INTRODUCTION: Some viruses of the Herpesviridae family are frequently the etiologic agents of oral lesions associated with HIV. The aim of this study was to identify the presence of herpes simplex virus types 1 and 2 (HSV-1, HSV-2), Varicella Zoster virus (VZV), Epstein-Barr virus (EBV), human cytom...
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ftdoajarticles:oai:doaj.org/article:50b149dcc57144268f44be80aa1ecab6 2023-05-15T15:10:41+02:00 Raquel dos Santos Pinheiro Dennis de Carvalho Ferreira Flávia Nóbrega Norma Suely de Oliveira Santos Ivete Pomarico Ribeiro de Souza Gloria Fernanda Barbosa de Araujo Castro 2013-01-01T00:00:00Z https://doaj.org/article/50b149dcc57144268f44be80aa1ecab6 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100015 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/50b149dcc57144268f44be80aa1ecab6 Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 1, Pp 15-19 (2013) Herpesvirus Polymerase chain reaction Human immunodeficiency virus Arctic medicine. Tropical medicine RC955-962 article 2013 ftdoajarticles 2022-12-30T21:50:08Z INTRODUCTION: Some viruses of the Herpesviridae family are frequently the etiologic agents of oral lesions associated with HIV. The aim of this study was to identify the presence of herpes simplex virus types 1 and 2 (HSV-1, HSV-2), Varicella Zoster virus (VZV), Epstein-Barr virus (EBV), human cytomegalovirus (HCMV), human herpesvirus type 6, type 7 and type 8 (HHV-6, HHV-7 and HHV-8) in the oral cavity of HIV-infected children/adolescents and verify the association between viral subtypes and clinical factors. METHODS: The cells of oral mucosa were collected from 50 HIV infected children/adolescents, 3-13 years old (mean age 8.66). The majority (66%) of selected were girls, and they were all outpatients at the pediatric AIDS clinic of a public hospital in Rio de Janeiro. Nested-PCR was used to identify the viral types. RESULTS: Absence of immunosuppression was observed in 66% of the children. Highly active antiretroviral therapy (HAART) was used by 72.1% of selected and moderate viral load was observed in 56% of the children/adolescents. Viral types were found in 86% of the children and the subtypes were: HSV-1 (4%), HSV-2 (2%), VZV (4%), EBV (0%), HCMV (24%), HHV6 (18%), HHV-7 (68%), HHV8 (0%). CONCLUSIONS: The use of HAART has helped to reduce oral lesions, especially with herpes virus infections. The health professionals who work with these patients should be aware of such lesions because of their predictive value and the herpes virus can be found circulating in the oral cavity without causing lesions. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Herpesvirus Polymerase chain reaction Human immunodeficiency virus Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Herpesvirus Polymerase chain reaction Human immunodeficiency virus Arctic medicine. Tropical medicine RC955-962 Raquel dos Santos Pinheiro Dennis de Carvalho Ferreira Flávia Nóbrega Norma Suely de Oliveira Santos Ivete Pomarico Ribeiro de Souza Gloria Fernanda Barbosa de Araujo Castro |
topic_facet |
Herpesvirus Polymerase chain reaction Human immunodeficiency virus Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Some viruses of the Herpesviridae family are frequently the etiologic agents of oral lesions associated with HIV. The aim of this study was to identify the presence of herpes simplex virus types 1 and 2 (HSV-1, HSV-2), Varicella Zoster virus (VZV), Epstein-Barr virus (EBV), human cytomegalovirus (HCMV), human herpesvirus type 6, type 7 and type 8 (HHV-6, HHV-7 and HHV-8) in the oral cavity of HIV-infected children/adolescents and verify the association between viral subtypes and clinical factors. METHODS: The cells of oral mucosa were collected from 50 HIV infected children/adolescents, 3-13 years old (mean age 8.66). The majority (66%) of selected were girls, and they were all outpatients at the pediatric AIDS clinic of a public hospital in Rio de Janeiro. Nested-PCR was used to identify the viral types. RESULTS: Absence of immunosuppression was observed in 66% of the children. Highly active antiretroviral therapy (HAART) was used by 72.1% of selected and moderate viral load was observed in 56% of the children/adolescents. Viral types were found in 86% of the children and the subtypes were: HSV-1 (4%), HSV-2 (2%), VZV (4%), EBV (0%), HCMV (24%), HHV6 (18%), HHV-7 (68%), HHV8 (0%). CONCLUSIONS: The use of HAART has helped to reduce oral lesions, especially with herpes virus infections. The health professionals who work with these patients should be aware of such lesions because of their predictive value and the herpes virus can be found circulating in the oral cavity without causing lesions. |
format |
Article in Journal/Newspaper |
author |
Raquel dos Santos Pinheiro Dennis de Carvalho Ferreira Flávia Nóbrega Norma Suely de Oliveira Santos Ivete Pomarico Ribeiro de Souza Gloria Fernanda Barbosa de Araujo Castro |
author_facet |
Raquel dos Santos Pinheiro Dennis de Carvalho Ferreira Flávia Nóbrega Norma Suely de Oliveira Santos Ivete Pomarico Ribeiro de Souza Gloria Fernanda Barbosa de Araujo Castro |
author_sort |
Raquel dos Santos Pinheiro |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2013 |
url |
https://doaj.org/article/50b149dcc57144268f44be80aa1ecab6 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 1, Pp 15-19 (2013) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100015 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/50b149dcc57144268f44be80aa1ecab6 |
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1766341662252990464 |