosis is recognised as an important cause of epilepsy in regions where the parasite occurs. However, it is largely underreported and there is a lack of data about the disease burden. Beca...
Published in: | PLoS Neglected Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:5330ae17a82c4e6b9e1e6bc026d54a9b 2023-05-15T15:15:44+02:00 The disease burden of Taenia solium cysticercosis in Cameroon. Nicolas Praet Niko Speybroeck Rafael Manzanedo Dirk Berkvens Denis Nsame Nforninwe André Zoli Fabrice Quet Pierre-Marie Preux Hélène Carabin Stanny Geerts 2009-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0000406 https://doaj.org/article/5330ae17a82c4e6b9e1e6bc026d54a9b EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19333365/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000406 https://doaj.org/article/5330ae17a82c4e6b9e1e6bc026d54a9b PLoS Neglected Tropical Diseases, Vol 3, Iss 3, p e406 (2009) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2009 ftdoajarticles https://doi.org/10.1371/journal.pntd.0000406 2022-12-31T07:44:21Z Background Taenia solium cysticercosis is an important zoonosis in many developing countries. Human neurocysticercosis is recognised as an important cause of epilepsy in regions where the parasite occurs. However, it is largely underreported and there is a lack of data about the disease burden. Because a body of information on human and porcine cysticercosis in Cameroon is becoming available, the present study was undertaken to calculate the impact of this neglected zoonosis. Methods Both the cost and Disability Adjusted Life Year (DALY) estimations were applied. All necessary parameters were collected and imported in R software. Different distributions were used according to the type of information available for each of the parameters. Findings Based on a prevalence of epilepsy of 3.6%, the number of people with neurocysticercosis-associated epilepsy was estimated at 50,326 (95% CR 37,299-65,924), representing 1.0% of the local population, whereas the number of pigs diagnosed with cysticercosis was estimated at 15,961 (95% CR 12,320-20,044), which corresponds to 5.6% of the local pig population. The total annual costs due to T. solium cysticercosis in West Cameroon were estimated at 10,255,202 Euro (95% CR 6,889,048-14,754,044), of which 4.7% were due to losses in pig husbandry and 95.3% to direct and indirect losses caused by human cysticercosis. The monetary burden per case of cysticercosis amounts to 194 Euro (95% CR 147-253). The average number of DALYs lost was 9.0 per thousand persons per year (95% CR 2.8-20.4). Interpretation This study provides an estimation of the costs due to T. solium cysticercosis using country-specific parameters and including the human as well as the animal burden of the zoonotic disease. A comparison with a study in South Africa indicates that the cost of inactivity, influenced by salaries, plays a predominant role in the monetary burden of T. solium cysticercosis. Therefore, knowing the salary levels and the prevalence of the disease might allow a rapid indication of the total ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Daly ENVELOPE(63.761,63.761,-67.513,-67.513) PLoS Neglected Tropical Diseases 3 3 e406 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Nicolas Praet Niko Speybroeck Rafael Manzanedo Dirk Berkvens Denis Nsame Nforninwe André Zoli Fabrice Quet Pierre-Marie Preux Hélène Carabin Stanny Geerts The disease burden of Taenia solium cysticercosis in Cameroon. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Taenia solium cysticercosis is an important zoonosis in many developing countries. Human neurocysticercosis is recognised as an important cause of epilepsy in regions where the parasite occurs. However, it is largely underreported and there is a lack of data about the disease burden. Because a body of information on human and porcine cysticercosis in Cameroon is becoming available, the present study was undertaken to calculate the impact of this neglected zoonosis. Methods Both the cost and Disability Adjusted Life Year (DALY) estimations were applied. All necessary parameters were collected and imported in R software. Different distributions were used according to the type of information available for each of the parameters. Findings Based on a prevalence of epilepsy of 3.6%, the number of people with neurocysticercosis-associated epilepsy was estimated at 50,326 (95% CR 37,299-65,924), representing 1.0% of the local population, whereas the number of pigs diagnosed with cysticercosis was estimated at 15,961 (95% CR 12,320-20,044), which corresponds to 5.6% of the local pig population. The total annual costs due to T. solium cysticercosis in West Cameroon were estimated at 10,255,202 Euro (95% CR 6,889,048-14,754,044), of which 4.7% were due to losses in pig husbandry and 95.3% to direct and indirect losses caused by human cysticercosis. The monetary burden per case of cysticercosis amounts to 194 Euro (95% CR 147-253). The average number of DALYs lost was 9.0 per thousand persons per year (95% CR 2.8-20.4). Interpretation This study provides an estimation of the costs due to T. solium cysticercosis using country-specific parameters and including the human as well as the animal burden of the zoonotic disease. A comparison with a study in South Africa indicates that the cost of inactivity, influenced by salaries, plays a predominant role in the monetary burden of T. solium cysticercosis. Therefore, knowing the salary levels and the prevalence of the disease might allow a rapid indication of the total ... |
format |
Article in Journal/Newspaper |
author |
Nicolas Praet Niko Speybroeck Rafael Manzanedo Dirk Berkvens Denis Nsame Nforninwe André Zoli Fabrice Quet Pierre-Marie Preux Hélène Carabin Stanny Geerts |
author_facet |
Nicolas Praet Niko Speybroeck Rafael Manzanedo Dirk Berkvens Denis Nsame Nforninwe André Zoli Fabrice Quet Pierre-Marie Preux Hélène Carabin Stanny Geerts |
author_sort |
Nicolas Praet |
title |
The disease burden of Taenia solium cysticercosis in Cameroon. |
title_short |
The disease burden of Taenia solium cysticercosis in Cameroon. |
title_full |
The disease burden of Taenia solium cysticercosis in Cameroon. |
title_fullStr |
The disease burden of Taenia solium cysticercosis in Cameroon. |
title_full_unstemmed |
The disease burden of Taenia solium cysticercosis in Cameroon. |
title_sort |
disease burden of taenia solium cysticercosis in cameroon. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2009 |
url |
https://doi.org/10.1371/journal.pntd.0000406 https://doaj.org/article/5330ae17a82c4e6b9e1e6bc026d54a9b |
long_lat |
ENVELOPE(63.761,63.761,-67.513,-67.513) |
geographic |
Arctic Daly |
geographic_facet |
Arctic Daly |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 3, Iss 3, p e406 (2009) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19333365/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000406 https://doaj.org/article/5330ae17a82c4e6b9e1e6bc026d54a9b |
op_doi |
https://doi.org/10.1371/journal.pntd.0000406 |
container_title |
PLoS Neglected Tropical Diseases |
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3 |
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3 |
container_start_page |
e406 |
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1766346072618172416 |