Serological evidence of louse-borne relapsing fever in northern Kenya
Background: Tick- and louse-borne relapsing fever are highly-neglected, vector-borne diseases caused by diverse Borrelia species. Presently, there are no data available on the endemicity of tick- and louse-borne relapsing fever spirochetes in Kenya. Here, we present data of a retrospective study on...
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ftdoajarticles:oai:doaj.org/article:50e08e04b396485ea0f4e38eedd1ec06 2024-09-09T19:25:53+00:00 Serological evidence of louse-borne relapsing fever in northern Kenya Flavia Reyer Martyna Olesiuk Florian Röttgerding Volker Fingerle Abdulrahman Adamu Dan Waithiru John Njeru Peter Kraiczy 2024-05-01T00:00:00Z https://doi.org/10.1016/j.tmaid.2024.102714 https://doaj.org/article/50e08e04b396485ea0f4e38eedd1ec06 EN eng Elsevier http://www.sciencedirect.com/science/article/pii/S1477893924000280 https://doaj.org/toc/1873-0442 1873-0442 doi:10.1016/j.tmaid.2024.102714 https://doaj.org/article/50e08e04b396485ea0f4e38eedd1ec06 Travel Medicine and Infectious Disease, Vol 59, Iss , Pp 102714- (2024) Neglected infectious disease Vector-borne zoonosis Epidemiology Spirochetes Borrelia Borrelia recurrentis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2024 ftdoajarticles https://doi.org/10.1016/j.tmaid.2024.102714 2024-08-05T17:49:25Z Background: Tick- and louse-borne relapsing fever are highly-neglected, vector-borne diseases caused by diverse Borrelia species. Presently, there are no data available on the endemicity of tick- and louse-borne relapsing fever spirochetes in Kenya. Here, we present data of a retrospective study on the seroprevalence of louse-borne relapsing fever (LBRF) in northern Kenya. Methods: A novel immunoassay, recently established for the diagnosis of LBRF was utilized to screen 2005 blood samples collected from individuals with fever without a source in Turkana County, Kenya between May 2009 and November 2010 for anti-LBRF antibodies. Results: Out of the 2005 sera analyzed, 287 samples (14.3 %) were considered anti-LBRF IgG positive. Subsequent analyses revealed that 87 out of 152 sera randomly selected from these 2005 samples were tested positive (57.2 %) for anti-LBRF IgM antibodies. Most of the IgG and IgM positive samples were from individuals living in northern regions of Turkana County. Conclusion: Our serological finding provides strong evidence for the occurrence of LBRF in Kenya. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Travel Medicine and Infectious Disease 59 102714 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Neglected infectious disease Vector-borne zoonosis Epidemiology Spirochetes Borrelia Borrelia recurrentis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Neglected infectious disease Vector-borne zoonosis Epidemiology Spirochetes Borrelia Borrelia recurrentis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Flavia Reyer Martyna Olesiuk Florian Röttgerding Volker Fingerle Abdulrahman Adamu Dan Waithiru John Njeru Peter Kraiczy Serological evidence of louse-borne relapsing fever in northern Kenya |
topic_facet |
Neglected infectious disease Vector-borne zoonosis Epidemiology Spirochetes Borrelia Borrelia recurrentis Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Background: Tick- and louse-borne relapsing fever are highly-neglected, vector-borne diseases caused by diverse Borrelia species. Presently, there are no data available on the endemicity of tick- and louse-borne relapsing fever spirochetes in Kenya. Here, we present data of a retrospective study on the seroprevalence of louse-borne relapsing fever (LBRF) in northern Kenya. Methods: A novel immunoassay, recently established for the diagnosis of LBRF was utilized to screen 2005 blood samples collected from individuals with fever without a source in Turkana County, Kenya between May 2009 and November 2010 for anti-LBRF antibodies. Results: Out of the 2005 sera analyzed, 287 samples (14.3 %) were considered anti-LBRF IgG positive. Subsequent analyses revealed that 87 out of 152 sera randomly selected from these 2005 samples were tested positive (57.2 %) for anti-LBRF IgM antibodies. Most of the IgG and IgM positive samples were from individuals living in northern regions of Turkana County. Conclusion: Our serological finding provides strong evidence for the occurrence of LBRF in Kenya. |
format |
Article in Journal/Newspaper |
author |
Flavia Reyer Martyna Olesiuk Florian Röttgerding Volker Fingerle Abdulrahman Adamu Dan Waithiru John Njeru Peter Kraiczy |
author_facet |
Flavia Reyer Martyna Olesiuk Florian Röttgerding Volker Fingerle Abdulrahman Adamu Dan Waithiru John Njeru Peter Kraiczy |
author_sort |
Flavia Reyer |
title |
Serological evidence of louse-borne relapsing fever in northern Kenya |
title_short |
Serological evidence of louse-borne relapsing fever in northern Kenya |
title_full |
Serological evidence of louse-borne relapsing fever in northern Kenya |
title_fullStr |
Serological evidence of louse-borne relapsing fever in northern Kenya |
title_full_unstemmed |
Serological evidence of louse-borne relapsing fever in northern Kenya |
title_sort |
serological evidence of louse-borne relapsing fever in northern kenya |
publisher |
Elsevier |
publishDate |
2024 |
url |
https://doi.org/10.1016/j.tmaid.2024.102714 https://doaj.org/article/50e08e04b396485ea0f4e38eedd1ec06 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Travel Medicine and Infectious Disease, Vol 59, Iss , Pp 102714- (2024) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S1477893924000280 https://doaj.org/toc/1873-0442 1873-0442 doi:10.1016/j.tmaid.2024.102714 https://doaj.org/article/50e08e04b396485ea0f4e38eedd1ec06 |
op_doi |
https://doi.org/10.1016/j.tmaid.2024.102714 |
container_title |
Travel Medicine and Infectious Disease |
container_volume |
59 |
container_start_page |
102714 |
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1809895594697687040 |