Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia
Objective: To investigate the prevalence and risk factors of brucellosis in human and animal’s communities in southern Saudi Arabia. Methods: A cross-sectional sero-epidemiological study was conducted in Aseer and Jazan, Saudi Arabia (October 2017-October 2018). Human serum samples (n=339) were init...
Published in: | Asian Pacific Journal of Tropical Medicine |
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Wolters Kluwer Medknow Publications
2019
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Online Access: | https://doi.org/10.4103/1995-7645.272484 https://doaj.org/article/52219af7121a4c1a9633f348f191c439 |
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ftdoajarticles:oai:doaj.org/article:52219af7121a4c1a9633f348f191c439 2023-05-15T15:16:08+02:00 Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia Ahmed M. Al-Hakami Abdulah J. Alqahtani Riyad A. Moosa Sultan K. Kadasah Talal Y. Gofashe Amer F. Binzafrah Abdulrahman M. Almobty Ihab Abdulrahim Abdullah M. Alkahtani Shehata F. Shehata Mohamed E. Hamid 2019-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.272484 https://doaj.org/article/52219af7121a4c1a9633f348f191c439 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2019;volume=12;issue=12;spage=545;epage=551;aulast=Al-Hakami https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.272484 https://doaj.org/article/52219af7121a4c1a9633f348f191c439 Asian Pacific Journal of Tropical Medicine, Vol 12, Iss 12, Pp 545-551 (2019) undulant fever zoonosis serological assays brucellosis aseer Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.4103/1995-7645.272484 2022-12-31T14:20:33Z Objective: To investigate the prevalence and risk factors of brucellosis in human and animal’s communities in southern Saudi Arabia. Methods: A cross-sectional sero-epidemiological study was conducted in Aseer and Jazan, Saudi Arabia (October 2017-October 2018). Human serum samples (n=339) were initially screened for Brucella antibodies and positive samples were further titrated for Brucella antibodies by immunocapture assay (titer of ⩾1:320 as positive). Animal samples (n=828) were screened using the Rose Bengal test. Relationship status was dichotomized to measure and predict independent contributions to variations in human using univariate and multivariate stepwise binary logistic regression model. Results: The rate of brucellosis among the 339 human samples in the two regions was 33.9%, and the rate of acute brucellosis was 12.4%. The rate of brucellosis in animals was 4.7%. Human brucellosis among the target groups was higher in northwestern Aseer (53.3%) compared to Southeastern Aseer (25.9%) and Jazan region (20.6%). The disease was more prevalent among non-Saudi nationals (35.2%) compared to Saudis (30.5%). The rate of brucellosis among butchers and shepherds was 37.5% and 37.2%, respectively. The rate of brucellosis was 37.8% in people over 30 years of age. Our univariate analysis showed that residing in Aseer region (OR: 2.60, 95% CI: 1.50-4.40), especially residing in northwestern Aseer region (OR: 4.40, 95% CI: 2.40-7.90), frequent consumption of raw meat (OR: 2.90, 95% CI: 1.50-5.50), shepherds (OR: 2.10, 95% CI: 0.80-5.30), owning sheep (OR: 2.20, 95% CI: 1.10-4.40), daily contact with animals (OR: 2.10, 95% CI: 0.75-5.80), and those > 30-year-old (OR: 1.50, 95% CI: 1.00-2.40) were significantly associated with increased risks of brucellosis. Our multivariate analysis further showed that residing in northwestern Aseer (OR: 9.16, 95% CI: 3.39-24.76) and having sheep (OR: 1.16, 95% CI: 1.00-1.35) were significant and independent risks of brucellosis while residing in agricultural region (OR: 0.28, ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Medicine 12 12 545 |
institution |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
undulant fever zoonosis serological assays brucellosis aseer Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
undulant fever zoonosis serological assays brucellosis aseer Arctic medicine. Tropical medicine RC955-962 Ahmed M. Al-Hakami Abdulah J. Alqahtani Riyad A. Moosa Sultan K. Kadasah Talal Y. Gofashe Amer F. Binzafrah Abdulrahman M. Almobty Ihab Abdulrahim Abdullah M. Alkahtani Shehata F. Shehata Mohamed E. Hamid Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia |
topic_facet |
undulant fever zoonosis serological assays brucellosis aseer Arctic medicine. Tropical medicine RC955-962 |
description |
Objective: To investigate the prevalence and risk factors of brucellosis in human and animal’s communities in southern Saudi Arabia. Methods: A cross-sectional sero-epidemiological study was conducted in Aseer and Jazan, Saudi Arabia (October 2017-October 2018). Human serum samples (n=339) were initially screened for Brucella antibodies and positive samples were further titrated for Brucella antibodies by immunocapture assay (titer of ⩾1:320 as positive). Animal samples (n=828) were screened using the Rose Bengal test. Relationship status was dichotomized to measure and predict independent contributions to variations in human using univariate and multivariate stepwise binary logistic regression model. Results: The rate of brucellosis among the 339 human samples in the two regions was 33.9%, and the rate of acute brucellosis was 12.4%. The rate of brucellosis in animals was 4.7%. Human brucellosis among the target groups was higher in northwestern Aseer (53.3%) compared to Southeastern Aseer (25.9%) and Jazan region (20.6%). The disease was more prevalent among non-Saudi nationals (35.2%) compared to Saudis (30.5%). The rate of brucellosis among butchers and shepherds was 37.5% and 37.2%, respectively. The rate of brucellosis was 37.8% in people over 30 years of age. Our univariate analysis showed that residing in Aseer region (OR: 2.60, 95% CI: 1.50-4.40), especially residing in northwestern Aseer region (OR: 4.40, 95% CI: 2.40-7.90), frequent consumption of raw meat (OR: 2.90, 95% CI: 1.50-5.50), shepherds (OR: 2.10, 95% CI: 0.80-5.30), owning sheep (OR: 2.20, 95% CI: 1.10-4.40), daily contact with animals (OR: 2.10, 95% CI: 0.75-5.80), and those > 30-year-old (OR: 1.50, 95% CI: 1.00-2.40) were significantly associated with increased risks of brucellosis. Our multivariate analysis further showed that residing in northwestern Aseer (OR: 9.16, 95% CI: 3.39-24.76) and having sheep (OR: 1.16, 95% CI: 1.00-1.35) were significant and independent risks of brucellosis while residing in agricultural region (OR: 0.28, ... |
format |
Article in Journal/Newspaper |
author |
Ahmed M. Al-Hakami Abdulah J. Alqahtani Riyad A. Moosa Sultan K. Kadasah Talal Y. Gofashe Amer F. Binzafrah Abdulrahman M. Almobty Ihab Abdulrahim Abdullah M. Alkahtani Shehata F. Shehata Mohamed E. Hamid |
author_facet |
Ahmed M. Al-Hakami Abdulah J. Alqahtani Riyad A. Moosa Sultan K. Kadasah Talal Y. Gofashe Amer F. Binzafrah Abdulrahman M. Almobty Ihab Abdulrahim Abdullah M. Alkahtani Shehata F. Shehata Mohamed E. Hamid |
author_sort |
Ahmed M. Al-Hakami |
title |
Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia |
title_short |
Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia |
title_full |
Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia |
title_fullStr |
Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia |
title_full_unstemmed |
Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia |
title_sort |
seroprevalence of brucellosis among exposed agro-pastoral communities in southern saudi arabia |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2019 |
url |
https://doi.org/10.4103/1995-7645.272484 https://doaj.org/article/52219af7121a4c1a9633f348f191c439 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 12, Iss 12, Pp 545-551 (2019) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2019;volume=12;issue=12;spage=545;epage=551;aulast=Al-Hakami https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.272484 https://doaj.org/article/52219af7121a4c1a9633f348f191c439 |
op_doi |
https://doi.org/10.4103/1995-7645.272484 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
12 |
container_issue |
12 |
container_start_page |
545 |
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1766346430775033856 |