Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst

The simultaneous use of a biocatalyst (lipase Candida antarctica) and a transition-metal catalyst (palladium) makes the dynamic kinetic resolution of racemic phenylethylamine possible, conversion to the enantiomerically pure N-acylated form being 75–77% (ee = 99%).

Bibliographic Details
Main Authors: Manfred T. Reetz, Klaus Schimossek
Format: Article in Journal/Newspaper
Language:German
English
French
Published: Swiss Chemical Society 1996
Subjects:
Chemistry
QD1-999
Antarc*
Antarctica
Online Access:https://doaj.org/article/50b446c41b3843bdb1468f15fc579c54
id ftdoajarticles:oai:doaj.org/article:50b446c41b3843bdb1468f15fc579c54
record_format openpolar
spelling ftdoajarticles:oai:doaj.org/article:50b446c41b3843bdb1468f15fc579c54 2023-05-15T13:46:33+02:00 Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst Manfred T. Reetz Klaus Schimossek 1996-12-01T00:00:00Z https://doaj.org/article/50b446c41b3843bdb1468f15fc579c54 DE EN FR ger eng fre Swiss Chemical Society https://www.chimia.ch/chimia/article/view/2765 https://doaj.org/toc/0009-4293 https://doaj.org/toc/2673-2424 0009-4293 2673-2424 https://doaj.org/article/50b446c41b3843bdb1468f15fc579c54 CHIMIA, Vol 50, Iss 12 (1996) Chemistry QD1-999 article 1996 ftdoajarticles 2022-12-31T13:47:42Z The simultaneous use of a biocatalyst (lipase Candida antarctica) and a transition-metal catalyst (palladium) makes the dynamic kinetic resolution of racemic phenylethylamine possible, conversion to the enantiomerically pure N-acylated form being 75–77% (ee = 99%). Article in Journal/Newspaper Antarc* Antarctica Directory of Open Access Journals: DOAJ Articles
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language German
English
French
topic Chemistry
QD1-999
spellingShingle Chemistry
QD1-999
Manfred T. Reetz
Klaus Schimossek
Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
topic_facet Chemistry
QD1-999
description The simultaneous use of a biocatalyst (lipase Candida antarctica) and a transition-metal catalyst (palladium) makes the dynamic kinetic resolution of racemic phenylethylamine possible, conversion to the enantiomerically pure N-acylated form being 75–77% (ee = 99%).
format Article in Journal/Newspaper
author Manfred T. Reetz
Klaus Schimossek
author_facet Manfred T. Reetz
Klaus Schimossek
author_sort Manfred T. Reetz
title Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
title_short Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
title_full Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
title_fullStr Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
title_full_unstemmed Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
title_sort lipase-catalyzed dynamic kinetic resolution of chiral amines: use of palladium as the racemization catalyst
publisher Swiss Chemical Society
publishDate 1996
url https://doaj.org/article/50b446c41b3843bdb1468f15fc579c54
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_source CHIMIA, Vol 50, Iss 12 (1996)
op_relation https://www.chimia.ch/chimia/article/view/2765
https://doaj.org/toc/0009-4293
https://doaj.org/toc/2673-2424
0009-4293
2673-2424
https://doaj.org/article/50b446c41b3843bdb1468f15fc579c54
_version_ 1766244085770747904

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