Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus
Bone mineral density (BMD) and fracture risk are elevated in adults with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2D). This study aimed to compare bone health among Inuit women with IFG, T2D and normoglycemia. The study included Inuit women (≥40 y) with IFG (n = 57), T2D (n = 72)...
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ftdoajarticles:oai:doaj.org/article:4e2123f893f44f62bbb3cf18bc92ab76 2023-05-15T15:09:43+02:00 Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus Nihal A. Natour Suzanne N. Morin Grace M. Egeland Hope A. Weiler 2019-01-01T00:00:00Z https://doi.org/10.1080/22423982.2019.1601056 https://doaj.org/article/4e2123f893f44f62bbb3cf18bc92ab76 EN eng Taylor & Francis Group http://dx.doi.org/10.1080/22423982.2019.1601056 https://doaj.org/toc/2242-3982 2242-3982 doi:10.1080/22423982.2019.1601056 https://doaj.org/article/4e2123f893f44f62bbb3cf18bc92ab76 International Journal of Circumpolar Health, Vol 78, Iss 1 (2019) type 2 diabetes mellitus impaired fasting glucose bone mineral density traditional food inuit women Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1080/22423982.2019.1601056 2022-12-31T06:13:48Z Bone mineral density (BMD) and fracture risk are elevated in adults with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2D). This study aimed to compare bone health among Inuit women with IFG, T2D and normoglycemia. The study included Inuit women (≥40 y) with IFG (n = 57), T2D (n = 72) or normoglycemia (n = 340) from the International Polar Year Inuit Health Survey 2007–2008 in Canada. Distal one-third forearm BMD (FaBMD) was measured using a peripheral instantaneous x-ray imager. Anthropometry, fasting plasma glucose (FPG), serum adiponectin, leptin and 25-hydroxyvitamin D (25(OH)D) were measured. Traditional food intakes were surveyed. Data were analysed using mixed model ANOVA and regression models. The median age was 53 (IFG: IQR 48, 67) y and 56 (T2D: IQR 49, 63) y. Compared to normoglycemic women, FaBMD and T-scores were significantly lower in women with T2D, but not with IFG. Frequency of marine mammal intakes (ß = 0.145; 95%CI: 0.018, 0.053, p = 0.0001) positively related to FaBMD. The odds ratio of having a T-score consistent with osteoporosis was lower among women with T2D and higher BMI, while aging increased the risk. Although T2D associates with lower BMD among Inuit women, risk of osteoporosis is tempered, possibly by maintenance of a traditional lifestyle. Article in Journal/Newspaper Arctic Circumpolar Health International Journal of Circumpolar Health International Polar Year inuit Directory of Open Access Journals: DOAJ Articles Arctic Canada International Journal of Circumpolar Health 78 1 1601056 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
type 2 diabetes mellitus impaired fasting glucose bone mineral density traditional food inuit women Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
type 2 diabetes mellitus impaired fasting glucose bone mineral density traditional food inuit women Arctic medicine. Tropical medicine RC955-962 Nihal A. Natour Suzanne N. Morin Grace M. Egeland Hope A. Weiler Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus |
topic_facet |
type 2 diabetes mellitus impaired fasting glucose bone mineral density traditional food inuit women Arctic medicine. Tropical medicine RC955-962 |
description |
Bone mineral density (BMD) and fracture risk are elevated in adults with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2D). This study aimed to compare bone health among Inuit women with IFG, T2D and normoglycemia. The study included Inuit women (≥40 y) with IFG (n = 57), T2D (n = 72) or normoglycemia (n = 340) from the International Polar Year Inuit Health Survey 2007–2008 in Canada. Distal one-third forearm BMD (FaBMD) was measured using a peripheral instantaneous x-ray imager. Anthropometry, fasting plasma glucose (FPG), serum adiponectin, leptin and 25-hydroxyvitamin D (25(OH)D) were measured. Traditional food intakes were surveyed. Data were analysed using mixed model ANOVA and regression models. The median age was 53 (IFG: IQR 48, 67) y and 56 (T2D: IQR 49, 63) y. Compared to normoglycemic women, FaBMD and T-scores were significantly lower in women with T2D, but not with IFG. Frequency of marine mammal intakes (ß = 0.145; 95%CI: 0.018, 0.053, p = 0.0001) positively related to FaBMD. The odds ratio of having a T-score consistent with osteoporosis was lower among women with T2D and higher BMI, while aging increased the risk. Although T2D associates with lower BMD among Inuit women, risk of osteoporosis is tempered, possibly by maintenance of a traditional lifestyle. |
format |
Article in Journal/Newspaper |
author |
Nihal A. Natour Suzanne N. Morin Grace M. Egeland Hope A. Weiler |
author_facet |
Nihal A. Natour Suzanne N. Morin Grace M. Egeland Hope A. Weiler |
author_sort |
Nihal A. Natour |
title |
Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus |
title_short |
Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus |
title_full |
Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus |
title_fullStr |
Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus |
title_full_unstemmed |
Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus |
title_sort |
forearm bone density is not elevated in inuit women with impaired fasting glucose or type 2 diabetes mellitus |
publisher |
Taylor & Francis Group |
publishDate |
2019 |
url |
https://doi.org/10.1080/22423982.2019.1601056 https://doaj.org/article/4e2123f893f44f62bbb3cf18bc92ab76 |
geographic |
Arctic Canada |
geographic_facet |
Arctic Canada |
genre |
Arctic Circumpolar Health International Journal of Circumpolar Health International Polar Year inuit |
genre_facet |
Arctic Circumpolar Health International Journal of Circumpolar Health International Polar Year inuit |
op_source |
International Journal of Circumpolar Health, Vol 78, Iss 1 (2019) |
op_relation |
http://dx.doi.org/10.1080/22423982.2019.1601056 https://doaj.org/toc/2242-3982 2242-3982 doi:10.1080/22423982.2019.1601056 https://doaj.org/article/4e2123f893f44f62bbb3cf18bc92ab76 |
op_doi |
https://doi.org/10.1080/22423982.2019.1601056 |
container_title |
International Journal of Circumpolar Health |
container_volume |
78 |
container_issue |
1 |
container_start_page |
1601056 |
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1766340847184379904 |