Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar
Abstract Background To understand the Plasmodium vivax malaria transmission intensity and to assess the effectiveness of prevention and control measures taken along the China–Myanmar border, a catalytic model was used to calculate the seroconversion rate, an important indicator of malaria transmissi...
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ftdoajarticles:oai:doaj.org/article:4efe9921d0ca4ff783b1013b5cf56bb0 2023-05-15T15:09:21+02:00 Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar Meixue Yao Lishun Xiao Xiaodong Sun Zurui Lin Xiao Hao Qiong-qiong Bai De-Hui Yin 2022-03-01T00:00:00Z https://doi.org/10.1186/s12936-022-04096-8 https://doaj.org/article/4efe9921d0ca4ff783b1013b5cf56bb0 EN eng BMC https://doi.org/10.1186/s12936-022-04096-8 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04096-8 1475-2875 https://doaj.org/article/4efe9921d0ca4ff783b1013b5cf56bb0 Malaria Journal, Vol 21, Iss 1, Pp 1-9 (2022) Plasmodium vivax Surveillance Serology Seroconversion Rate Transmission intensity Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2022 ftdoajarticles https://doi.org/10.1186/s12936-022-04096-8 2022-12-31T10:23:26Z Abstract Background To understand the Plasmodium vivax malaria transmission intensity and to assess the effectiveness of prevention and control measures taken along the China–Myanmar border, a catalytic model was used to calculate the seroconversion rate, an important indicator of malaria transmission intensity with high sensitivity, which is particularly useful in areas of low transmission. Methods Five counties in Yunnan Province bordering Myanmar were selected as survey sites, and subjects were obtained in each county by stratified random sampling in 2013–2014. Fingerstick blood was collected from each subject and tested for antibodies to P. vivax Merozoite Surface Protein 1-19 (PvMSP1-19) using indirect ELISA. A catalytic conversion model was used to assess the transmission intensity of P. vivax malaria based on the maximum likelihood of generating a community seroconversion rate. Results A total of 3064 valid blood samples were collected. Antibody levels were positively correlated with age. The seroconversion rate (SCR) values for each village were Luoping (0.0054), Jingqiao (0.0061), Longpen (0.0087), Eluo (0.0079), Banwang (0.0042) and Banbie (0.0046), respectively. Conclusion Overall, the intensity of P. vivax malaria transmission in the border areas of Yunnan Province is low and not entirely consistent across counties. Consecutive serological surveys are needed to provide a sensitive evaluation of transmission dynamics and can help to confirm areas where infection is no longer present. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 21 1 |
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Directory of Open Access Journals: DOAJ Articles |
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Plasmodium vivax Surveillance Serology Seroconversion Rate Transmission intensity Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Plasmodium vivax Surveillance Serology Seroconversion Rate Transmission intensity Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Meixue Yao Lishun Xiao Xiaodong Sun Zurui Lin Xiao Hao Qiong-qiong Bai De-Hui Yin Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar |
topic_facet |
Plasmodium vivax Surveillance Serology Seroconversion Rate Transmission intensity Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background To understand the Plasmodium vivax malaria transmission intensity and to assess the effectiveness of prevention and control measures taken along the China–Myanmar border, a catalytic model was used to calculate the seroconversion rate, an important indicator of malaria transmission intensity with high sensitivity, which is particularly useful in areas of low transmission. Methods Five counties in Yunnan Province bordering Myanmar were selected as survey sites, and subjects were obtained in each county by stratified random sampling in 2013–2014. Fingerstick blood was collected from each subject and tested for antibodies to P. vivax Merozoite Surface Protein 1-19 (PvMSP1-19) using indirect ELISA. A catalytic conversion model was used to assess the transmission intensity of P. vivax malaria based on the maximum likelihood of generating a community seroconversion rate. Results A total of 3064 valid blood samples were collected. Antibody levels were positively correlated with age. The seroconversion rate (SCR) values for each village were Luoping (0.0054), Jingqiao (0.0061), Longpen (0.0087), Eluo (0.0079), Banwang (0.0042) and Banbie (0.0046), respectively. Conclusion Overall, the intensity of P. vivax malaria transmission in the border areas of Yunnan Province is low and not entirely consistent across counties. Consecutive serological surveys are needed to provide a sensitive evaluation of transmission dynamics and can help to confirm areas where infection is no longer present. |
format |
Article in Journal/Newspaper |
author |
Meixue Yao Lishun Xiao Xiaodong Sun Zurui Lin Xiao Hao Qiong-qiong Bai De-Hui Yin |
author_facet |
Meixue Yao Lishun Xiao Xiaodong Sun Zurui Lin Xiao Hao Qiong-qiong Bai De-Hui Yin |
author_sort |
Meixue Yao |
title |
Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar |
title_short |
Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar |
title_full |
Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar |
title_fullStr |
Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar |
title_full_unstemmed |
Surveillance of Plasmodium vivax transmission using serological models in the border areas of China–Myanmar |
title_sort |
surveillance of plasmodium vivax transmission using serological models in the border areas of china–myanmar |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s12936-022-04096-8 https://doaj.org/article/4efe9921d0ca4ff783b1013b5cf56bb0 |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 21, Iss 1, Pp 1-9 (2022) |
op_relation |
https://doi.org/10.1186/s12936-022-04096-8 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04096-8 1475-2875 https://doaj.org/article/4efe9921d0ca4ff783b1013b5cf56bb0 |
op_doi |
https://doi.org/10.1186/s12936-022-04096-8 |
container_title |
Malaria Journal |
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21 |
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1 |
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1766340562971000832 |