Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes
The presence of serological markers for hepatitis B virus (HBsAg, anti-HBc IgM and Anti-HBc total) was investigated in the serum of 1,396 individuals who had clinical suspect of hepatitis. It was observed that 50.7% of the individuals were positive and, from the total of the studied individuals, 14....
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Universidade de São Paulo (USP)
2002
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ftdoajarticles:oai:doaj.org/article:50d9c28e0e4f4424b6530a4f598f0ba6 2024-09-09T19:25:31+00:00 Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes Claudia de Oliveira e SILVA Marli da Silva Pereira AZEVEDO Célia Maria de Almeida SOARES Regina Maria Bringel MARTINS Carmen Helena RAMOS Roberto Ruhman DAHER Divina das Dôres de Paula CARDOSO 2002-12-01T00:00:00Z https://doaj.org/article/50d9c28e0e4f4424b6530a4f598f0ba6 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652002000600007&tlng=en https://doaj.org/toc/1678-9946 1678-9946 https://doaj.org/article/50d9c28e0e4f4424b6530a4f598f0ba6 Revista do Instituto de Medicina Tropical de São Paulo, Vol 44, Iss 6, Pp 331-334 (2002) Hepatitis B HBV-DNA Subtypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2002 ftdoajarticles 2024-08-05T17:49:30Z The presence of serological markers for hepatitis B virus (HBsAg, anti-HBc IgM and Anti-HBc total) was investigated in the serum of 1,396 individuals who had clinical suspect of hepatitis. It was observed that 50.7% of the individuals were positive and, from the total of the studied individuals, 14.5% were positive for HBsAg. From these, 8.5% were also positive for anti-HBc IgM. The analysis in relation to gender showed a higher seroprevalence index among male individuals (p < 0.0001). It was observed the occurrence of subtypes adw2 (62.7%), ayw3 (23.5%), ayw2 (9.8%) and adw4 (3.9%). The viral DNA was detected in 61 (33.9%) HBsAg positive samples and in one sample positive only for anti-HBc total. These results indicate an important incidence of the HBV infection in this population, and reinforce previous studies regarding this virus in the central west region of Brazil. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Hepatitis B HBV-DNA Subtypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Hepatitis B HBV-DNA Subtypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Claudia de Oliveira e SILVA Marli da Silva Pereira AZEVEDO Célia Maria de Almeida SOARES Regina Maria Bringel MARTINS Carmen Helena RAMOS Roberto Ruhman DAHER Divina das Dôres de Paula CARDOSO Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes |
topic_facet |
Hepatitis B HBV-DNA Subtypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
The presence of serological markers for hepatitis B virus (HBsAg, anti-HBc IgM and Anti-HBc total) was investigated in the serum of 1,396 individuals who had clinical suspect of hepatitis. It was observed that 50.7% of the individuals were positive and, from the total of the studied individuals, 14.5% were positive for HBsAg. From these, 8.5% were also positive for anti-HBc IgM. The analysis in relation to gender showed a higher seroprevalence index among male individuals (p < 0.0001). It was observed the occurrence of subtypes adw2 (62.7%), ayw3 (23.5%), ayw2 (9.8%) and adw4 (3.9%). The viral DNA was detected in 61 (33.9%) HBsAg positive samples and in one sample positive only for anti-HBc total. These results indicate an important incidence of the HBV infection in this population, and reinforce previous studies regarding this virus in the central west region of Brazil. |
format |
Article in Journal/Newspaper |
author |
Claudia de Oliveira e SILVA Marli da Silva Pereira AZEVEDO Célia Maria de Almeida SOARES Regina Maria Bringel MARTINS Carmen Helena RAMOS Roberto Ruhman DAHER Divina das Dôres de Paula CARDOSO |
author_facet |
Claudia de Oliveira e SILVA Marli da Silva Pereira AZEVEDO Célia Maria de Almeida SOARES Regina Maria Bringel MARTINS Carmen Helena RAMOS Roberto Ruhman DAHER Divina das Dôres de Paula CARDOSO |
author_sort |
Claudia de Oliveira e SILVA |
title |
Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes |
title_short |
Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes |
title_full |
Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes |
title_fullStr |
Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes |
title_full_unstemmed |
Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes |
title_sort |
seroprevalence of hepatitis b virus infection in individuals with clinical evidence of hepatitis in goiânia, goiás: detection of viral dna and determination of subtypes |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2002 |
url |
https://doaj.org/article/50d9c28e0e4f4424b6530a4f598f0ba6 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 44, Iss 6, Pp 331-334 (2002) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652002000600007&tlng=en https://doaj.org/toc/1678-9946 1678-9946 https://doaj.org/article/50d9c28e0e4f4424b6530a4f598f0ba6 |
_version_ |
1809895291728429056 |