Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas
Abstract: Cutaneous leishmaniosis of the New World (CLNW) is a health problem in rural areas of Venezuela. Patients with muco-cutaneous ulcers tend to present intercurrent infections of the lesions by pyogenic bacteria. After removing skin specimens from the ulcer borders for microscopic demonstrati...
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Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2009
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ftdoajarticles:oai:doaj.org/article:51d6a68237e54feebfe6bfbc7eee908e 2023-10-09T21:49:34+02:00 Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas Navarro Pedro Silva, Sylvia De la Parte María A Colmenares Luis Alfonso Coraspe Virginia Garrido Elinor Redondo, María C 2009-12-01T00:00:00Z https://doaj.org/article/51d6a68237e54feebfe6bfbc7eee908e EN ES eng spa Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales https://drive.google.com/file/d/12Lndf5snJwcWWUnwyHiImcL88U776LgE/view https://doaj.org/toc/0075-5222 https://doaj.org/toc/2477-9628 0075-5222 2477-9628 https://doaj.org/article/51d6a68237e54feebfe6bfbc7eee908e Kasmera, Vol 37, Iss 2, Pp 131-139 (2009) Leishmaniosis leishmaniosis tegumentaria americana enfermedades infecciosas parasitarias antimoniales pentavalentes medicina tropical tegumentary leishmaniosis of the New World parasitic infectious diseases tropical medicine Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2009 ftdoajarticles 2023-09-10T00:49:28Z Abstract: Cutaneous leishmaniosis of the New World (CLNW) is a health problem in rural areas of Venezuela. Patients with muco-cutaneous ulcers tend to present intercurrent infections of the lesions by pyogenic bacteria. After removing skin specimens from the ulcer borders for microscopic demonstration of Leishmania spp amastigotes, forty-one patients with the disease, being treated with cefadroxil per os were studied. Most of the patients came from rural Miranda state, were male adults and had one ulcer on a lower limb. Confirmatory diagnosis was made using the Montenegro test, or Leishmanin immunoserology (IFAT) and demonstration of the presence of parasites in the skin samples. All the patients were positive for the Leishmanin test, while parasites were observed in 51% of the skin smears colored by the Giemsa procedure. After a week of treatment with cefadroxil, bacterial infections were reduced and a decrease in bacterial load was also noted when visualizing the parasite from the skin smears. Patients were treated with intramuscular antimony meglumine for 10-day periods with an intervening rest period. All patients responded adequately to the meglumine antileishmania treatment; the lesions healed and accompanying tributary lymph nodes disappeared. Conclusion: Cefadroxil is a suitable antibiotic for treating intercurrent pyogenic infections in cases of tegumentary leishmaniosis. Since leishmaniosis is considered an emerging disease, a search for appropriate, alternative therapies is required. Resumen: La leishmaniosis tegumentaria americana es un problema de salud en el medio rural venezolano. Las úlceras leishmánicas tienden a infectarse secundariamente por bacterias piógenas. Se evaluaron 41 pacientes con la enfermedad que recibieron cefadroxilo oral previo a la toma de segmentos de piel del borde de las úlceras para la demostración microscópica de Leishmania spp. La mayoría de los pacientes eran adultos masculinos y provenían del medio rural del estado Miranda, con una úlcera única localizada en los ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish |
topic |
Leishmaniosis leishmaniosis tegumentaria americana enfermedades infecciosas parasitarias antimoniales pentavalentes medicina tropical tegumentary leishmaniosis of the New World parasitic infectious diseases tropical medicine Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Leishmaniosis leishmaniosis tegumentaria americana enfermedades infecciosas parasitarias antimoniales pentavalentes medicina tropical tegumentary leishmaniosis of the New World parasitic infectious diseases tropical medicine Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Navarro Pedro Silva, Sylvia De la Parte María A Colmenares Luis Alfonso Coraspe Virginia Garrido Elinor Redondo, María C Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
topic_facet |
Leishmaniosis leishmaniosis tegumentaria americana enfermedades infecciosas parasitarias antimoniales pentavalentes medicina tropical tegumentary leishmaniosis of the New World parasitic infectious diseases tropical medicine Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Abstract: Cutaneous leishmaniosis of the New World (CLNW) is a health problem in rural areas of Venezuela. Patients with muco-cutaneous ulcers tend to present intercurrent infections of the lesions by pyogenic bacteria. After removing skin specimens from the ulcer borders for microscopic demonstration of Leishmania spp amastigotes, forty-one patients with the disease, being treated with cefadroxil per os were studied. Most of the patients came from rural Miranda state, were male adults and had one ulcer on a lower limb. Confirmatory diagnosis was made using the Montenegro test, or Leishmanin immunoserology (IFAT) and demonstration of the presence of parasites in the skin samples. All the patients were positive for the Leishmanin test, while parasites were observed in 51% of the skin smears colored by the Giemsa procedure. After a week of treatment with cefadroxil, bacterial infections were reduced and a decrease in bacterial load was also noted when visualizing the parasite from the skin smears. Patients were treated with intramuscular antimony meglumine for 10-day periods with an intervening rest period. All patients responded adequately to the meglumine antileishmania treatment; the lesions healed and accompanying tributary lymph nodes disappeared. Conclusion: Cefadroxil is a suitable antibiotic for treating intercurrent pyogenic infections in cases of tegumentary leishmaniosis. Since leishmaniosis is considered an emerging disease, a search for appropriate, alternative therapies is required. Resumen: La leishmaniosis tegumentaria americana es un problema de salud en el medio rural venezolano. Las úlceras leishmánicas tienden a infectarse secundariamente por bacterias piógenas. Se evaluaron 41 pacientes con la enfermedad que recibieron cefadroxilo oral previo a la toma de segmentos de piel del borde de las úlceras para la demostración microscópica de Leishmania spp. La mayoría de los pacientes eran adultos masculinos y provenían del medio rural del estado Miranda, con una úlcera única localizada en los ... |
format |
Article in Journal/Newspaper |
author |
Navarro Pedro Silva, Sylvia De la Parte María A Colmenares Luis Alfonso Coraspe Virginia Garrido Elinor Redondo, María C |
author_facet |
Navarro Pedro Silva, Sylvia De la Parte María A Colmenares Luis Alfonso Coraspe Virginia Garrido Elinor Redondo, María C |
author_sort |
Navarro Pedro |
title |
Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
title_short |
Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
title_full |
Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
title_fullStr |
Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
title_full_unstemmed |
Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
title_sort |
utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas |
publisher |
Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales |
publishDate |
2009 |
url |
https://doaj.org/article/51d6a68237e54feebfe6bfbc7eee908e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Kasmera, Vol 37, Iss 2, Pp 131-139 (2009) |
op_relation |
https://drive.google.com/file/d/12Lndf5snJwcWWUnwyHiImcL88U776LgE/view https://doaj.org/toc/0075-5222 https://doaj.org/toc/2477-9628 0075-5222 2477-9628 https://doaj.org/article/51d6a68237e54feebfe6bfbc7eee908e |
_version_ |
1779312588062982144 |