Evolution of the recombination regulator PRDM9 in minke whales

• Published in: BMC Genomics
• Main Authors: Elena Damm, Kristian K. Ullrich, William B. Amos, Linda Odenthal-Hesse
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2022
• Subjects: PRDM9; Minke whales; Balaenoptera acutorostrata; Balaenoptera bonaerensis; Microsatellite loci; mtDNA; Biotechnology; TP248.13-248.65; Genetics; QH426-470; Antarctic; The Antarctic; Pacific; Krab; Antarc*; Antarctic Minke whale; minke whale; North Atlantic
• Online Access: https://doi.org/10.1186/s12864-022-08305-1; https://doaj.org/article/524804e8e99f431f904ed760f6bd6f10

Abstract Background PRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the PRDM9 protein recognizes and binds specific target motifs via its array of C2H2 zinc-fingers encoded by a rapidly evolving minisatellite. The gen...